Geisha

home

contact

A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

Quick Search

Data Class

Enter Text:

Gene Family QuickSearch

	Transcription Factors
	Growth Factors
	Receptors
	MicroRNAs

Human Disease Gene Search

	Downloads
	Protocols
	About GEISHA
	Contact Us

	Transgenic Birds
	Model Organism Databases
	Gene Expression Databases
	Genomic Resources
	Anatomical Atlases
	Chicken Stage Series

GSN
gelsolin

The human orthologue of this gene is associated
with the following human disease:

Amyloidosis, Finnish type

Gene

Official Symbol	GSN
Official Full Name	gelsolin
CGNC ID	49472
also known as	gelsolin\|ADF\|actin-depolymerizing factor\|brevin\|homogenin
gene type	protein-coding

Genomic Map

	Ensembl
	NCBI
	UCSC
	Gallus-Browse

Sequence Information

Genomic
RNA	NM_204934
Polypeptide	NP_990265
Sequence Clusters/ESTs	Unigene

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.4451

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly
Human	2934	ENSG00000148180	MIM:105120	MIM:137350
Mouse	227753	ENSMUSG00000026879	All phenotypic alleles (4):Targeted, knock-out(2) Targeted, other(2)	MGI:95851
Xenopus	549610, 397895			489534
Zebrafish	321099, 336623	ENSDARG00000011459, ENSDARG00000045262	ZDB-GENE-030131-9653, ZDB-GENE-030131-8567	ZFIN:ZDB-GENE-030131-9653, ZFIN:ZDB-GENE-030131-8567

Gene Ontology

Molecular Function	actin binding, metal ion binding
Biological Process	actin filament capping, cilium morphogenesis
Cellular Component	cytoplasm, cytoskeleton, extracellular region

Links to other databases

Entrez Gene	395774
Ensembl Gene	ENSGALG00000001446
KEGG	gga:395774

Entry 1

GEISHA Id	GSN.UApcr	Data Source	GEISHA ISH Analysis
Forward cDNA Template Primer	5’-AGACCACACCAGCACAAACA-3’
Reverse cDNA Template Primer	5’-AATTAACCCTCACTAAAGGAGAAGGTTGGAGGCTCAAGC-3’	cDNA Template Length	600
Complete cDNA Template Probe	show AGACCACACCAGCACAAACACGCCTGTTCCAGGTCCGGTCCAGCACCTCGGGAGCCACCAGAGCTGTAGAGCTGGATCC TGCTGCAAGTCAGCTGAACTCCAATGATGCTTTTGTCCTGAAAACTCCCTCTGCTGCTTACCTCTGGGTTGGCCGAGGC TCCAACAGTGCCGAGCTGTCAGGAGCACAAGAACTGCTGAAGGTTCTGGGAGCTCGCCCAGTACAGGTTTCCGAGGGTA GAGAGCCAGATAACTTTTGGGTGGCTTTGGGTGGAAAAGCTCCCTACCGTACCTCTCCTCGGCTGAAGGACAAGAAGAT GGATGCTTACCCCCCTCGTCTTTTTGCATGCTCCAACAAGAGTGGACGCTTCACTATTGAAGAAGTCCCTGGAGATCTG ACTCAGGATGACCTTGCAACAGATGATGTTATGATCCTTGACACATGGGATCAGGTGTTTGTATGGATTGGAAAAGATG CCCAGGAGGAAGAAAAGACTGAGGCTTTGAAATCAGCTAAACGATACATTGAAACTGATCCAGCCAGCCGTGATAAGAG AACTCCAGTCACACTGGTTAAGCAGGGGCTTGAGCCTCCAACCTTCT

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

4-6

stage 4

stage 5

Primitive Streak

7-12

stage 8

stage 9

stage 11

Amnion
Anterior Intestinal Portal
Area Opaca
Blood Islands
Forebrain
Head Mesenchyme
Hindbrain
Lateral Plate Mesoderm
Midbrain
Neural Plate/Tube
Primitive Streak
Sinus Venosus
Somites
Ventricles
extraembryonic ectoderm
extraembryonic endoderm
extraembryonic mesoderm

13-18

stage 16

Foregut
Head Mesenchyme
Heart
Myotome
Neural Plate/Tube
Sclerotome
Yolk Sack or Stalk

19-24

stage 19

stage 24

Allantois
Ear/Otic Placode
Eye
Foregut
Head Mesenchyme
Heart
Isthmus/MHB
Leg Mesenchyme
Liver
Lung
Mesonephros
Midbrain
Neural Plate/Tube
Oral Pharynx
Pharyngeal Arches and Clefts
Sclerotome
Sinus Venosus
Spinal Ganglia and Nerves
Ventricles
Widespread Expression
Wing Mesenchyme

25-26

stage 26

Allantois
Foregut
Head Mesenchyme
Heart
Leg Mesenchyme
Mesonephros
Myotome
Pharyngeal Arches and Clefts
Sclerotome
Spinal Cord
Spinal Ganglia and Nerves
Ventricles
Wing Mesenchyme

Entry 2

GEISHA Id	HOMOGENIN.Heller.1998	Data Source	Publication
Complete cDNA Template Probe	show AAAAGAGATCGAATTCGGCACGAGGGAGCTGAGACTCCCTGCAGCTACTGCAGGAGGAGGGAGAAGCCCATTTGCTGTT AGAAATGGGAAAGCAGGGCTTTGGTTATATTTTTCTTACCATTTTTTGCACAATGGCTCTGAAGCTGAACTGTGTGAGC TCCGTGTCTGTTGCAGGGCTTGGCTATGTTGTTACAGCAGCTGTGGTGCTTTCAGCTGTGCCTGTCAGCATGGTGGAGC ACGCTGAGTTTTCGAAGGCTGGGAAGGAGCCTGGCCTCCAGATTTGGAGGATCGAGAAATTTGATTTGGTACCAGTGCC AAAAAATCTGTACGGAGACTTCTTCACAGGGGATTCCTATCTGGTGCTGAACACCATCAGGCAGCGGAGTGGGAACCTC CAGTACGACTTGCACTTCTGGTTAGGAGATGAAAGCTCTCAAGATGAGCGTGGGGCAGCTGCCATATTCACTGTTCAGA TGGATGACTACCTGCAAGGGAAAGCTGTCCAGCACCGTGAAGTGCAAGGCCATGAATCCTCAACGTTCCTGGGGTATTT CAAGTCTGGCATCAAGTACAAGGCTGGTGGCGTGGCTTCTGGCTTCAGGCATGTGGTTCCCAATGAAGTAACTGTGCAG AGGCTTCTCCAGGTCAAGGGCAGGAGAACAGTCAGAGCAACAGAGGTCCCTGTGAGCTGGGAGAGCTTCAACACGGGGG ATTGTTTCATCCTTGACCTTGGCAGTAACATCTATCAGTGGTGTGGCTCCAACAGCAACCGCCAGGAGCGTCTGAAGGC CACTGTCCTAGCCAAGGGGATTCGGGACAATGAGAAGAACGGTCGTGCCAAAGTCTTTGTTTCAGAGGAAGGAGCAGAA CGGGAGGAAATGCTTCAGGTCCTAGGACCAAAGCCCAGCTTGCCACAAGGAGCTTCTGATGATACTAAAACTGATACAG CCAATAGAAAGCTGGCTAAGCTCTATAAGGTCTCAAATGGGGCTGGGAACATGGCAGTTTCCCTTGTGGCAGATGAAAA CCCCTTCTCCCAGGCAGCACTGAACACGGAAGACTGCTTCATTCTGGACCATGGCACAGATGGAAAGATCTTTGTTTGG AAAGGCAGGAGTGCCAATTCTGATGAGAGAAAGGCAGCCCTGAAAACAGCTACTGATTTCATTGATAAGATGGGTTATC CGAAACATACCCAGGTCCAAGTTCTCCCTGAGAGTGGTGAAACACCTTTGTTTAAACAATTCTTCAAGAACTGGAGGGA CAAGGACCAGACAGAAGGACTGGGAGAGGCTTACATTTCTGGTCATGTTGCCAAAATCGAGAAAGTACCTTTTGATGCT GCCACTCTACACACCTCCAGGGCCATGGCTGCCCAGCATGGCATGGAGGATGATGGTTCTGGCAAGAAACAGATTTGGA GAATAGAAGGGTCAGAGAAAGTGCCAGTGGATCCTGCAACATATGGCCAATTCTATGGAGGGGATAGTTATATCATCTT GTATGACTACCGGCATGCTGGAAAGCAGGGGCAGATCATTTACACTTGGCAGGGTGCTCATTCCACTCAAGATGAAATT GCGACTTCGGCATTCCTCACAGTACAGCTGGATGAGGAGCTGGGAGGCAGCCCTGTGCAGAAACGAGTAGTGCAAGGAA AAGAGCCACCTCATCTGATGAGCATGTTTGGAGGAAAACCCTTGATTGTTTACAAGGGTGGAACATCTCGGGAAGGAGG CCAGACCACACCAGCACAAACACGCCTGTTCCAGGTCCGGTCCAGCACCTCGGGAGCCACCAGAGCTGTAGAGCTGGAT CCTGCTGCAAGTCAGCTGAACTCCAATGATGCTTTTGTCCTGAAAACTCCCTCTGCTGCTTACCTCTGGGTTGGCCGAG GCTCCAACAGTGCCGAGCTGTCAGGAGCACAAGAACTGCTGAAGGTTCTGGGAGCTCGCCCAGTACAGGTTTCCGAGGG TAGAGAGCCAGATAACTTTTGGGTGGCTTTGGGTGGAAAAGCTCCCTACCGTACCTCTCCTCGGCTGAAGGACAAGAAG ATGGATGCTTACCCCCCTCGTCTTTTTGCATGCTCCAACAAGAGTGGACGCTTCACTATTGAAGAAGTCCCTGGAGATC TGACTCAGGATGACCTTGCAACAGATGATGTTATGATCCTTGACACATGGGATCAGGTGTTTGTATGGATTGGAAAAGA TGCCCAGGAGGAAGAAAAGACTGAGGCTTTGAAATCAGCTAAACGATACATTGAAACTGATCCAGCCAGCCGTGATAAG AGAACTCCAGTCACACTGGTTAAGCAGGGGCTTGAGCCTCCAACCTTCTCTGGCTGGTTCCTGGGCTGGGATGATGACT ACTGGTCTGTTGATCCTCTGCAGAGAGCAATGGCAGATGTGGATGTCTAAGTAACAGGTTTTTCCTCTTTTTAATAGAG CAAGTTTAGTTCCTTCAGTGCCTTCAAGAGCTGCTTCCTCCTGCTGGATGGATGCTAGCATGGCAATGATGTTAATAGC CAATTAGCTGTGCAATAAGTACCAAAACCAATCACGACCAGTCATACTGCTCTATTCCTTGCTTTGATTATATTTAATA TGGTAAAGCTTGTTTGGAATAGGAGAAGAATGGGTAAGCTTTGTTACTAAGATGAAAACATTAAACAGAATCTGTAGAT CCCACATTTGAACTTACTTGAAACA
Citation	Heller S, Sheane CA, Javed Z, Hudspeth AJ. Molecular markers for cell types of the inner ear and candidate genes for hearing disorders. Proc Natl Acad Sci U S A. 1998 Sep 15;95(19):11400-5.
Copyright	Copyright © 2012 National Academy of Sciences. All rights reserved.
Comments	As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # NM_204934).