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 | IL6
interleukin 6 | The human orthologue of this gene is associated
with the following human diseases: |
| Gene | | Official Symbol | IL6 | | Official Full Name | interleukin 6 | | CGNC ID | 8294 | | also known as | CHIL-6, IL-6, interleukin-6, interleukin-6|interleukin 6 (interferon, beta 2) | | gene type | protein-coding |
| | Genomic Map | | | Sequence Information | | | Gene Expression | | | Orthology | | | Gene Ontology | | Molecular Function | cytokine activity, growth factor activity, interleukin-6 receptor binding | | Biological Process | acute-phase response, branching involved in salivary gland morphogenesis, more...cellular response to hydrogen peroxide, defense response to Gram-negative bacterium, defense response to Gram-positive bacterium, defense response to protozoan, defense response to virus, endocrine pancreas development, epithelial cell proliferation involved in salivary gland morphogenesis, glucagon secretion, immune response, interleukin-6-mediated signaling pathway, muscle cell cellular homeostasis, negative regulation of apoptotic process, negative regulation of chemokine biosynthetic process, negative regulation of collagen biosynthetic process, negative regulation of hormone secretion, neuron projection development, neutrophil apoptotic process, positive regulation of acute inflammatory response, positive regulation of apoptotic process, positive regulation of B cell activation, positive regulation of chemokine production, positive regulation of epithelial cell proliferation, positive regulation of immunoglobulin secretion, positive regulation of interleukin-6 production, positive regulation of JAK-STAT cascade, positive regulation of MAPK cascade, positive regulation of peptidyl-serine phosphorylation, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of smooth muscle cell proliferation, positive regulation of T cell proliferation, positive regulation of T-helper 2 cell differentiation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of translation, regulation of vascular endothelial growth factor production, response to glucocorticoid, response to peptidoglycan, T cell activation | | Cellular Component | external side of plasma membrane, extracellular space, interleukin-6 receptor complex |
| | Links to other databases | |
No expression data available.
| | Data from NCBI Unigene EST Profile
Unigene ID: Gga.2769 |
MouseFrogFruit FlyZebra FinchZebrafish |
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