GEISHA - A Chicken Embryo Gene Expression Database
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PDGFA
platelet derived growth factor subunit A

Gene
Official SymbolPDGFA
Official Full Nameplatelet derived growth factor subunit A
CGNC ID49079
also known asPDGF-A, platelet-derived growth factor subunit A|PDGF-A (S1)|platelet-derived growth factor A chain long form|platelet-derived growth factor A chain short form type 1|platelet-derived growth factor A chain short form type 2|platelet-derived growth factor A-chain|platelet-derived growth factor alpha polypeptide, platelet-derived growth factor alpha polypeptide, PDGF-alpha
gene typeprotein-coding
Genomic Map
 Ensembl ID not known
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
RNANM_204306
PolypeptideNP_989637
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST ProfileGga.3899
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly
Human5154ENSG00000197461MIM:173430
Mouse18590ENSMUSG00000025856All phenotypic alleles (2):Targeted, knock-out(1) Targeted, other(1) MGI:97527
Xenopus100038202, 397765484494
Zebrafish378480, 767790ENSDARG00000055505, ENSDARG00000058424ZDB-GENE-030918-2, ZDB-GENE-060929-124ZFIN:ZDB-GENE-030918-2, ZFIN:ZDB-GENE-060929-124
Gene Ontology
Molecular Function
Biological Process
Cellular Component
Links to other databases
Entrez Gene374196
Ensembl Gene
KEGGgga:374196

Entry 1

GEISHA IdChEST1037j8Data SourceGEISHA ISH Analysis
Forward cDNA Template Probeshow
GCTCGAGCTAAAGTGCACTAGACCGCGATGAGGACCTGGGCTTGCGTTTTGCTGATAGGTTTTGGCTACCTGTCCTTTA
CCTCCTGCGAGGAGGCCGAGATCCCGCAGGAGCTGATCGAGCGGCTGGCGCACAGCGAGATCCACAGCATCCGCGACTT
GCAGCGCCTCCTGGAGATTGACTCCGTAGGATACGATGATGTTTCAGAGACAAACTTGAGGTCTTATAGTGTTCATTCT
GCTAAACATGTGCAAGAGAACCGTCCTGTGCCCATTCGCAGAAAAAGAAGCATTGAGGAGGCCATCCCGGCTGTCTGCA
AAACACGGACGGTGATATATGAGATACCTCGGAGTCAGATTGATCCCACCTCGGCCAACTTCCTGATATGGCCGCCGTG
CGTGGAGGTGAAGCGCTGCACTGGCTGCTGCAACACCAGCAGTGTGAAATGCCAGCCCTCCCGGATACATCACAGAAGT
GTCAAGCTGCATTTTTGAGGAGGGAGAGCGAGATGGCTAGGCTTGCAGTAACACGTTGTGTCGTCATAAATGCTACAGC
CACCATCTGTTTCCAGCCCACGACTTGAAAGAAAACTGAGCAGTAATCTCGTAATTCACATGAGCATTTTACACTTGTG
AACCCTTCCCAACCTTTGTCTCATAACGAGGGGAGTGCATGGTGCTAAGGTTTGTATTTTTCCTGCGCGTATCAGTGTT
TATTTGTATGTCTCTTTCTGTATACTTTATTTTATTTTGTTCCATGGTCCCCTT
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
4-6
stage 4
stage 4
stage 6
stage 6
Area Opaca
Epiblast
Extraembryonic
Neural Plate/Tube
Surface Ectoderm
 
7-12
stage 8
stage 8
stage 11
stage 11
Anterior Intestinal Portal
Epiblast
Extraembryonic
Head Mesenchyme
Lateral Plate Mesoderm
Paraxial Mesoderm
asymmetrical
13-18
stage 16
stage 17
Face Mesenchyme
Lateral Plate Mesoderm
Leg Mesenchyme
Nasal Placcode/Nerve
Paraxial Mesoderm
Pharyngeal Arches and Clefts
Somatopleure
 
19-20
stage 20
Allantois
Dermomyotome
Ectoderm
Face Mesenchyme
Lateral Plate Mesoderm
Leg
Pharyngeal Arches and Clefts
Wing
 

Entry 2

GEISHA IdPDGFA.Chapman.2006Data SourcePublication
Complete cDNA Template Probeshow
CCACCCTGAATGCGGAGGACCCCCGAAGCCACCCCGCTGCCTTTCCCCTGAGGGATGGTACTGAATTTCTGCGCGGCAG
GAGCCGGCCTGCAGCTCCTCTCCATCAGCGTTGCCTTCCCTCCGTATCTAAAGTGCACTAGACCGCGATGAGGACCTGG
GCTTGCGTTTTGCTGATAGGTTTTGGCTACCTGTCCTTTACCTCCTGCGAGGAGGCCGAGATCCCGCAGGAGCTGATCG
AGCGGCTGGCGCACAGCGAGATCCACAGCATCCGCGACTTGCAGCGCCTCCTGGAGATTGACTCCGTAGGATACGATGA
TGTTTCAGAGACAAACTTGAGGTCTTATAGTGTTCATTCTGCTAAACATGTGCAAGAGAACCGTCCTGTGCCCATTCGC
AGAAAAAGAAGCATTGAGGAGGCCATCCCGGCTGTCTGCAAAACACGGACGGTGATATATGAGATACCTCGGAGTCAGA
TTGATCCCACCTCGGCCAACTTCCTGATATGGCCGCCGTGCGTGGAGGTGAAGCGCTGCACTGGCTGCTGCAACACCAG
CAGTGTGAAATGCCAGCCCTCCCGGATACATCACAGAAGTGTCAAGGTGGCAAAAGTGGAATATGTTAGAAAAAAGCCA
AAATTAAAAGAAGTTCTGGTGAGATTAGAAGAGCATATGGAATGCACCTGTACATCAACAAATACTAATTCAGATTATA
GAGAAGAAGAAACTGATTAACAGGTATTTATTGGGAGTAGTATGATAGAAGCAAAGATTTTC
CitationChapman SC, Cai Q, Bleyl SB, Schoenwolf GC. Restricted expression of Fgf16 within the developing chick inner ear. Dev Dyn. 2006 Aug;235(8):2276-81. PMID: 16786592 [PubMed - indexed for MEDLINE]
CopyrightCopyright © 2006 Wiley-Liss, Inc.
CommentsInsufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_204306).
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
19
stage 19
Ear/Otic Placcode
Otocyst

Entry 3

GEISHA IdPDGFA.Smith.2005Data SourcePublication
Complete cDNA Template Probeshow
GCTTGCGTTTTGCTGATAGGTTTTGGCTACCTGTCCTTTACCTCCTGCGAGGAGGCCGAGATCCCGCAGGAGCTGATCG
AGCGGCTGGCGCACAGCGAGATCCACAGCATCCGCGACTTGCAGCGCCTCCTGGAGATTGACTCCGTAGGATACGATGA
TGTTTCAGAGACAAACTTGAGGTCTTATAGTGTTCATTCTGCTAAACATGTGCAAGAGAACCGTCCTGTGCCCATTCGC
AGAAAAAGAAGCATTGAGGAGGCCATCCCGGCTGTCTGCAAAACACGGACGGTGATATATGAGATACCTCGGAGTCAGA
TTGATCCCACCTCGGCCAACTTCCTGATATGGCCGCCGTGCGTGGAGGTGAAGCGCTGCACTGGCTGCTGCAACACCAG
CAGTGTGAA
CitationSmith CA, McClive PJ, Hudson Q, Sinclair AH. (2005) Male-specific cell migration into the developing gonad is a conserved process involving PDGF signalling. Dev Biol. 2005 Aug 15;284(2):337-50.
CopyrightCopyright © 2005 Elsevier Inc. All rights reserved.
CommentsAccording to the authors, the cDNA template used for G. gallus platelet-derived growth factor alpha (PDGF-A) was obtained from the NCBI accession NM_204306, bases 159–562. Sequence below was obtained from NCBI using the information provided.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
25-30
stage 30
Gonad
Testis
 
31-35
stage 33
stage 35
Gonad
Ovary
Testis
 

Entry 4

GEISHA IdPDGFA.McCabe.2008Data SourcePublication
Complete cDNA Template Probeshow
CCACCCTGAATGCGGAGGACCCCCGAAGCCACCCCGCTGCCTTTCCCCTGAGGGATGGTACTGAATTTCTGCGCGGCAG
GAGCCGGCCTGCAGCTCCTCTCCATCAGCGTTGCCTTCCCTCCGTATCTAAAGTGCACTAGACCGCGATGAGGACCTGG
GCTTGCGTTTTGCTGATAGGTTTTGGCTACCTGTCCTTTACCTCCTGCGAGGAGGCCGAGATCCCGCAGGAGCTGATCG
AGCGGCTGGCGCACAGCGAGATCCACAGCATCCGCGACTTGCAGCGCCTCCTGGAGATTGACTCCGTAGGATACGATGA
TGTTTCAGAGACAAACTTGAGGTCTTATAGTGTTCATTCTGCTAAACATGTGCAAGAGAACCGTCCTGTGCCCATTCGC
AGAAAAAGAAGCATTGAGGAGGCCATCCCGGCTGTCTGCAAAACACGGACGGTGATATATGAGATACCTCGGAGTCAGA
TTGATCCCACCTCGGCCAACTTCCTGATATGGCCGCCGTGCGTGGAGGTGAAGCGCTGCACTGGCTGCTGCAACACCAG
CAGTGTGAAATGCCAGCCCTCCCGGATACATCACAGAAGTGTCAAGGTGGCAAAAGTGGAATATGTTAGAAAAAAGCCA
AAATTAAAAGAAGTTCTGGTGAGATTAGAAGAGCATATGGAATGCACCTGTACATCAACAAATACTAATTCAGATTATA
GAGAAGAAGAAACTGATTAACAGGTATTTATTGGGAGTAGTATGATAGAAGCAAAGATTTTC
CitationMcCabe KL, Bronner-Fraser M. Essential role for PDGF signaling in ophthalmic trigeminal placode induction. Development. 2008 May;135(10):1863-74. Epub 2008 Apr 16.
CopyrightPublished by The Company of Biologists 2007. This material is protected by a copyright retained by the authors. Permission granted by Dr. Bronner-Fraser.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
7-10
stage 8
stage 8
stage 10
Early Endoderm
Ectoderm
Endoderm
Neural Plate/Tube
 

Entry 5

GEISHA IdPDGFA.YANG.2008Data SourcePublication
Complete cDNA Template Probeshow
GCGGCTCGAGCACAGGTGATGGGCGTTTCGGCTGCGCTCCGGATCGACTCCTTGGGTTTCACTTTGGTCTGATCTAAGC
AAATATGCAGAAGTACCGGCTGGTCTAGTCCTAAGAGCCAAGAGGAGCGAGGGAGAGCGGCAGAAAGGAGAGCGGCCGC
GCTCCCGTTGGAGAGGAACGTACAAACAGCGGCAGCGCCGTAATTCCAGCACCGCCGCCCCGAGGCAGCCCCGAGCCAC
CCTGAATGCGGAGGACCCCCGAAGCCACCCCGCTGCCTTTCCCCTGAGGGATGGTACTGAATTTCTGCGCGGCAGGAGC
CGGCCTGCAGCTCCTCTCCATCAGCGTTGCCTTCCCTCCGTATCTAAAGTGCACTAGACCGCGATGAGGACCTGGGCTT
GCGTTTTGCTGATAGGTTTTGGCTACCTGTCCTTTACCTCCTGCGAGGAGGCCGAGATCCCGCAGGAGCTGATCGAGCG
GCTGGCGCACAGCGAGATCCACAGCATCCGCGACTTGCAGCGCCTCCTGGAGATTGACTCCGTAGGATACGATGATGTT
TCAGAGACAAACTTGAGGTCTTATAGTGTTCATTCTGCTAAACATGTGCAAGAGAACCGTCCTGTGCCCATTCGCAGAA
AAAGAAGCATTGACGGAGGCCATCCCGGCTGTCTGCAAAACACGGACGGTGATATATGAGATACCTCGGAGTCAGATTG
ATCCCACCTCGGCCAACTTCCTGGATATGGCCGACGTGCGTGAAGGTGAAG
CitationYang X, Chrisman H, Weijer CJ. PDGF signalling controls the migration of mesoderm cells during chick gastrulation by regulating N-cadherin expression. Development. 2008 Nov;135(21):3521-30. Epub 2008 Oct 2.
Copyright© 2008
CommentsThe cDNA template used to generate the probe was obtained from EST - ChEST460a12 as described.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
1-3
stage 3
stage 3
Epiblast
 
4-6
stage 5
stage 6
Epiblast
 
7-8
stage 7
stage 8
Early Mesoderm
Epiblast
Neural Plate/Tube
 
 Data from NCBI Unigene EST Profile
Unigene ID: Gga.3899

Mouse

EmageMGI:97527
EurexpressMGI:97527
MGI GXDMGI:97527

Frog

Xenbase484494

Fruit Fly

BDGP

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-030918-2, ZDB-GENE-060929-124
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