GEISHA - A Chicken Embryo Gene Expression Database
Browse By
- Anatomical Location
- Stage
- Gene Name
- GEISHA ID
- Multiple Parameters
Search
- Quick Search
Data Class
Enter Text:
go
- Gene Family QuickSearch
Transcription Factors
Growth Factors
Receptors
MicroRNAs
- Human Disease Gene Search
Documents
- Downloads
- Protocols
- About GEISHA
- Contact Us
Resources
- Transgenic Birds
- Model Organism Databases
- Gene Expression Databases
- Genomic Resources
- Anatomical Atlases
- Chicken Stage Series
_

RB1
retinoblastoma 1

The human orthologue of this gene is associated
with the following human diseases:
Gene
Official SymbolRB1
Official Full Nameretinoblastoma 1
CGNC ID12759
also known asretinoblastoma-associated protein|p104|pRb|rb|retinoblastoma 1 (including osteosarcoma), retinoblastoma 1 , RB1
gene typeprotein-coding
Genomic Map
 Ensembl
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
RNANM_204419
PolypeptideNP_989750
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST ProfileGga.2986
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly
Human5925ENSG00000139687MIM:109800MIM:614041
Mouse19645ENSMUSG00000022105All phenotypic alleles (22):Targeted, knock-out(10) Targeted, other(12) MGI:97874
Xenopus1004931141018164
Zebrafish777733ENSDARG00000006782ZDB-GENE-040428-1ZFIN:ZDB-GENE-040428-1
Gene Ontology
Molecular FunctionDNA binding
Biological Processcell cycle, chromatin modification, regulation of cell cycle, more...regulation of transcription from RNA polymerase II promoter, transcription, DNA-templated, viral process
Cellular Componentnucleus
Links to other databases
Entrez Gene386582
Ensembl GeneENSGALG00000016997
KEGGgga:386582

Entry 1

GEISHA IdRetinoblastoma.Wagner.2001Data SourcePublication
Complete cDNA Template Probeshow
GAATTCTCTTGGTGTTGTAGCCTCAAATGGATTACCAGAGGTTGACGTTCTCTCAAAACAATATGATGAGCTTTATCTC
AAAAACAAAGATATAGATGCAAGATTATTTCTGGATCATGATGAAACTCTACAGCCTGATGTTATAGCATGCTCACAGT
TGGAAAGAACACCACGAAAAAATAACCCAGATGAGGAGGTTAATCATGTACTTCCACAGACTCCTGTTCGAGCTGCAAT
GAATACTATTCAGCAGTTGATGATGATTTTGAACTCAGCAACTGATAAACCATCAGATACTCTCATTGCATATTTCAAT
AATTGCACAGTGAACCCTGAAGACAGCATCCTGAAAAGAGTAGAAAGTCTTGGCCACATCTTCAAAAAGAAATTTGCTG
AAGCAGTTGGACAGGGATGTGCTGAGATTGGCTCACAGAGATACCAGCTTGGAGTACGGCTGTATTACAGAGTAATGGA
GTCTATGCTGAAGTCGGAAGAAGAGCGCCTCTCAGTGCACAATTTTAGCAAACTTCTGAATGATAACATCTTCCACACA
TCTCTTCTGGCATGTGCTCTTGAAATTGTCATGGCTACCTATGGCAGAACTGCTTCACAAAGTGATGGTACCAGTGCTG
AAACAGACTTGTCTTTCCCATGGATTCTCAACGTATTTGATTTAAAAGCTTTTGACTTCTACAAGGTGATTGAAAGTTT
CATTAAAGTGGAGCCAAGCCTAACGAGGGACATGATAAAGCATCTAGAACGCTGTGAACATCGCATTATGGAATCTCTT
GCTTGGCAATCTGATTCACCTCTGTTCGATCTTATCAAGCAGTCAAAAGAACGAGAAGGTCAGACCGATCAGCCTGAGC
CCACTTCCACCCTAAATCTGCCTCTCCAGCACAACCACACTGCAGCAGATCTGTATCTTTCTCCTGTGAGATCTCCTAA
GAAGAAAGCATCTGGACACCCTCAAAGTGGTACTTCTAATCCAGATGCTCAGCCATCTGCGACCTCACAAACACAGAAG
CCACAGAAATCTACCTCCCTCTCTCTGTTCTACAAAAAAGTGTTTCGACTGGCCTATCTTCGATTGCATACCCTGTTCT
TTCGGCTTCTCTCCGAACATCCTGACCTGGAGCCGTTGATCTGGACCCTCTTCCAGCACACACTGCAAAATGAGTCTGA
GCTTATGAGAGACAGGCACTTGGACCAGATCATGATGTGTTCCATGTATGGCATATGCAAAGTAAAGAATGTGGATCTT
AGATTTAAAACAATAGTTTCTGCATACAAAGAGCTGCCCAATACAAATCAAGAGACTTTCAAACGTGTTCTTATCAGGG
AAGAGCAGTACGACTCCATTATAGTCTTCTACAACTTAGTGTTCATGCAGAAGCTGAAGACAAACATCCTGCAGTATGC
CTCCAACAGGCCTCCTACGCTGTCACCTATCCCACACATTCCTCGCAGCCCCTACCAGTTTTCCAATTCTCCTCGGCGT
GTCCCTGCGGGCAATAACATCTACATCTCACCCTTGAAGAGCCCTTACAAGTTCTCTGATGGGTTTCATTCTCCCACAA
AGATGACTCCGAGGTCCAGAATTCTGGTGTCAATTGGTGAAACGTTTGGGACTTCTGAAAAGTTTCAAAAAATAAACCA
GATGGTGTGCAAC
CitationWagner M, Miles K, Siddiqui MA. Early developmental expression pattern of retinoblastoma tumor suppressor mRNA indicates a role in the epithelial-to-mesenchyme transformation of endocardial cushion cells. Dev Dyn. 2001 Mar;220(3):198-211.
CopyrightCopyright © 2001 Wiley-Liss, Inc.
Commentsno expression reported at stage 14 or below.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
13-18
stage 16
stage 16
stage 17
stage 17
stage 18
stage 18
Endocardium
isolated heart

Entry 2

GEISHA IdRB.Marx.2010Data SourcePublication
Complete cDNA Template Probeshow
AGCGGAGCCCCTTGGTGGCCGCTTGTACGGCGGGGGCCCGACGGTCACCATGCCGCCCAAGCCCCTTCGCAGGGCGGGC
GCCGCCAGGAGTCAGCGCACCAGCCCCGAGGGCGGCGCCGGCACCGCCTCACCGCCCGGCGGCACCCGGCTGGAAGTGG
GGGAAGCGGAGTTCGTGGCTCTGTGCGATGCGCTGAAGGCGCCGGACAGCGTGAGGGAGAAGGCCTGGATGACGTACCA
GAGCTTGGCGGCCGCCGACGGGGCTTCGGCTTATAACAAAAAGAAGAAGGAAACATGGGGAGTCTGTATCTTTATTGTA
GCAATTGATCTGGATGAAATGACATTCACTTTTACAGAGCTGCTGAAAAGTTTAAGCATAAGCGTGTGCACATTTTTTC
AGTTTCTCAAAGAGGTGGATGTTAACATGGATACTGTAAGCACTAAAGTTGATAGCACTGTATCAAGGCTGAAAAAGAA
ATACGATGTCTTACTTGCACTGTATCACAAGTTCGAAAGGACTTGTGGCCTTATTTATCTGGAGCAACCCAGTAGTGAG
ATTTCTGCTGAACTCAGTTCTGTATTAGTCCTAAAAAATTACTGGATTACTTTTTTGCTGGCAAAAGGTAAAGTGTTGC
AAATGGAAGATGACCTCGTGATCTCTTTCCAGTTGTTGCTGTGCGTCTTAGATTATTTTATCAAACTGTCACCTCCTGC
TATGCTCAAGGAACCATACAAGTCTGCTGTGACTGCACTGACTGTTAATGGTTCAACTCGAACCCCACGAAGAGGTCAG
AACAGGAATGCACGCGCTTCAAAGCAAATTGATACAGATACAAAAGTTATTGAAATCCTTTGTAAAGAGCATGATTGTA
ATTTAGACGAGGTAAAAAATGTGTATTTCACAAGCTTTATTCCTTTCTTGAATTCTCTTGGTGTTGTAGCCTCAAATGG
ATTACCAGAGGTTGACGTTCTCTCAAAACAATATGATGAGCTTTATCTCAAAAACAAAGATATAGATGCAAGATTATTT
CTGGATCATGATGAAACTCTACAGCCTGATGTTATAGCATGCTCACAGTTGGAAAGAACACCACGAAAAAATAACCCAG
ATGAGGAGGTTAATCATGTACTTCCACAGACTCCTGTTCGAGCTGCAATGAATACTATTCAGCAGTTGATGATGATTTT
GAACTCAGCAACTGATAAACCATCAGATACTCTCATTGCATATTTCAATAATTGCACAGTGAACCCTGAAGACAGCATC
CTGAAAAGAGTAGAAAGTCTTGGCCACATCTTCAAAAAGAAATTTGCTGAAGCAGTTGGACAGGGATGTGCTGAGATTG
GCTCACAGAGATACCAGCTTGGAGTACGGCTGTATTACAGAGTAATGGAGTCTATGCTGAAGTCGGAAGAAGAGCGCCT
CTCAGTGCACAATTTTAGCAAACTTCTGAATGATAACATCTTCCACACATCTCTTCTGGCATGTGCTCTTGAAATTGTC
ATGGCTACCTATGGCAGAACTGCTTCACAAAGTGATGGTACCAGTGCTGAAACAGACTTGTCTTTCCCATGGATTCTCA
ACGTATTTGATTTAAAAGCTTTTGACTTCTACAAGGTGATTGAAAGTTTCATTAAAGTGGAGCCAAGCCTAACGAGGGA
CATGATAAAGCATCTAGAACGCTGTGAACATCGCATTATGGAATCTCTTGCTTGGCAATCTGATTCACCTCTGTTCGAT
CTTATCAAGCAGTCAAAAGAACGAGAAGGTCAGACCGATCAGCCTGAGCCCACTTCCACCCTAAATCTGCCTCTCCAGC
ACAACCACACTGCAGCAGATCTGTATCTTTCTCCTGTGAGATCTCCTAAGAAGAAAGCATCTGGACACCCTCAAAGTGG
TACTTCTAATCCAGATGCTCAGCCATCTGCGACCTCACAAACACAGAAGCCACAGAAATCTACCTCCCTCTCTCTGTTC
TACAAAAAAGTGTTTCGACTGGCCTATCTTCGATTGCATACCCTGTTCTTTCGGCTTCTCTCCGAACATCCTGACCTGG
AGCCGTTGATCTGGACCCTCTTCCAGCACACACTGCAAAATGAGTCTGAGCTTATGAGAGACAGGCACTTGGACCAGAT
CATGATGTGTTCCATGTATGGCATATGCAAAGTAAAGAATGTGGATCTTAGATTTAAAACAATAGTTTCTGCATACAAA
GAGCTGCCCAATACAAATCAAGAGACTTTCAAACGTGTTCTTATCAGGGAAGAGCAGTACGACTCCATTATAGTCTTCT
ACAACTTAGTGTTCATGCAGAAGCTGAAGACAAACATCCTGCAGTATGCCTCCAACAGGCCTCCTACGCTGTCACCTAT
CCCACACATTCCTCGCAGCCCCTACCAGTTTTCCAATTCTCCTCGGCGTGTCCCTGCGGGCAATAACATCTACATCTCA
CCCTTGAAGAGCCCTTACAAGTTCTCTGATGGGTTTCATTCTCCCACAAAGATGACTCCGAGGTCCAGAATTCTGGTGT
CAATTGGTGAAACGTTTGGGACTTCTGAAAAGTTTCAAAAAATAAACCAGATGGTGTGCAACAGCGAGAGCCACGTAAA
GCGCAGTGCGGAGCCCAGCGATGCCCCCAAGCCACTGAAGAGGCTGCGCTTCGATATAGAAGGGCAGGACGAGGCAGAT
GGAGGCAAACACCTTCCCCAGGAGTCCAAGTTCCAACAAAAGCTTGCAGAAATGACATCTACTCGAACAAGAATGCAGA
AGCAGAAACTGAATGATGGAAACGATACCTCAGCCAACGAAGAAAAGTGAGATTCTCCTCAGGACCAGGGGCTGCTGCA
GGCCCTCCCAGCTTTTGTTTTACTGCCTTCATTCACTGAGTTGCTTCTTCAGTCGCTTTTATCCCAAACCAATAGTTGA
AAACCCTTGGACTTTATTTTCTTCAAGGTTTTTCACGATACTTTGCCTTATGATGTAGCATGTATGCGATGTAAGCCAC
TGAATTTAATTTATATATTTTCGGGGGATTTTAAAAAGCAGCTTGGGAAGTGTCTTAGTTTGCTATTGCAGCGTTACTG
ATTGAAGCCAGTTCAATCTACCTGGATTGAATATTTTCTGTCTCAAGACAAAACGTTAGCTAGGGATCTGAAGTGCACT
AATTTTACTTCTTAGATTTCATTTTAATGTCGGATCTCAAAGCATTATTTGCAAGTATTGAAAATGAGGGGTCAGATGC
CGCAAGGATTTCTGTCTCTGTGTGTAATTAACACATCCAATTCCCATTAACTTAGCTGCACAGCAGCCGTGCAGGGTCA
GGCTCTCCCCGCAGAAGCAGGAAGCAGTGAGCACGTCGTGTTAGCGGTACTACTGAAAGCAGTGAGCTGTGCTGCACCT
CAGGTACGTCCCGTTCTGCAGTCCCCCAGCTCTCACCCCACACATTTCAGAGGGCCCACGTTGAATTTCATTGAATCTC
ACAGAGGTTGAGTCCCACGAAGCAAAAAGGCGCATTCCCAAATGCAAAGTACCACGTTGTGCACTTTCGTATCTCGGAA
AACCTCGATTTAAGAAAACACAAAGTAGAACACCCCCAACCTACATCACACCTCGCACACAGAAGATGGCAAAGGTCTC
ACAATGTAGGATTCTCTTGAAGTGATTTCTACAGGTGTCCATGTGGCCGAACGTCACAGCACGAAGCTGTGTGCCTGAG
GCGGTGCCTTACCCAAAAGGCAGAGCTCAATGGGCAACTTGGGAGCAAACGTTTTTAAGTGTATTTATAAGTTATGGAC
TCAGATAGTGGATTTTTTTTTTCTTGCAGTGATAAAAGGTCTGCAGAATAGCCAGCTAAGAAAAGGGTGTTTTGTTTCT
AGTGAACTAAATACAATAAATGAGGTGCCACGTTTTTAAATGACCCATTTTAATGAAATCTAGCTCATGCAGCTGCTTA
AATCAGATGAGTTAGGGTAGCAAAGCATGCTGCTCATTACACAGTAACACTTCTCCGCATAGGAGGTGTTTAGAAATGG
TGTAGTGAACCTAGAATGCCTACAGTAGTACCCGCTGAGGACCAGTTCTGGTGTTGACCAAAAGCTGAACCTGGAGGTA
CAGAAACCTCCACAAACGGCACACGGATTGGTCACTGAATTGTAAAATGAGATTATTTTTTTATTCTCAGTACGGCTTC
AACTTTCATCCCGAAGAATGTACAGAAGTGTTAAGAGTACACAACGTTTATTTTTTCACTTTCAACAGAGTTTTACAGA
CAGAATGTGTGTTGCATTGGGGCTCGCTGGTCCCAAGCTCTGTTACAGCAGCTGAAGTTCTTCGGTGACCCTCGGGTGA
GAGCGCTGCAGGCGCGACACGGCAGAGCCCCGCACCTAACAGATCTCCTAGCGCCTGACTGGGACACTGTGTTTGTTCG
TTCCAACAGACCGAAGGCTTTACATCAAATGTATGGCAAT
CitationMarx M, Lebuhotel C, Laugier D, Chapelle A, Calothy G, Saule S., Down regulation of pRb in cultures of avian neuroretina cells promotes proliferation of reactive Müller-like cells and emergence of retinal stem/progenitors. Exp Eye Res. 2010 Jun;90(6):791-801. Epub 2010 Apr 7.
CopyrightCopyright © 2012 Elsevier B.V. All rights reserved.
CommentsAs insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc #NM_204419.1 ).
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
25-30
stage 29
Retina
 
31-38
stage 35
stage 38
stage 38
Retina
 

Entry 3

GEISHA IdRB1.Trevers.2023Data SourceGEISHA ISH Analysis
Complete cDNA Template Probeshow
AATTTATATATTTTCGGGGGATTTTAAAAAGCAGCTTGGGAAGTGTCTTAGTTTGCTATTGCAGCGTTACTGATTGAAG
CCAGTTCAATCTACCTGGATTGAATATTTTCTGTCTCAAGACAAAACGTTAGCTAGGGATCTGAAGTGCACTAATTTTA
CTTCTTAGATTTCATTTTAATGTCGGATCTCAAAGCATTATTTGCAAGTATTGAAAATGAGGGGTCAGATGCCGCAAGG
ATTTCTGTCTCTGTGTGTAATTAACACATCCAATTCCCATTAACTTAGCTGCACAGCAGCCGTGCAGGGTCAGGGTCTC
CCCGCAGAAGCAGGAAGCAGTGAGCACGTCGTGTTAGCGGTACTACTGAAAGCAGTGAGCTGTGCTGCACCTCAGGTAC
GTCCCGTTCTGCAGTCCCCCAGCTCTCACCCCACACATTTCAGAGGGCCCACGTTGAATTTCATTGAATCTCACAGAGG
TTGAGTCCCACGAAGCAAAAAGGCGCATTCCCAAATGCAAAGTACCACGTTGTGCACTTTTGTATCTCGGAAAACCTCG
ATTTAAGAAAACACAAAGTAGAACACCCCCAACCTACATCACACCTCGCACACAGAAGATGGCAAAGGTCTCACAATGT
AGGATTCTCTTGAAGTGATTTCTACAGGTGTCCATGTGGCCGAACGTCACAGCACGGAGCTGTGTGCCTGAGGCGGTGC
CTTACCC
CommentsThe complete cDNA template sequence was obtained from the information from the publication as described in Trevers et al. 2023.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
X-XIV
stage XIII
Area Pellucida
Epiblast
 
1-3
stage 3
Epiblast
Primitive Streak
 
4-6
stage 6
Headfold
Primitive Streak
 
7-8
stage 8
Neural Plate/Tube
Primitive Streak
neural plate / primitive streak
all
 
  
 Data from NCBI Unigene EST Profile
Unigene ID: Gga.2986

Mouse

EmageMGI:97874
EurexpressMGI:97874
MGI GXDMGI:97874

Frog

Xenbase1018164

Fruit Fly

BDGP

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-040428-1
Home | Contact
     
© 2008 Arizona Board of Regents
This website is hosted by the Biotechnology Computing Facility at the University of Arizona