GEISHA - A Chicken Embryo Gene Expression Database
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CHRNA7
cholinergic receptor nicotinic alpha 7 subunit

The human orthologue of this gene is associated
with the following human disease:
Gene
Official SymbolCHRNA7
Official Full Namecholinergic receptor nicotinic alpha 7 subunit
CGNC ID48996
also known asneuronal acetylcholine receptor subunit alpha-7|cholinergic receptor, nicotinic, alpha 7 (neuronal)|cholinergic receptor, nicotinic, alpha polypeptide 7
gene typeprotein-coding
Genomic Map
 Ensembl ID not known
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
RNANM_204181
PolypeptideNP_989512
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST ProfileGga.4000
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly34826FBgn0028875
Human1139ENSG00000175344MIM:118511MIM:118511
Mouse11441ENSMUSG00000030525All phenotypic alleles (3):Targeted, knock-out(1) Targeted, other(2) MGI:99779
Xenopus100493611990455
Zebrafish394199ENSDARG00000035785ZDB-GENE-040108-3ZFIN:ZDB-GENE-040108-3
Gene Ontology
Molecular Functionacetylcholine-activated cation-selective channel activity, acetylcholine binding, more...acetylcholine receptor activity, beta-amyloid binding, chloride channel regulator activity, protein homodimerization activity, toxic substance binding
Biological Processactivation of MAPK activity, calcium ion transport, cellular calcium ion homeostasis, cognition, more...negative regulation of tumor necrosis factor production, positive regulation of angiogenesis, positive regulation of cell proliferation, response to hypoxia, response to nicotine, signal transduction, synaptic transmission
Cellular Componentacetylcholine-gated channel complex, cell junction, plasma membrane, postsynaptic membrane
Links to other databases
Entrez Gene374001
Ensembl Gene
KEGGgga:374001
GEISHA IdCHRNA7.Ikonomov.1998Data SourcePublication
Complete cDNA Template Probeshow
GAGCCGACATCGCAGGGAGAGCCCCGCGCGGGCGCAGGAGGGGGCCGGGCGGCGAGAGGTCCGCGGCGGCGACGGAGGC
TCCCGGCTCCGGCTGTTGCCGGGCTCCCGGAATGGGCCTCCAGGCGCTGATGCTGTGGCTGCTGGCGGCGGCGGGGCTC
GTGCGCGAGTCCCTGCAAGGAGAGTTCCAAAGGAAGCTGTACAAGGAGCTGCTGAAGAACTACAACCCTCTGGAACGAC
CAGTTGCAAATGACTCCCAGCCGCTCACTGTCTATTTCACTCTCAGCCTCATGCAGATCATGGATGTGGATGAAAAGAA
TCAAGTATTAACAACAAACATCTGGCTACAAATGTACTGGACAGATCATTACTTACAGTGGAATGTGTCTGAATACCCT
GGAGTGAAGAACGTCCGTTTTCCTGATGGACTGATTTGGAAGCCAGATATTCTTCTCTATAACAGTGCTGATGAAAGAT
TTGATGCTACATTTCACACTAATGTTTTAGTCAATTCTTCGGGACACTGCCAATATCTGCCACCAGGCATATTTAAAAG
CTCATGCTACATAGACGTGCGTTGGTTTCCATTTGATGTTCAGAAGTGCAATCTGAAGTTTGGATCTTGGACATATGGA
GGCTGGTCCTTAGACTTACAAATGCAAGAAGCAGATATATCCGGCTATATTTCAAATGGAGAGTGGGATTTAGTAGGAA
TTCCTGGGAAGAGAACTGAGAGCTTTTATGAGTGCTGTAAAGAACCATACCCAGATATCACATTCACAGTAACCATGAG
ACGCAGAACTCTCTACTACGGGCTCAACCTTCTTATTCCCTGTGTACTGATATCAGCACTTGCCTTATTAGTCTTTCTG
CTTCCAGCAGACTCAGGAGAAAAGATCTCACTAGGTATAACAGTTTTATTGTCTCTCACCGTCTTCATGTTACTCGTGG
CTGAAATTATGCCAGCAACATCTGATTCTGTGCCCTTAATTGCTCAGTATTTTGCCAGCACCATGATTATTGTTGGCCT
CTCTGTTGTTGTCACTGTTATCGTTCTACAATACCATCATCACGATCCAGATGGGGGAAAAATGCCTAAATGGACAAGA
GTCATCCTTCTGAATTGGTGTGCTTGGTTTCTGAGGATGAAGAGACCAGGGGAAGATAAAGTGCGTCCCGCCTGTCAAC
ATAAACAGCGTCGATGCAGCCTGTCAAGCATGGAGATGAACACTGTGAGTGGTCAGCAATGCAGTAATGGGAACATGCT
GTATATTGGGTTTCGAGGGCTGGATGGGGTTCACTGCACACCCACCACTGATTCAGGGGTGATCTGTGGGAGGATGACC
TGTTCACCAACAGAGGAAGAAAATCTTCTGCACAGTGGCCACCCCTCTGAAGGCGACCCAGATTTGGCTAAGATCCTGG
AAGAGGTCAGATACATTGCAAACAGGTTCAGAGACCAGGATGAAGAAGAAGCCATTTGCAACGAATGGAAGTTTGCAGC
CTCTGTAGTAGATCGGCTCTGCTTGATGGCATTTTCGGTCTTCACCATCATTTGTACAATTGGCATCTTAATGTCAGCA
CCAAACTTTGTAGAGGCTGTCTCTAAAGATTTTGCTTAACTCCTAACTATGATTTGATTCTCTGAAGTATCATATGTAG
CAAATAAGAGTGTATTTTTTTTTGTTTGTTTGCTTGTTTTTAATGAGTACACTGTATCTCATCGTCCTCTGTCTTTTGC
CCTCCCCCCTATTCCCCCAGCATTCCTCTGACCCTGGGCTCCTTTCTGAACAGGAGCACCCTTTCAGAAGGGGAGCCAG
GGATCCCTCCCTGGGCTGTATGCCCAGCTCCTCTAAGCACTTTGCTTTGGGAGATGCAAAGTGAGTGCAAGACCCTTCA
GAATGAAAGGATACTGCTCCAGCATCTTTTATGCATTTCAAACTGGCTAGTACATAAATTAATAGGTAGGTAATGCCAG
AAATGTCATTTCTTCCAGAATTTACTTTAAAAGATAGAAGTTAGCCCTATGTTTTGGAGAGGATTAAATCTGAATGAAA
GGAAACTCAAACAGAAGAGGGAAAAAAAGGGTAACAAGACCTTGCTTTTCAGTCTCTGGATGTTAGCGAGTACTGAGCT
CACAGCTCACTCACAACCAGTCACATTTTAAATCCCTCAACGCATTTTACAGAGAGCTTATGTGAGTATACAGGATTCT
GATTTTGCCTGAGACTCCAGAAAGATGAAAGTCAAGATGAAACAGCACATATCTTGTCCTTCTGTCACTTCCTGGACCT
GACCTAGAAGTATGGCCTGGATTCTTAAAAAGGCATCACAGTAATTGTGTTTATTACAACTCCCTTCTCTCCAGAACAA
CATTCTTTCAACTAATGACTTCTGTCGGTTTTTACCCTTTGCTGTGACATTAAAAAAGTATTTACGATGGCTTTACCCT
CATTTGTTAAAAAAAATAATAATAAATTACATACAGTTGTCTCTTTACTTTTCTACATTGAAATCCAGTTAACAGTAAC
TGTCTTGTACAGGCTCAAACACAATGACAGATCTAAAGCAAAAAAAAAAAAAACATTAAATCATCAGATCCAGCTTTTC
ATTTCAATGTGAAATGTCTGATCTACTGTTTGCTTAGCCTTTTATAGACTTCTTTTCATTGAGTCATCGTAACATATCC
TAACAAGAAAACTGCATCCTTTCTGCTCAGTTTATCGTACAAAAAACACTAATGAATTATAAATACTATATATAAACTA
TACATACATCCCAGGAAAGATTAAATCTTAAATA
CitationIkonomov OC, Kulesa MC, Shisheva AC, Jacob MH. Innervation and target tissue interactions induce Rab-GDP dissociation inhibitor (GDI) expression during peripheral synapse formation in developing chick ciliary ganglion neurons in situ. J Neurosci. 1998 Aug 15;18(16):6331-9.
CopyrightCopyright © 1998 Society for Neuroscience
CommentsInsufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_204181.2).
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
31-44
stage 42
stage 44
Central Nervous System
Eye
Sensory Organs
E14-E19, ciliary ganglion neurons
 Data from NCBI Unigene EST Profile
Unigene ID: Gga.4000

Mouse

EmageMGI:99779
EurexpressMGI:99779
MGI GXDMGI:99779

Frog

Xenbase990455

Fruit Fly

BDGPFBgn0028875

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-040108-3
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