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 | KIT
KIT proto-oncogene receptor tyrosine kinase | The human orthologue of this gene is associated
with the following human diseases: |
| Gene | | Official Symbol | KIT | | Official Full Name | KIT proto-oncogene receptor tyrosine kinase | | CGNC ID | 10414 | | also known as | SCFR, mast/stem cell growth factor receptor Kit|c-kit|proto-oncogene c-Kit|proto-oncogene tyrosine-protein kinase Kit|tyrosine-protein kinase Kit|v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, SCFR, Proto-oncogene tyrosine-protein kinase Kit, c-kit, Mast/stem cell growth factor receptor precursor | | gene type | protein-coding |
| | Genomic Map | | | Sequence Information | | | Gene Expression | | | Orthology | | | Gene Ontology | | Molecular Function | ATP binding, cytokine binding, metal ion binding, protease binding, protein homodimerization activity, more...receptor signaling protein tyrosine kinase activity, stem cell factor receptor activity | | Biological Process | actin cytoskeleton reorganization, activation of MAPK activity, more...cellular response to thyroid hormone stimulus, dendritic cell cytokine production, detection of mechanical stimulus involved in sensory perception of sound, digestive tract development, ectopic germ cell programmed cell death, embryonic hemopoiesis, erythrocyte differentiation, erythropoietin-mediated signaling pathway, Fc receptor signaling pathway, glycosphingolipid metabolic process, immature B cell differentiation, inflammatory response, lamellipodium assembly, lymphoid progenitor cell differentiation, male gonad development, mast cell chemotaxis, mast cell cytokine production, mast cell degranulation, mast cell differentiation, megakaryocyte development, melanocyte adhesion, melanocyte differentiation, melanocyte migration, myeloid progenitor cell differentiation, negative regulation of programmed cell death, ovarian follicle development, positive regulation of cell proliferation, positive regulation of gene expression, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of tyrosine phosphorylation of Stat1 protein, positive regulation of tyrosine phosphorylation of Stat3 protein, positive regulation of tyrosine phosphorylation of Stat5 protein, protein autophosphorylation, regulation of cell shape, regulation of developmental pigmentation, response to radiation, spermatid development, stem cell differentiation, T cell differentiation | | Cellular Component | external side of plasma membrane, extracellular space, integral component of membrane, mast cell granule, more...nucleus |
| | Links to other databases | |
No expression data available.
| | Data from NCBI Unigene EST Profile
Unigene ID: Gga.606 |
MouseFrogFruit FlyZebra FinchZebrafish |
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