GEISHA - A Chicken Embryo Gene Expression Database
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HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase

Gene
Official SymbolHMGCR
Official Full Name3-hydroxy-3-methylglutaryl-CoA reductase
CGNC ID11100
also known asHMGR, 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
gene typeprotein-coding
Genomic Map
 Ensembl
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
RNANM_204485
PolypeptideNP_989816
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST ProfileGga.2785
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly42803FBgn0263782
Human3156ENSG00000113161MIM:142910MIM:142910
Mouse15357ENSMUSG00000021670All phenotypic alleles (4):Targeted, knock-out(1) Targeted, other(2) Gene trapped(1) MGI:96159
Xenopus100380121, 3977505840592
Zebrafish796384, 559054, 541479ENSDARG00000052734, ENSDARG00000059301ZDB-GENE-040401-2, ZDB-GENE-051108-1ZFIN:ZDB-GENE-040401-2, ZFIN:ZDB-GENE-051108-1
Gene Ontology
Molecular Function
Biological Process
Cellular Component
Links to other databases
Entrez Gene395145
Ensembl GeneENSGALG00000014948
KEGGgga:395145

Entry 1

GEISHA IdHMGCR.UApcrData SourceGEISHA ISH Analysis
Forward cDNA Template PrimerGCAACCCTGAGGAAACTTCGTC
Reverse cDNA Template PrimerATTAACCCTCACTAAAGGTACCAGCCATAGCAGAACCCACcDNA Template Length975
Forward cDNA Template Probeshow
CAGAATTGTTAATTCACTTCAACTATATCTTCCGGTAGTTGTCTTCAGTACTTCTTTAACAACCTTGGCTGGAATGACT
GCTTCACAGACAACAGACTTCCCTCTTCCCTCTATCCAATTGATAGCAGCAGGCTTTTTGTCTGTGCAGTAGTTACCGC
TGATAGCTATAACCTGGAGATCGGGAAACTCTTCATTCAGCCTTGCCAGTGCTTTTTCAGTACCTTTTGAAATCATATT
CATTCCCATTGCATCCCCTGTTTTGGACTGAAAACGAATGTAAAGGTTCCGACCAGCCAAGCTGATGAGAAGCTTTTGT
AGGCGGGCAAACCTACTTGTGCTGTCAAAAGCTTCTTTCACTATTTTAAAGCCTTCAGGGCTTTCAAGCCAAGCTTTCA
CTTCTGCAGCCTGGCAAGCAGAGGGCAGCCTTACAACAGGTCCTCGAGTCATCCCATCTGCAAGAATACGGCTCCTTGC
TCCTCCACCAAGACATATTGCTCTACATCCTCTATTTGTGCTTGCTACAAGACATCCTTCTGTTGTTGCCATTGGAACC
TGAAACTCTTTGTTATCCAGGTATAGTGGTCCTGCTACGCCTACAGGAATAGGCATATATCCAATCACGTTTTCACAGC
AAGCTCCTAAAACCAAAGAATAATTATAATTCCTGTAAGGAAGATACTGCAAAGATGAGGGTTCAGGGAGTTTCTGAGA
TAACATTTGTCTGCGAATAGACACTCCTCGCTCCTGAGTTTCCATCAGGGTTTCCAGTTTGTATGCAGGAATATGCTTT
GCATTAACTAAGCTGATCACTTCAGCATCAGTAAGGAATTTTGCTCCCTTCTCTGTACTTCCAAGTATACGAACACATT
CCTCAATAGAACGTGGTTCTTTAGGTAACTCAATTTCTTCCTCTTTTTTATTAANAACTGACGAAGTTCCCC
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
1-3
stage 3
Area Pellucida
Primitive Streak
 
4-6
stage 4
stage 5
Area Pellucida
Neural Plate/Tube
Primitive Streak
 
7-12
stage 7
stage 8
stage 9
stage 10
stage 12
Anterior Intestinal Portal
Area Opaca
Area Pellucida
Blood
Blood Islands
Extraembryonic Mesoderm
Head Mesenchyme
Headfold
Heart
Heart Tube
Intermediate Mesoderm
Lateral Plate Mesoderm
Neural Plate/Tube
Paraxial Mesoderm
Primitive Streak
Widespread Expression
 
13-18
stage 13
stage 17
Blood Islands
Head Mesenchyme
Heart
Intermediate Mesoderm
Lateral Plate Mesoderm
Neural Plate/Tube
Primitive Streak
Somites
Spinal Cord
Spinal Ganglia and Nerves
Widespread Expression
 
19-24
stage 20
Allantois
Eye
Forebrain
Hindbrain
Midbrain
Pharyngeal Arches and Clefts
Spinal Cord
Spinal Ganglia and Nerves
 
25
stage 25
Eye
Forebrain
Hindbrain
Midbrain
Pharyngeal Arches and Clefts
Spinal Cord
Spinal Ganglia and Nerves
 

Entry 2

GEISHA IdHMGCR.Olivera-Martinez.2014Data SourcePublication
Complete cDNA Template Probeshow
TGGCGGTGGCCGCCGCGTCGTGCCCCGGGTGTCCTTGTCCGGGGAGGAGCGGCCGCCTCAGTTCGCACCGCGGCGGGAG
GGAAGCAGGAAGCGGCAGGTTCTCGGCCGGGCGATTTGCTGACTGTAGAAAAACAGTTCTGAAAATGTTGTCCAGGCTT
TTTCGAATGCATGGCCTTTTTGTGGCCTCTCATCCATGGGAAGTCATTGTGGGAACAGTGACCCTTACCATCTGTATGA
TGTCAATGAAGATGTTCACTGGGAATGATAAGATCTGTGGCTGGAACTATGAGTGCCCAAAACTTGAAGAAGATGTTCT
GAGCAGTGACATCATAATCCTGACAATCACACGCTGTATAGCAATCCTTTATATATATTTCCAGTTTCAGAACCTAAGG
CAACTCGGATCAAAATACATTTTAGGTATTGCTGGTCTCTTCACAATCTTCTCAAGTTTTGTTTTTAGTACGGTGGTGA
TTCACTTCTTGGATAAAGAACTGACAGGTTTAAATGAAGCTTTACCGTTCTTCCTCCTTCTGATTGATCTTTCAAGAGC
AAGTGCTCTAGCCAAATTTGCACTAAGTTCCAATTCACAGGATGAAGTGAGAGAAAATATTTCACGTGGAATGGCAATT
TTAGGTCCTACATTTACCCTGGATGCACTTGTGGAATGTCTTGTGATTGGCGTTGGTACTATGTCAGGAGTGCGACAAC
TTGAAATCATGTGCTGCTTTGGCTGCATGTCTGTTCTCGCCAACTACTTTGTCTTCATGACCTTCTTTCCAGCTTGTGT
GTCCTTGGTATTAGAGCTTTCTCGAGAGAGTCGTGAAGGACGTCCTATATGGCAGCTGAGTCATTTCGCTCGTGTTCTG
GAAGAAGAAGAAAATAAACCAAACCCTGTAACACAGAGGGTCAAAATGATTATGTCACTGGGTTTGGTTCTTGTTCATG
CACACAGTCGCTGGATAGCGGAGCCAGCTTCTCAAAATGGTACAGTAGAAAATGCAGTGGGATTGGATGAGAATGCACC
AAAGAGAATTGAACCTAATGTTTCACTGTGGCAGTTCTACCTTTCTCGAATGGCCAGTATGGATATTGAACAAGTAATC
ACTCTTGGCTTAGCCTTTCTCCTTGCTGTGAAATACATTTTCTTTGAACAAGCAGAGACCGAATCCACGCTTTCATTGA
AGAATCCCATAACATCTCCTGTGACGGTCCAGAAAAAGGTCCCTGAGAATTGCTGCAGGAAACAATCTGGACTTTTGAA
AAATAGTCAGAAGACTAACACAGTAGAAGAAGCTTTTGTTGCTAAAGATGGAAATGCTGAAGTCATAAAGCCTGTGTTA
GCAGAGTCATCAACCAAAGCTACATTTGTAGTTGGCAGCTGCAACCCTGAGGAAACTTCGTCAGTTCTTAATAAAAAAG
AGGAAGAAATTGAGTTACCTAAAGAACCACGTTCTATTGAGGAATGTGTTCGTATACTTGGAAGTACAGAGAAGGGAGC
AAAATTCCTTACTGATGCTGAAGTGATCAGCTTAGTTAATGCAAAGCATATTCCTGCATACAAACTGGAAACCCTGATG
GAAACTCAGGAGCGAGGAGTGTCTATTCGCAGACAAATGTTATCTCAGAAACTCCCTGAACCCTCATCTTTGCAGTATC
TTCCTTACAGGAATTATAATTATTCTTTGGTTTTAGGAGCTTGCTGTGAAAACGTGATTGGATATATGCCTATTCCTGT
AGGCGTAGCAGGACCACTATACCTGGATAACAAAGAGTTTCAGGTTCCAATGGCAACAACAGAAGGATGTCTTGTAGCA
AGCACAAATAGAGGATGTAGAGCAATATGTCTTGGTGGAGGAGCAAGGAGCCGTATTCTTGCAGATGGGATGACTCGAG
GACCTGTTGTAAGGCTGCCCTCTGCTTGCCAGGCTGCAGAAGTGAAAGCTTGGCTTGAAAGCCCTGAAGGCTTTAAAAT
AGTGAAAGAAGCTTTTGACAGCACAAGTAGGTTTGCCCGCCTACAAAAGCTTCTCATCAGCTTGGCTGGTCGGAACCTT
TACATTCGTTTTCAGTCCAAAACAGGGGATGCAATGGGAATGAATATGATTTCAAAAGGTACTGAAAAAGCACTGGCAA
GGCTGAATGAAGAGTTTCCCGATCTCCAGGTTATAGCTATCAGCGGTAACTACTGCACAGACAAAAAGCCTGCTGCTAT
CAATTGGATAGAGGGAAGAGGGAAGTCTGTTGTCTGTGAAGCAGTCATTCCAGCCAAGGTTGTTAAAGAAGTACTGAAG
ACAACTACGGAAGATATAGTTGAAGTGAATATAAACAAAAATCTGGTGGGTTCTGCTATGGCTGGTAGCATAGGTGGCT
ACAACGCGCATGCTGCAAACATTGTTACAGCTATCTACATTGCCTGTGGTCAGGATGCTGCTCAGAATGTAGGCAGCTC
TAACTGCATCACTTTGATGGAGCGTACTGGTTCCACCAGTGAAGACCTCTATATCAGCTGCACAATGCCATCTATAGAG
ATAGGGACTGTTGGAGGAGGCACCAACTTGCTACCACAACAGGCCTGTTTGCAGATGTTGGGGGTTCAAGGTGCAAGCC
AAGACAACCCTGGTGAAAATGCCCGCCAGCTTGCTAAAATCGTGTGTGCTACAGTGATGGCTGGGGAGTTATCGCTAAT
GGCAGCTCTTGCAGCTGGGCATCTAGTCAAAAGCCACATGATCCACAACAGGTCAAAAATAAATCTACAAGATCTTCAA
GGAACCTGCACTAAGAAGGCAGCTTGAATACTACAGCTTTGAAATTAAGCAACTGACTTAGGAGTAAAGGGGAAAAAAA
TAATATAATCTGTGAAGCTTAGAATGAAAATCACCTTCAAGTCACTGATTTCTATGGACAGTAATCTGAGAGATAATGG
ACTTGTGTGAGACTACTTATGCCTTTTATGTTCTTCAATGATTAGAGATGACTTCATGAAAGAAGTGTTGTCAGCTGTC
TTAAATATAGTTTTGGAATTCTTACTCTTAAGCATCATTTTCTGAAAAGTCAGTCACGTGTTTTTACAGGTTGAGATTA
TTTTGACAAGTAAACTGGTAATTAGGAAGGTGAAATATGATGTGTACTCTGTACAGTTGTTTTTTGTTGTTGTTTTGTT
TCTTTCTTGAGGGGGAGGGGGATCGTTGATTGATTGTTTTTGTTTGTCTAACCTTGGCTTTAATGCATTGGTCCTTCTG
TAGTAATGGCGAACCTAATTGTTTTCCATGAATTCCCAGTTTTAATTTTGCTAAAATGTTGAAGTTAGGTCTTACGCTC
TGAGACAGTTTTTATCAGATCACATTAGCCCTACAGAAACCTGTCTACTTCTAGTACTTAATTTTCTGCAGCTAAGCAA
CATTCAGTGTGTATCTTCACAATTTAGATTATTACTTAAAGGAGAACTTGTGACCTACAAAGTGCTGAACTGTTAAATT
ATAGTATGTACTGAAGTAGGAAAAAAACAACAGTGTCTTAACTGTTCTGTCATTTAGTTCAGGTAC
CitationIsabel Olivera-Martinez, Nick Schurch, Roman A Li, Junfang Song, Pamela A Halley, Raman M Das, Dave W Burt, Geoffrey J Barton, Kate G Storey. Major transcriptome re-organisation and abrupt changes in signalling, cell cycle and chromatin regulation at neural differentiation in vivo. Development 2014 Aug;141(16):3266-76. Epub 2014 Jul 25. DOI: 10.1242/dev.112623.
CopyrightCopyright © 2014. Published by The Company of Biologists Ltd.
CommentsAs insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence above was obtained from NCBI (accession number NM_204485.2).
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
7-10
stage 10
Neural Plate/Tube
Somites
 
all
 
  
 Data from NCBI Unigene EST Profile
Unigene ID: Gga.2785

Mouse

EmageMGI:96159
EurexpressMGI:96159
MGI GXDMGI:96159

Frog

Xenbase5840592

Fruit Fly

BDGPFBgn0263782

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-040401-2, ZDB-GENE-051108-1
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