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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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TBX3
T-box 3

The human orthologue of this gene is associated
with the following human disease:

Ulnar-mammary syndrome

Gene

Official Symbol	TBX3
Official Full Name	T-box 3
CGNC ID	49082
also known as	T-box transcription factor TBX3\|T-Box protein 3, T-box transcription factor TBX3, T-box protein 3, Tbox3
gene type	protein-coding

Genomic Map

	Ensembl ID not known
	NCBI
	UCSC
	Gallus-Browse

Sequence Information

Genomic
RNA	NM_001270878
Polypeptide	NP_001257807
Sequence Clusters/ESTs	Unigene

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.27708

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly
Human	6926	ENSG00000135111	MIM:181450	MIM:601621
Mouse	21386	ENSMUSG00000018604	All phenotypic alleles (4):Targeted, knock-out(3) Targeted, other(1)	MGI:98495
Xenopus	613116, 397816, 373612			1018230
Zebrafish	556870	ENSDARG00000002216	ZDB-GENE-070209-80, ZDB-GENE-060531-144	ZFIN:ZDB-GENE-070209-80, ZFIN:ZDB-GENE-060531-144

Gene Ontology

Molecular Function	sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity
Biological Process	anterior/posterior axis specification, embryo, cell aging, embryonic digit morphogenesis, more...
Cellular Component	nucleus

Links to other databases

Entrez Gene	374202
Ensembl Gene
KEGG	gga:374202

Entry 1

GEISHA Id	pgm2n.pk008.e12	Data Source	GEISHA ISH Analysis
Forward cDNA Template Probe	show CAGAGACTGCTATCCCCTTTTCTTCCCTGGGCCACCAGGCAGCAGCCCATCTGAGGCCTTTAAAAACTCTGGAGCCAGA GGAAGAAGTGGAAGACGACCCGAAAGTGCACCTGGAAGCCAAAGAGCTTTGGGAACAATTCCATAAAAGAGGCACGGAG ATGGTGATCACCAAATCGGGAAGGAGAATGTTTCCTCCGTTTAAAGTGAGATGCACTGGACTGGATAAAAAGGCCAAGT ACATTTTATTGATGGATATTGTGGCGGCTGACGACTGTAGGTACAAATTCCATAATTCCCGGTGGATGGTAGCCGGCAA AGCTGACCCTGAAATGCCAAAGAGAATGTACATCCACCCGGACAGCCCGGCCACCGGAGAACAATGGATGTCCAAAGTC GTCACCTTTCACAAGCTGAAGCTCACTAACAACATCTCCGACAAGCACGGATTTACCATTTTAAACTCCATGCACAAGT ACCAGCCCCGCTTCCACATCGTCCGAGCGAACGATATTCTCAAGCTTCCCTACAGCACGTTCCGGACCTACGTGTTCCC GGAGACTGAATTCATCGCAGTGACCGCATACCAGAATGATAAGATCACTCAATTAAAAATTGACAACAACCCCTTTGCC AAAGGTTTTCGCGACACTGGGAATGGAAGGAGGGAAAAAAGGAAGCAGCTGACCCTGCAGTCCATGCGGGTGTACGACG AGAGGCAGAAGAAAGAAAACCCCACTTCGGACGAATCGTCCAACGAGCAGACAGCCTTCAAGTGCTTCGCGCAGTCCTC CTGCCCCGCCGTGCCCGCCGTCGGCACCTCCAGCCNTCAAGATCTCTGTCCCAGCGA

Stage

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Location (click to highlight)

Comments (click to highlight)

4-6

stage 4

stage 5

stage 6

Early Endoderm
Early Mesoderm
Extraembryonic Mesoderm
Headfold
Primitive Streak
extraembryonic endoderm
extraembryonic mesoderm

Entry 2

GEISHA Id	TBX3.UApcr	Data Source	GEISHA ISH Analysis
Forward cDNA Template Primer	TGCTGTTAGAAACCACTCCAGGAC
Reverse cDNA Template Primer	ATTAACCCTCACTAAAGGTTGAAGGCTGTCTGCTCGTTGG	cDNA Template Length	1045
Forward cDNA Template Probe	show ANAAAATCGTCCGAAGTGGGGTTTTCTTTCTTCTGCCTCTCGTCGTACACCCGCATGGATTGCAGGGGTCAGCTGCTTC CTTTTTTCCCTCCTTCCATTCCCAGTGTCGCGAAAACCTTTGGCAAAGGGGTTGTTGTCAATTTTTAATTGAGTGATCT TATCATTCTGGTATGCGGTCACTGCGATGAATTCAGTCTCCGGGAACACGTAGGTCCGGAACGTGCTGTAGGGAAGCTT GAGAATATCGTTCGCTCGGACGATGTGGAAGCGGGGCTGGTACTTGTGCATGGAGTTTAAAATGGTAAATCCGTGCTTG TCGGAGATGTTGTTAGTGAGCTTCAGCTTGTGAAAGGTGACGACTTTGGACATCCATTGTTCTCCGGTGGCCGGGCTGT CCGGGTGGATGTACATTCTCTTTGGCATTTCAGGGTCAGCTTTGCCGGCTACCATCCACCGGGAATTATGGAATTTGTA CCTACAGTCGTCAGCCGCCACAATATCCATCAATAAAATGTACTTGGCCTTTTTATCCAGTCCAGTGCATCTCACTTTA AACGGAGGAAACATTCTCCTTCCCGATTTGGTGATCACCATCTCCGTGCCTCTTTTATGGAATTGTTCCCAAAGCTCTT TGGCTTCCANGTGCACTTTCNGGTCNTCTTCCACTTCTTCCTCTGGCTCCANANTTTTTAAANGCCNCANATGGNCTGC TGCCTGGNGNCCCANGNAANAAAANGNNANANCNNNCNCNNCNNCCCCCAC

Stage

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Location (click to highlight)

Comments (click to highlight)

7-12

stage 11

Amnion
Anterior Intestinal Portal
Ectoderm
Foregut
Hensen's Node
Lateral Plate Mesoderm
Neural Plate/Tube
Notochord

13-18

stage 13

stage 14

stage 15

Amnion
Anterior Intestinal Portal
Ear/Otic Placode
Ectoderm
Endoderm
Extraembryonic
Eye
Face Mesenchyme
Foregut
Head Mesenchyme
Hensen's Node
Intermediate Mesoderm
Lateral Plate Mesoderm
Neural Crest
Neural Plate/Tube
Notochord
Oral Pharynx
Pharyngeal Arches and Clefts
Somatic Mesoderm
Somites
Tail
extraembryonic ectoderm

19-24

stage 20

stage 23

Ear/Otic Placode
Eye
Face Mesenchyme
Leg Mesenchyme
Midgut
Nasal Placode/Nerve
Oral Pharynx
Pharyngeal Arches and Clefts
Somatic Mesoderm
Spinal Ganglia and Nerves
Valves
Wing Mesenchyme

Low level expression in heart valve and midgut.

25-26

stage 25

stage 26

Ear/Otic Placode
Eye
Leg Mesenchyme
Lung
Midgut
Nasal Placode/Nerve
Oral Pharynx
Pharyngeal Arches and Clefts
Somatic Mesoderm
Spinal Ganglia and Nerves
Valves
Wing Mesenchyme

Entry 3

GEISHA Id	Tbx3.Yamada.2000	Data Source	Publication
Complete cDNA Template Probe	show ATGGCTTATCATCCTTTTTTACCTCACCGGGCACCGGACTTTGCCATGAGTGCCGTGCTGGGACATCAGCCCCCCTTCT TCCCGGCCCTGGCTTTGCCCCCCAATGGGGCGGCCGCCCTCTCCCTCCCCGGCGCCCTGGCTAAGCCCATTATGGATCA GCTAGTGGGGGCTGCAGAGACTGCTATCCCCTTTTCTTCCCTGGGCCACCAGGCAGCAGCCCATCTGAGGCCTTTAAAA ACTCTGGAGCCAGAGGAAGAAGTGGAAGACGACCCGAAAGTGCACCTGGAAGCCAAAGAGCTTTGGGAACAATTCCATA AAAGAGGCACGGAGATGGTGATCACCAAATCGGGAAGGAGAATGTTTCCTCCGTTTAAAGTGAGATGCACTGGACTGGA TAAAAAGGCCAAGTACATTTTATTGATGGATATTGTGGCGGCTGACGACTGTAGGTACAAATTCCATAATTCCCGGTGG ATGGTAGCCGGCAAAGCTGACCCTGAAATGCCAAAGAGAATGTACATCCACCCGGACAGCCCGGCCACCGGAGAACAAT GGATGTCCAAAGTCGTCACCTTTCACAAGCTGAAGCTCACTAACAACATCTCCGACAAGCACGGATTTACCATTTTAAA CTCCATGCACAAGTACCAGCCCCGCTTCCACATCGTCCGAGCGAACGATATTCTCAAGCTTCCCTACAGCACGTTCCGG ACCTACGTGTTCCCGGAGACTGAATTCATCGCAGTGACCGCATACCAGAATGATAAGATCACTCAATTAAAAATTGACA ACAACCCCTTTGCCAAAGGTTTTCGCGACACTGGGAATGGAAGGAGGGAAAAAAGGAAGCAGCTGACCCTGCAATCCAT GCGGGTGTACGACGAGAGGCAGAAGAAAGAAAACCCCACTTCGGACGAATCGTCCAACGAGCAGACAGCCTTCAAGTGC TTCGCGCAGTCCTCCTGCCCCGCCGTGCCCGCCGTCGGCACCTCCAGCCTCAAAGATCTCTGTCCCAGCGAGGGTGACA GCGATGCCGACAGCAAAGACGACCCTTTGCTAGAAGCCAGCGAGTCGGGCAAAATCAGCACGACCACGGCCACCACCCC CGCGCCAGCCAGCTCCGGGGCGGCCGCGAGTGACGACCCTCGGGACAAAGGGGGCAGCCCTTCCAAAAGCCACTTCTTC CCCAGCGACTCGGCGACGAGCCGGAGCCGGGAGAGGACGGAAAAGGCCCCCCCGGACTCCAGGCACAGCCCGGCCACCA TCTCCTCCAGCAGCCGGGGGGGAGGCTTGAGCGGCGAGGAACTGAAAAGCCCCCTCCGGGACGGCCCTAAAGTAGACGA GAACCGGCTGCTGGCGGGCATCGCGCTGCTGCTGCACCCCGGGCAGTTCGCTATGGGGGGGGCTTTGTCCGGCAAGGCC GCGGGCATGGGTCTGCTGCTCGCCACGGTGTCGGGGGCTTCCGCCGGCGGCTCGGGACTGGACAGCACGGTGATGCCCA CAGAGGCGGCCCAGGGACTCTCGGGGGCATCAACATCCGCTCTGCCCTTCCACCTGCAGCAGCACGTCCTGGCCTCTCA GGGCTTGGCCATGTCCCCCTTCGGCAGCCTCTTCCCCTACCCCTACACCTACATGGCGGCGGCGGCGGCGGCTTCCAGC GCGGCCTCCAATTCTGTGCACCGGCATCCCTTCCTCAACGCCGTGCGGCCCCGGCTCCGCTACAGCCCCTACCCGTTGC CCGTGCCCCTGCCCGACGGCAGCAGCCTCCTCACCACCGCAATGCCCGGGGCCCTGGCCGCGACCTCCGGAGAGACCAA AGGCAGCGCTCTGGCCTCCAGTCCCGGCGCCGTGCCCCTGGACTCCGCCTCGGACCTCACCAGTCGCTCGTCCACGCTC TCCTCCGGCTCCGTATCCCTGTCCCCAAAGCTGGGAGCCGACAAGGAGGCGGCCACCAGCGAACTGCAGAACATCCAGC GCCTGGTCAGCGGCCTCGACCCCAAGCAGGACAGATCTCGCAGTGGCTCCCCGTTGCGGGCCGCACATCGTTGGAAAAT CAACCTACTGATAACGGAACACGAAGTGTATGTTTATGTCGCACAGGAAATCCCTTTCAACTCAACTGAGACACCAGAG ATAGAGGATTACTCGTTGTATAATCCCCCTAATCCTAATGAGATACGATATCGAAACGCATAA
Citation	Yamada M, Revelli JP, Eichele G, Barron M, Schwartz RJ. Expression of chick Tbx-2, Tbx-3, and Tbx-5 genes during early heart development: evidence for BMP2 induction of Tbx2. Dev Biol. 2000 Dec 1;228(1):95-105.
Copyright	Reprinted with permission from Elsevier. Copyright © 2000 Elsevier B.V. All rights reserved.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (XM_001234534).

Stage

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Location (click to highlight)

Comments (click to highlight)

4-6

stage 5

Lateral Plate Mesoderm

Precardiogenic mesoderm

7-12

stage 8

stage 10

Heart Tube
Primitive Streak
Veins

Precardiogenic mesoderm
Vitellin Veins

19-20

stage 20

Figure 1 compares expression patterns of Tbx2, Tbx3, Tbx5 and bmp2 in early chick embryos. Figure includes HH stages 5-8, 10, 11, 16, 19 and 20.

Entry 4

GEISHA Id	TBX3.Tumpel.2002	Data Source	Publication
Complete cDNA Template Probe	show ATGGCTTATCATCCTTTTTTACCTCACCGGGCACCGGACTTTGCCATGAGTGCCGTGCTGGGACATCAGCCCCCCTTCT TCCCGGCCCTGGCTTTGCCCCCCAATGGGGCGGCCGCCCTCTCCCTCCCCGGCGCCCTGGCTAAGCCCATTATGGATCA GCTAGTGGGGGCTGCAGAGACTGCTATCCCCTTTTCTTCCCTGGGCCACCAGGCAGCAGCCCATCTGAGGCCTTTAAAA ACTCTGGAGCCAGAGGAAGAAGTGGAAGACGACCCGAAAGTGCACCTGGAAGCCAAAGAGCTTTGGGAACAATTCCATA AAAGAGGCACGGAGATGGTGATCACCAAATCGGGAAGGAGAATGTTTCCTCCGTTTAAAGTGAGATGCACTGGACTGGA TAAAAAGGCCAAGTACATTTTATTGATGGATATTGTGGCGGCTGACGACTGTAGGTACAAATTCCATAATTCCCGGTGG ATGGTAGCCGGCAAAGCTGACCCTGAAATGCCAAAGAGAATGTACATCCACCCGGACAGCCCGGCCACCGGAGAACAAT GGATGTCCAAAGTCGTCACCTTTCACAAGCTGAAGCTCACTAACAACATCTCCGACAAGCACGGATTTACCATTTTAAA CTCCATGCACAAGTACCAGCCCCGCTTCCACATCGTCCGAGCGAACGATATTCTCAAGCTTCCCTACAGCACGTTCCGG ACCTACGTGTTCCCGGAGACTGAATTCATCGCAGTGACCGCATACCAGAATGATAAGATCACTCAATTAAAAATTGACA ACAACCCCTTTGCCAAAGGTTTTCGCGACACTGGGAATGGAAGGAGGGAAAAAAGGAAGCAGCTGACCCTGCAATCCAT GCGGGTGTACGACGAGAGGCAGAAGAAAGAAAACCCCACTTCGGACGAATCGTCCAACGAGCAGACAGCCTTCAAGTGC TTCGCGCAGTCCTCCTGCCCCGCCGTGCCCGCCGTCGGCACCTCCAGCCTCAAAGATCTCTGTCCCAGCGAGGGTGACA GCGATGCCGACAGCAAAGACGACCCTTTGCTAGAAGCCAGCGAGTCGGGCAAAATCAGCACGACCACGGCCACCACCCC CGCGCCAGCCAGCTCCGGGGCGGCCGCGAGTGACGACCCTCGGGACAAAGGGGGCAGCCCTTCCAAAAGCCACTTCTTC CCCAGCGACTCGGCGACGAGCCGGAGCCGGGAGAGGACGGAAAAGGCCCCCCCGGACTCCAGGCACAGCCCGGCCACCA TCTCCTCCAGCAGCCGGGGGGGAGGCTTGAGCGGCGAGGAACTGAAAAGCCCCCTCCGGGACGGCCCTAAAGTAGACGA GAACCGGCTGCTGGCGGGCATCGCGCTGCTGCTGCACCCCGGGCAGTTCGCTATGGGGGGGGCTTTGTCCGGCAAGGCC GCGGGCATGGGTCTGCTGCTCGCCACGGTGTCGGGGGCTTCCGCCGGCGGCTCGGGACTGGACAGCACGGTGATGCCCA CAGAGGCGGCCCAGGGACTCTCGGGGGCATCAACATCCGCTCTGCCCTTCCACCTGCAGCAGCACGTCCTGGCCTCTCA GGGCTTGGCCATGTCCCCCTTCGGCAGCCTCTTCCCCTACCCCTACACCTACATGGCGGCGGCGGCGGCGGCTTCCAGC GCGGCCTCCAATTCTGTGCACCGGCATCCCTTCCTCAACGCCGTGCGGCCCCGGCTCCGCTACAGCCCCTACCCGTTGC CCGTGCCCCTGCCCGACGGCAGCAGCCTCCTCACCACCGCAATGCCCGGGGCCCTGGCCGCGACCTCCGGAGAGACCAA AGGCAGCGCTCTGGCCTCCAGTCCCGGCGCCGTGCCCCTGGACTCCGCCTCGGACCTCACCAGTCGCTCGTCCACGCTC TCCTCCGGCTCCGTATCCCTGTCCCCAAAGCTGGGAGCCGACAAGGAGGCGGCCACCAGCGAACTGCAGAACATCCAGC GCCTGGTCAGCGGCCTCGACCCCAAGCAGGACAGATCTCGCAGTGGCTCCCCGTTGCGGGCCGCACATCGTTGGAAAAT CAACCTACTGATAACGGAACACGAAGTGTATGTTTATGTCGCACAGGAAATCCCTTTCAACTCAACTGAGACACCAGAG ATAGAGGATTACTCGTTGTATAATCCCCCTAATCCTAATGAGATACGATATCGAAACGCATAA
Citation	Tümpel S, Sanz-Ezquerro JJ, Isaac A, Eblaghie MC, Dobson J, Tickle C. Regulation of Tbx3 Expression by Anteroposterior Signalling in Vertebrate Limb Development. Dev Biol. 2002 Oct 15;250(2):251-62.
Copyright	Copyright © 2002 Elsevier Science (USA). All rights reserved.
Comments	According to authors, "Chicken Tbx3 was a gift (Ref.)." As information provided was insufficient to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI ( acc # XM_001234534).

Stage

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Location (click to highlight)

Comments (click to highlight)

13-18

stage 14

stage 17

Lateral Plate Mesoderm
Leg Mesenchyme
Tail
Wing
Wing Mesenchyme

19-24

stage 19

stage 20

stage 21

stage 22

stage 23

stage 24

Lateral Plate Mesoderm
Leg
Leg AER
Leg Mesenchyme
Limb Buds
Wing
Wing Mesenchyme

25-30

stage 26

stage 28

stage 30

Leg
Leg Muscles
Limb Buds
Wing Muscles

31-44

stage 44

Limb Buds

Entry 5

GEISHA Id	TBX2.SzaboRogers.2009	Data Source	Publication
Complete cDNA Template Probe	show GGGTTTGTGGGGTTTTTTTTAATTAATTTTTGTTGTCGATTTCCCTTCCTCTTCCAGTGCGAATTCGCCGGGCAGGAGA GGGGAGAAAAAAAAAAGATAAAAATAATCAAGCCGAACCGCACACTGATTTTTTATTATTGTTGTTATTATTGTCGTTT TTTTGTTATTATTATTTTTTTTTTAACAAAAGGGAATCCCTCTTTTTCTCCTGGATTTGTGGATGCACCGATGAGAGAT CCAGCCTTCCCAGGGACTGCCATGGCTTACCACCCCTTCCACGCTCCCCGGCCGGCCGATTTCCCCATGTCCGCTTTCC TCGCCGCCGCTCAGCCCTCCTTTTTCCCCGCTCTGGCTCTGCCCCCGGCGGCTCTGGCCAAGCCCATGCCGGACCCGGG GCTGGCCGGGGCGGCCGAGGCCGGGCTGCACGTCTCGGCTCTGGGCCACCACCACCAGGCAGCCCATCTGCGCTCCCTC AAGAGCCTGGAGCCCGAGGAGGAGGTGGAGGACGACCCCAAAGTGACGCTGGAAGCCAAAGAGCTTTGGGACCAATTCC ACAAGCTGGGCACCGAGATGGTGATCACCAAATCCGGGAGGAGGATGTTCCCCCCGTTCAAGGTGCGGGTGAGCGGCCT GGACAAGAAGGCCAAATACATTTTGCTCATGGATATAGTTGCGGCCGACGACTGCCGGTACAAATTCCACAACTCCCGC TGGATGGTGGCCGGGAAGGCCGACCCGGAGATGCCCAAACGCATGTACATCCACCCCGACAGCCCGGCCACCGGCGAGC AGTGGATGGCCAAACCCGTTGCCTTTCACAAACTCAAGCTCACCAACAACATCTCGGACAAACACGGCTTTACCATCCT GAACTCCATGCACAAATACCAGCCCCGCTTCCACATCGTGCGGGCCAACGACATCCTCAAGCTGCCCTACAGCACCTTC CGCACCTACGTGTTCCCCGAGACCGACTTCATCGCCGTCACCGCCTACCAGAACGACAAGATCACGCAGCTGAAAATCG ATAACAACCCCTTCGCCAAAGGCTTTCGGGACACGGGCAACGGCCGTCGGGAGAAGAGGAAGCAGCTCTCGCTGCCGTC ACTGCGGATGTACGAGGAGCCCTGCAAACCCGATCGAGACGGCGGCGAATCGGACGCGTCTTCCTGCGAACCATCGGCG GTGCGCGACGCTCTGCACTCCCCCGTGGGCCCCCTCCCCAGCCCCCTGCGCCTGAAGGGCAGTGGCAGAGAGGAGAAGC CGGGGGCTGACAGTGATGCGGAGGTGGAGAAGGTGTCCGAGGAGCGGCCAGTGGGCGGCAGCCCCGGTAGGGAGGACAC ATCACCCCGTGGCAGCCCACGGTGCACCGACGAGCGGGGCAAGGAGAGGCACAGCCCGGAGAAAGCCAAGGATGGAGCA TCCCCAGGGGACGGCCCCAGTGAGGGTCTGTTTGGCGCACGGGGCATGGAGAAGGACAAAGTGGAAGGGAGGAGGAAAG AGCCGGAGCAGGGCAAGAAGGACGCAGAGGGGGTCGGGCTGGGCAAGGAGGCCTTTGCCCCGCTGATGGTGCACACGGA CAGCCCTCCGCACCTGAGCGCCGGGCACCTGCAGAGCCTCGCGCTCTCTGGGCTCCACGGGCAGCAGTTCTTCAGCCCG CTGGGTGCTGGGCAGCCACTCTTCATCCACCCGGGACAGTTCGCCATGGCCCCCGGGGCTTTCTCCGCTATGGGCATGG GACATTTGCTGGCCTCGGTGACCGGCGGCGGCAGCCTGGAGAACGGGGCACTCTCGTCCACCCCAGGCGCAGCGGGGAC AGCCACCCCCTTCCCATTCCACCTCTCCCAGCACATGCTGGCTTCTCAGGGAATCCCGATGCCCACTTTCGGCGGCCTC TTCCCCTACCCCTACACCTACATGGCAGCAGCAGCAGCAGCCGCCTCGGCCATGCCGGCCACCAGCGCAGCCGCCGCCG CCGCCGGGCCGCTGTCCCGCAATCCCTTCCTGGGCAGCAGCCGCCCCCGCCTGCGCTTCAGCCCCTACCAGCTCCCGGT CAGCATCCCACCCAGCACCAACCTGCTCACCACCGGCCTCCCCTCCAGCCTCAACCCCAGCTCCGAGGGCTCCAAGGCG GGCAGCAGCCGTGAGCCCAGCCCCATCCCCGACGTGCACAAAGCCCATCGCCCCTCTGCCTCCCCTCCCAAAGGTTCCC TGAAGGAATCCCTCAACGAACTGCAGAACATCCAGAGACTGGTGAGCGGGCTGGAGAGCCAGCGGGAGCTGTCGCCCGG CAGGGAGTCCCCCAAGTGA
Citation	Szabo-Rogers HL, Geetha-Loganathan P, Whiting CJ, Nimmagadda S, Fu K, Richman JM. Novel skeletogenic patterning roles for the olfactory pit. Development. 2009 Jan;136(2):219-29. Epub 2008 Dec 4.
Copyright	Published by The Company of Biologists 2009. This material is protected by a copyright retained by the authors. Permission requested from Dr. Richman.
Comments	As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # XM_001235320.2).

Stage

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Location (click to highlight)

Comments (click to highlight)

13-15

stage 15

Ear/Otic Placode
Eye
Nasal Placode/Nerve
Pharyngeal Arches and Clefts

Entry 6

GEISHA Id	TBX3.Fisher.2008	Data Source	Publication
Complete cDNA Template Probe	show ATGAATATACCGATGAGAGATCCAGTGATCCCTGGGACAAGCATGGCTTATCATCCTTTTTTACCTCACCGGGCACCGG ACTTTGCCATGAGTGCCGTGCTGGGACATCAGCCCCCCTTCTTCCCGGCCCTGGCTTTGCCCCCCAATGGGGCGGCCGC CCTCTCCCTCCCCGGCGCCCTGGCTAAGCCCATTATGGATCAGCTAGTGGGGGCTGCAGAGACTGCTATCCCCTTTTCT TCCCTGGGCCACCAGGCAGCAGCCCATCTGAGGCCTTTAAAAACTCTGGAGCCAGAGGAAGAAGTGGAAGACGACCCGA AAGTGCACCTGGAAGCCAAAGAGCTTTGGGAACAATTCCATAAAAGAGGCACGGAGATGGTGATCACCAAATCGGGAAG GAGAATGTTTCCTCCGTTTAAAGTGAGATGCACTGGACTGGATAAAAAGGCCAAGTACATTTTATTGATGGATATTGTG GCGGCTGACGACTGTAGGTACAAATTCCATAATTCCCGGTGGATGGTAGCCGGCAAAGCTGACCCTGAAATGCCAAAGA GAATGTACATCCACCCGGACAGCCCGGCCACCGGAGAACAATGGATGTCCAAAGTCGTCACCTTTCACAAGCTGAAGCT CACTAACAACATCTCCGACAAGCACGGATTTGTGAGTCCTTTTCCTTCCCCCCACCCCGCCCTCCCCGGCCGCTCCGCA CCGCAGACCATTTTAAACTCCATGCACAAGTACCAGCCCCGCTTCCACATCGTCCGAGCGAACGATATTCTCAAGCTTC CCTACAGCACGTTCCGGACCTACGTGTTCCCGGAGACTGAATTCATCGCAGTGACCGCATACCAGAATGATAAGATCAC TCAATTAAAAATTGACAACAACCCCTTTGCCAAAGGTTTTCGCGACACTGGGAATGGAAGGAGGGAAAAAAGGAAGCAG CTGACCCTGCAATCCATGCGGGTGTACGACGAGAGGCAGAAGAAAGAAAACCCCACTTCGGACGAATCGTCCAACGAGC AGACAGCCTTCAAGTGCTTCGCGCAGTCCTCCTGCCCCGCCGTGCCCGCCGTCGGCACCTCCAGCCTCAAAGATCTCTG TCCCAGCGAGGGTGACAGCGATGCCGACAGCAAAGACGACCCTTTGCTAGAAGCCAGCGAGTCGGGCAAAATCAGCACG ACCACGGCCACCACCCCCGCGCCAGCCAGCTCCGGGGCGGCCGCGAGTGACGACCCTCGGGACAAAGGGGGCAGCCCTT CCAAAAGCCACTTCTTCCCCAGCGACTCGGCGACGAGCCGGAGCCGGGAGAGGACGGAAAAGGCCCCCCCGGACTCCAG GCACAGCCCGGCCACCATCTCCTCCAGCAGCCGGGGGGGAGGCTTGAGCGGCGAGGAACTGAAAAGCCCCCTCCGGGAC GGCCCTAAAGTAGACGAGAACCGGCTGCTGGGCAAAGAGCCCTTCGCCCCCCTCACGGTCCAGACCGACAGCACGGCGC ACCTGAGCCAGGGACATTTGCAGAACCTGGGGTTCCCCCCCGCCCTGGCCGGCCAGCAGTTCTTCAACCCGCTGGGGAG CGGGCATCCGCTGCTGCTGCACCCCGGGCAGTTCGCTATGGGGGGGGCTTTCTCCGGCATGGCCGCGGGCATGGGTCCG CTGCTCGCCACGGTGTCGGGGGCTTCCGCCGGCGGCTCGGGACTGGACAGCACGGTGATGGCCACGGCGGCGGCCCAGG GACTCTCGGGGGCATCCACAGCCGCTCTGCCCTTCCACCTGCAGCAGCACGTCCTGGCCTCTCAGGGCTTGGCCATGTC CCCCTTCGGCAGCCTCTTCCCCTACCCCTACACCTACATGGCGGCGGCGGCGGCGGCTTCCAGCGCGGCCTCCAATTCT GTGCACCGGCATCCCTTCCTCAACGCCGTGCGGCCCCGGCTCCGCTACAGCCCCTACCCGTTGCCCGTGCCCCTGCCCG ACGGCAGCAGCCTCCTCACCACCGCAATGCCCGGGGCCCTGGCCGCGACCTCCGGAGAGACCAAAGGCAGCGCTCTGGC CTCCAGTCCCGGCGCCGTGCCCCTGGACTCCGCCTCGGACCTCACCAGTCGCTCGTCCACGCTCTCCTCCGGCTCCGTA TCCCTGTCCCCAAAGCTGGGAGCCGACAAGGAGGCGGCCACCAGCGAACTGCAGAACATCCAGCGCCTGGTCAGCGGCC TCGACCCCAAGCAGGACAGATCTCGCAGTGGCTCCCCGTAG
Citation	Fisher ME, Clelland AK, Bain A, Baldock RA, Murphy P, Downie H, Tickle C, Davidson DR, Buckland RA. Integrating technologies for comparing 3D gene expression domains in the developing chick limb. Dev Biol. 2008 May 1;317(1):13-23. Epub 2008 Feb 7.
Copyright	Copyright © 2008 Elsevier Inc.
Comments	As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc #XM_001234534.2 ).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

19-22

stage 22

Ear/Otic Placode
Limb Buds
Pharyngeal Arches and Clefts
Pineal Gland
Trunk Mesenchyme

double labeled

Entry 7

GEISHA Id	Tbx3.Gibson-Brown.1998	Data Source	Publication
Complete cDNA Template Probe	show ATGAATATACCGATGAGAGATCCAGTGATCCCTGGGACAAGCATGGCTTATCATCCTTTTTTACCTCACCGGGCACCGG ACTTTGCCATGAGTGCCGTGCTGGGACATCAGCCCCCCTTCTTCCCGGCCCTGGCTTTGCCCCCCAATGGGGCGGCCGC CCTCTCCCTCCCCGGCGCCCTGGCTAAGCCCATTATGGATCAGCTAGTGGGGGCTGCAGAGACTGCTATCCCCTTTTCT TCCCTGGGCCACCAGGCAGCAGCCCATCTGAGGCCTTTAAAAACTCTGGAGCCAGAGGAAGAAGTGGAAGACGACCCGA AAGTGCACCTGGAAGCCAAAGAGCTTTGGGAACAATTCCATAAAAGAGGCACGGAGATGGTGATCACCAAATCGGGAAG GAGAATGTTTCCTCCGTTTAAAGTGAGATGCACTGGACTGGATAAAAAGGCCAAGTACATTTTATTGATGGATATTGTG GCGGCTGACGACTGTAGGTACAAATTCCATAATTCCCGGTGGATGGTAGCCGGCAAAGCTGACCCTGAAATGCCAAAGA GAATGTACATCCACCCGGACAGCCCGGCCACCGGAGAACAATGGATGTCCAAAGTCGTCACCTTTCACAAGCTGAAGCT CACTAACAACATCTCCGACAAGCACGGATTTACCATTTTAAACTCCATGCACAAGTACCAGCCCCGCTTCCACATCGTC CGAGCGAACGATATTCTCAAGCTTCCCTACAGCACGTTCCGGACCTACGTGTTCCCGGAGACTGAATTCATCGCAGTGA CCGCATACCAGAATGATAAGATCACTCAATTAAAAATTGACAACAACCCCTTTGCCAAAGGTTTTCGCGACACTGGGAA TGGAAGGAGGGAAAAAAGGAAGCAGCTGACCCTGCAATCCATGCGGGTGTACGACGAGAGGCAGAAGAAAGAAAACCCC ACTTCGGACGAATCGTCCAACGAGCAGACAGCCTTCAAGTGCTTCGCGCAGTCCTCCTGCCCCGCCGTGCCCGCCGTCG GCACCTCCAGCCTCAAAGATCTCTGTCCCAGCGAGGGTGACAGCGATGCCGACAGCAAAGACGACCCTTTGCTAGAAGC CAGCGAGTCGGGCAAAATCAGCACGACCACGGCCACCACCCCCGCGCCAGCCAGCTCCGGGGCGGCCGCGAGTGACGAC CCTCGGGACAAAGGGGGCAGCCCTTCCAAAAGCCACTTCTTCCCCAGCGACTCGGCGACGAGCCGGAGCCGGGAGAGGA CGGAAAAGGCCCCCCCGGACTCCAGGCACAGCCCGGCCACCATCTCCTCCAGCAGCCGGGGGGGAGGCTTGAGCGGCGA GGAACTGAAAAGCCCCCTCCGGGACGGCCCTAAAGTAGACGAGAACCGGCTGCTGGGCAAAGAGCCCTTCGCCCCCCTC ACGGTCCAGACCGACAGCACGGCGCACCTGAGCCAGGGACATTTGCAGAACCTGGGGTTCCCCCCCGCCCTGGCCGGCC AGCAGTTCTTCAACCCGCTGGGGAGCGGGCATCCGCTGCTGCTGCACCCCGGGCAGTTCGCTATGGGGGGGGCTTTCTC CGGCATGGCCGCGGGCATGGGTCCGCTGCTCGCCACGGTGTCGGGGGCTTCCGCCGGCGGCTCGGGACTGGACAGCACG GTGATGGCCACGGCGGCGGCCCAGGGACTCTCGGGGGCATCCACAGCCGCTCTGCCCTTCCACCTGCAGCAGCACGTCC TGGCCTCTCAGGGCTTGGCCATGTCCCCCTTCGGCAGCCTCTTCCCCTACCCCTACACCTACATGGCGGCGGCGGCGGC GGCTTCCAGCGCGGCCTCCAATTCTGTGCACCGGCATCCCTTCCTCAACGCCGTGCGGCCCCGGCTCCGCTACAGCCCC TACCCGTTGCCCGTGCCCCTGCCCGACGGCAGCAGCCTCCTCACCACCGCAATGCCCGGGGCCCTGGCCGCGACCTCCG GAGAGACCAAAGGCAGCGCTCTGGCCTCCAGTCCCGGCGCCGTGCCCCTGGACTCCGCCTCGGACCTCACCAGTCGCTC GTCCACGCTCTCCTCCGGCTCCGTATCCCTGTCCCCAAAGCTGGGAGCCGACAAGGAGGCGGCCACCAGCGAACTGCAG AACATCCAGCGCCTGGTCAGCGGCCTCGACCCCAAGCAGGACAGATCTCGCAGTGGCTCCCCGTAG
Citation	Gibson-Brown JJ, I Agulnik S, Silver LM, Papaioannou VE. Expression of T-box genes Tbx2-Tbx5 during chick organogenesis. Mech Dev. 1998 Jun;74(1-2):165-9.
Copyright	Copyright © 1998 Elsevier Science Ireland Ltd.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_001270878).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

13-18

stage 15

Ear/Otic Placode
Eye
Leg
Somites
Wing

19-24

stage 21

Allantois
Dermomyotome
Lateral Plate Mesoderm
Leg
Neural Plate/Tube
Pharyngeal Arches and Clefts
Wing

maxilla
sp, somatopleure

31-44

stage 44

Entry 8

GEISHA Id	TBX3.Trevers.2023	Data Source	GEISHA ISH Analysis
Complete cDNA Template Probe	show CAGACTCACAGGGAATTCTCAGAGCTGAGAGGCTCCTTCTCTCCCTCTCCTCTCTCCTCTTTCTCTCTTTCTCCCCCCC TTCTCCTCCTTTCTCTCTCTTTCCCTCTCTTCCTCCCTCTCTCCTTTGCTGGAGTGTTGCTGGAGAGGAGACAAGAGTA TCATTCTTCCAGATTTTTTTTTTTTTAAGGCAGAGTGAAAGAGAAAGAGAAGGGAAAGGAAAAAAAAAATAGGAGGAGG GTGAAAGAAAGAAGAGATCCAGGGCACTGTGACCAGCTCCTGCTCGGAGCGGGGGAAGGCGAAGCGGAAACGAGATTTC CCTACAAGTTTTGCTGCTGCCGCTGCCTGAAGGTTGCTGAGGAGCCTTCCCCGCTCGGCGAGGGGGGTGGGTTTGTTCG CTTCTCTCTGCTTTCCCTCCCTCCCCAGCCTCTGCTCTGCAGCCTGCCCGTACGGAGGAAAGGTGGAGGGGTGGGGGGG AGGGGGGGGACACAGCCGACCCAAAAAGAGAGCCCGGCTTCCAGCCGCCACCCTCCGCGACGGAAGAAGAGAAGAGGGA CTGAGAGCACGAGAAAAAAGAAGAAGAGGAAAAAAAGGATCTCGGCTTGTCCAGCCCTTCCGCGGCAACGGGAGCACGC AGCGAACCCGGTGGATTTTTTTCTCCCCTTCTTCGGCACTGCTTTTCAAGCGCAAGGACTTCCACTCGGAAAAGAAAAA AAAAAAGCCGCAGAGAGAGAACAACAACACAGACAGCAAGACGAATAATGAACAATCCTGTTACCCCGCTGTCCCGAGG GCCGAGGATGTGCCCCGGCTCGGGAAGTTGTAGGCTGTAGAAGTTCTGCCTCTCCCCCATGTACTGTGCTGTTTAGAGC TTGTTTCCCCCCACTTTTTTTTTTTTTTTTTTTCCTTTTTGGTGCTTAATCGTTGTTACTGTTATTATCTTAATTTTTC TTCTTCATGATGTGCTGTTAGAAACCACTCCAGGACTACTCCAGCAGTAGGAAGACCGAGGAGTGGAGTGGATGAATAT ACCGATGAGAGATCCAGTGATCCCTGGGACAAGCATGGCTTATCATCCTTTTTTACCTCACCGGGCACCGGACTTTGCC ATGAGTGCCGTGCTGGGACATCAGCCCCCCTTCTTCCCGGCCCTGGCTTTGCCCCCCAATGGGGCGGCCGCCCTCTCCC TCCCCGGCGCCCTGGCTAAGCCCATTATGGATCAGCTAGTGGGGGCTGCAGAGACTGCTATCCCCTTTTCTTCCCTGGG CCACCAGGCAGCAGCCCATCTGAGGCCTTTAAAAACTCTGGAGCCAGAGGAAGAAGTGGAAGACGACCCGAAAGTGCAC CTGGAAGCCAAAGAGCTTTGGGAACAATTCCATAAAAGAGGCACGGAGATGGTGATCACCAAATCGGGAAGGAGAATGT TTCCTCCGTTTAAAGTGAGATGCACTGGACTGGATAAAAAGGCCAAGTACATTTTATTGATGGATATTGTGGCGGCTGA CGACTGTAGGTACAAATTCCATAATTCCCGGTGGATGGTAGCCGGCAAAGCTGACCCTGAAATGCCAAAGAGAATGTAC ATCCACCCGGACAGCCCGGCCACCGGAGAACAATGGATGTCCAAAGTCGTCACCTTTCACAAGCTGAAGCTCACTAACA ACATCTCCGACAAGCACGGATTTACCATTTTAAACTCCATGCACAAGTACCAGCCCCGCTTCCACATCGTCCGAGCGAA CGATATTCTCAAGCTTCCCTACAGCACGTTCCGGACCTACGTGTTCCCGGAGACTGAATTCATCGCAGTGACCGCATAC CAGAATGATAAGATCACTCAATTAAAAATTGACAACAACCCCTTTGCCAAAGGTTTTCGCGACACTGGGAATGGAAGGA GGGAAAAAAGGAAGCAGCTGACCCTGCAATCCATGCGGGTGTACGACGAGAGGCAGAAGAAAGAAAACCCCACTTCGGA CGAATCGTCCAACGAGCAGACAGCCTTCAAGTGCTTCGCGCAGTCCTCCTGCCCCGCCGTGCCCGCCGTCGGCACCTCC AGCCTCAAAGATCTCTGTCCCAGCGAGGGTGACAGCGATGCCGACAGCAAAGACGACCCTTTGCTAGAAGCCAGCGAGT CGGGCAAAATCAGCACGACCACGGCCACCACCCCCGCGCCAGCCAGCTCCGGGGCGGCCGCGAGTGACGACCCTCGGGA CAAAGGGGGCAGCCCTTCCAAAAGCCACTTCTTCCCCAGCGACTCGGCGACGAGCCGGAGCCGGGAGAGGACGGAAAAG GCCCCCCCGGACTCCAGGCACAGCCCGGCCACCATCTCCTCCAGCAGCCGGGGGGGAGGCTTGAGCGGCGAGGAACTGA AAAGCCCCCTCCGGGACGGCCCTAAAGTAGACGAGAACCGGCTGCTGGGCAAAGAGCCCTTCGCCCCCCTCACGGTCCA GACCGACAGCACGGCGCACCTGAGCCAGGGACATTTGCAGAACCTGGGGTTCCCCCCCGCCCTGGCCGGCCAGCAGTTC TTCAACCCGCTGGGGAGCGGGCATCCGCTGCTGCTGCACCCCGGGCAGTTCGCTATGGGGGGGGCTTTCTCCGGCATGG CCGCGGGCATGGGTCCGCTGCTCGCCACGGTGTCGGGGGCTTCCGCCGGCGGCTCGGGACTGGACAGCACGGTGATGGC CACGGCGGCGGCCCAGGGACTCTCGGGGGCATCCACAGCCGCTCTGCCCTTCCACCTGCAGCAGCACGTCCTGGCCTCT CAGGGCTTGGCCATGTCCCCCTTCGGCAGCCTCTTCCCCTACCCCTACACCTACATGGCGGCGGCGGCGGCGGCTTCCA GCGCGGCCTCCAATTCTGTGCACCGGCATCCCTTCCTCAACGCCGTGCGGCCCCGGCTCCGCTACAGCCCCTACCCGTT GCCCGTGCCCCTGCCCGACGGCAGCAGCCTCCTCACCACCGCAATGCCCGGGGCCCTGGCCGCGACCTCCGGAGAGACC AAAGGCAGCGCTCTGGCCTCCAGTCCCGGCGCCGTGCCCCTGGACTCCGCCTCGGACCTCACCAGTCGCTCGTCCACGC TCTCCTCCGGCTCCGTATCCCTGTCCCCAAAGCTGGGAGCCGACAAGGAGGCGGCCACCAGCGAACTGCAGAACATCCA GCGCCTGGTCAGCGGCCTCGACCCCAAGCAGGACAGATCTCGCAGTGGCTCCCCGTAGCCGCCAGCTCATTTCAAACCA GTCTCGCAATGCACTTTGTTTGAAAGAAACCACATCCTCCATCCCGCGAAGCCTTTCAGCCCCCAGCCCCCCCCCCCCC CCCCCTTCTCTCCCCTACCCCCTTTTTATTTTATTGTTTGTTTGTTTGTTTTTTAATTTTTAAGTTTTATTTTTAATAT AAATCACCCGGCGTCGTGTGGGCGCTGATCAGCAAAAAGTGTCGAGCTGGAGGAGGGAGGGGGGGGGGTGGGGGGACGG GGGAGGGCCGGGCTGGGAGCCGGGCCGGGGGCTGCCGCACCGAGGGGACGCCGGAATGCGTGTCCCACCACCCCCTTCT TTTCTTCACTCTTAAAATAAATAAATAACTAAATAAATAGCGGGGGGAGGGGGGGGGGGAAGAAAAAAAAAAAGGAAAA AAAAAAGAAAAAAAGAAAAAGAAAAAAAAAACCGCCTGGAAACAAAATAAAGCGAAGCAAAACACCGAACGGACGTATA AATAAAAGAAAGTAAGCAAAGAGATTTTTTTTTTTCCTAAAGAAAACTGTATAAGTAACTCTCACATCGGCCATTCGCC AGTTGTTTCCTGGGCGGGTTGGTAGCGACGGCCCTCTGCATCGATATTAAGGGAAGCTGTGTGTTTAAAATATTATCGT GATGTCTGAGAGCCACTCGGTGGCTTTTTTTGCATGTTCCGTAGTAGTCTGCTTTTTTAGGGGGGGGGGGGGCTATGTT TTTATTTCGTTGGGTTTTCGTTGTTTATTTCTGATGCTCGTTTCGAATCCCAGGGACAAAATAATAATAATAATAATGA TAATGATAATAATAATAAAAACGAAAAGAAGACCCTTTTCCCTCTTCCTTAAAGACCCTCCCCGTAGCAACAACAATAA GAAGCGTAGCTGGAAAGAAAAAAAAAAAAGAAGTGGATTTATTTTATCTAAAAACCTCTGTAGCTCGACTGTAGGTTTA TCACAGCTTTCCCTCTTTCATTGTATATGCAATAACAAGGTTTAAACGCTGAGGAGAAGAAAAAAAAGCGGACACTATT ATTAAAGCAAAGTATTTATGTAATTATTTGATAACTCTTGTAAATACGTGGAATATGAATACTCGAAATTAAACTTTAA TTTATTGACGTTGTACATATCTCTGTAAA
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_001270878).