GEISHA - A Chicken Embryo Gene Expression Database
Browse By
- Anatomical Location
- Stage
- Gene Name
- GEISHA ID
- Multiple Parameters
Search
- Quick Search
Data Class
Enter Text:
go
- Gene Family QuickSearch
Transcription Factors
Growth Factors
Receptors
MicroRNAs
- Human Disease Gene Search
Documents
- Downloads
- Protocols
- About GEISHA
- Contact Us
Resources
- Transgenic Birds
- Model Organism Databases
- Gene Expression Databases
- Genomic Resources
- Anatomical Atlases
- Chicken Stage Series
_

AXIN1
axin 1

The human orthologue of this gene is associated
with the following human diseases:
Gene
Official SymbolAXIN1
Official Full Nameaxin 1
CGNC ID49477
also known asAXIN, AXIN1-RGS, axin-1, axin-1|axis inhibition protein 1
gene typeprotein-coding
Genomic Map
 Ensembl ID not known
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
RNANM_204944
PolypeptideNP_990275
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST ProfileGga.464
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly
Human8312ENSG00000103126MIM:607864MIM:603816
Mouse12005ENSMUSG00000024182All phenotypic alleles (15):Spontaneous(3) Targeted, knock-out(1) Targeted, other(10) Transgenic(1) MGI:1096327
Xenopus100498631, 734298486780
Zebrafish57931ENSDARG00000026534ZDB-GENE-000403-1ZFIN:ZDB-GENE-000403-1
Gene Ontology
Molecular Functionarmadillo repeat domain binding, beta-catenin binding, GTPase activator activity, more...protein homodimerization activity, protein kinase binding, signal transducer activity
Biological Processactivation of JUN kinase activity, axial mesoderm formation, more...canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation, cell death, cellular response to organic cyclic compound, cytoplasmic microtubule organization, determination of left/right symmetry, dorsal/ventral axis specification, embryonic eye morphogenesis, embryonic skeletal joint morphogenesis, forebrain anterior/posterior pattern specification, muscle cell development, negative regulation of canonical Wnt signaling pathway, negative regulation of fat cell differentiation, olfactory placode formation, optic placode formation, positive regulation of GTPase activity, positive regulation of JNK cascade, regulation of catenin import into nucleus, termination of G-protein coupled receptor signaling pathway, Wnt-activated signaling pathway involved in forebrain neuron fate commitment, Wnt signaling pathway involved in somitogenesis
Cellular Componentcell cortex, cytoplasm, cytoplasmic membrane-bounded vesicle, cytoplasmic microtubule, plasma membrane, more...postsynaptic density
Links to other databases
Entrez Gene395786
Ensembl Gene
KEGGgga:395786

Entry 1

GEISHA IdAXIN1.UApcrData SourceGEISHA ISH Analysis
Forward cDNA Template Primer5’-TCCGACTTGGATCTGGGCTA-3’
Reverse cDNA Template Primer5’-AATTAACCCTCACTAAAGGTGTGAGCGACATCGTATCCG-3’cDNA Template Length819
Complete cDNA Template Probeshow
TCCGACTTGGATCTGGGCTACGAACCCGAGGGGAGCGCTTCGCCAACTCCACCCTACCTGAAGTGGGCCGAGTCGCTGC
ACTCCTTGCTGGACGATCAAGACGGTATCAATCTCTTCAGGACTTTCCTGAAACAGGAGGACTGTGCGGATCTGCTGGA
CTTCTGGTTTGCCTGCAGCGGCTTCAGGAAGCTGGAGCCGTGTGTGTCCAATGAGGAAAAAAGACTCAAACTGGCAAAA
GCCATTTACAAAAAGTACATTCTCGACAACAACGGCATTGTGTCCCGGCAGATCAAACCAGCCACAAAAAGCTTCATAA
AAGACTGTGTCATGAAACTGCAGATTGACCCTGACATGTTTGACCAGGCCCAAACTGAGATTCAGTGCATGATAGAAGA
CAATACCTACCCTTTGTTCCTTAAGTCGGATATTTATTTGGAATACACAAGGACAGGTGGGGAAAGTCCAAAAATTTAT
AGCGATCCGAGCTCAGGGTCTGGGACAGGTAAAGGGCTACCTGGTTATCTGCCTACTCTGAATGAGGACGAGGAGTGGA
AATGTGACCAAGACACCGAGCCTGAGGCCAGCAGGGACTCCGCGCCCTCAAGCAGGCTCACCCAGAAGCTGCTTTTGGA
GACTGCAACCCAGCGTGCCACCTCGACCCGGCGGTACAGCGAGGGCAGGGAGTTCAGGCATGGGTCATGGAGAGAACCT
GTTAACCCTTACTATGTCAACACGGGATATGCCATGGCACCAGCCACCAGTGCCAACGACAGCGAGCAGCAGAGCATGT
CCAGTGATGCGGATACGATGTCGCTCACA
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
4-6
stage 5
Unlabeled
 
7-12
stage 8
stage 9
stage 11
Forebrain
Hindbrain
Midbrain
Neural Plate/Tube
 
13-18
stage 18
Widespread Expression
 
19-24
stage 22
Forebrain
Foregut
Head Mesenchyme
Hindbrain
Leg Mesenchyme
Lung
Midbrain
Neural Plate/Tube
Outflow Tract
Pharyngeal Arches and Clefts
Sclerotome
Wing Mesenchyme
 
25-26
stage 26
stage 26
stage 26
Forebrain
Foregut
Head Mesenchyme
Hindbrain
Leg Mesenchyme
Midbrain
Myotome
Pharyngeal Arches and Clefts
Sclerotome
Spinal Cord
Wing Mesenchyme
 

Entry 2

GEISHA IdAXIN1.Quinlan.2009Data SourcePublication
Complete cDNA Template Probeshow
TCACCACATCCATCACCACAGCATGATGAAACCAAAAGAGCAAATTGAGGCCGAGGCCACGCAGAGGGTGCAGAACAGC
TTTGCTTGGAATGTAGATTCACATAACTATGCAACAAAGTCAAGAAACTACTCTGAAAACTTGGGCATGGCCCCTGTCC
CCATGGACTCTTTAGGCTACAGTGGGAAAGCAAGTCTGCTCTCAAAAAGAAATATTAAGAAGACCGATTCAGGGAAAAG
TGATGGTGCCAACTATGAGATGCCAGGATCTCCTGAAGACGTGGAGAGAAACCAGAAGATCCTTCAGTGGATCATAGAA
GGAGAGAAGGAGATCAGCAGGCATAAGAAAACAAACCATGGCTCTTCAGGTGCTAAGAAGCAGCTGTCCCATGACGTGG
TCCGACCCCTCTCCATCGAGCGGCCTGTTGCAGTGCATCCGTGGGTCAGTGCCCAGCTTCGGAACGTCGTCCAGCCTTC
ACACCCTTTCATCCAAGATCCTACCATGCCACCCAACCCAGCGCCCAACCCACTCACCCAGCTGGAAGAAGCTCGCAGG
AGGTTGGAGGAGGAGGAAAAGAGAGCTGGAAAACTCCCACTGAAACAAAGGTTGAAGCCCCAGAAGAGACCGGGCAGTG
GTGCTTCCCAGCCGTGTGAGAACATCGTGGTTGCTTACTACTTCTGTGGAGAGCCCATCCCGTACCGTACCCTCGTCAA
AGGGCGCGTGGTGACACTGGGACAGTTCAAGGAGCTGCTGACCAAGAAAGGGAACTACAGGTATTACTTTAAGAAAGTG
AGTGATGAGTTCGACTGCGGTGTGGTCTTTGAGGAGGTGCGGGAGGAACGACACCA
CitationQuinlan R, Graf M, Mason I, Lumsden A, Kiecker C. Complex and dynamic patterns of Wnt pathway gene expression in the developing chick forebrain. Neural Dev. 2009 Sep 4;4:35.
CopyrightCopyright © 2009 Quinlan et al; licensee BioMed Central Ltd. [This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.]
CommentsAuthors said probe came from ChEST175L2; the sequence below was obtained from NCBI (acc # BU409223.1).
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
13-18
stage 13
Diencephalon
Isthmus/MHB
Midbrain
Shh in red, double label
19-20
stage 20
Diencephalon
Isthmus/MHB
Midbrain
Shh in red, double label
 Data from NCBI Unigene EST Profile
Unigene ID: Gga.464

Mouse

EmageMGI:1096327
EurexpressMGI:1096327
MGI GXDMGI:1096327

Frog

Xenbase486780

Fruit Fly

BDGP

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-000403-1
Home | Contact
     
© 2008 Arizona Board of Regents
This website is hosted by the Biotechnology Computing Facility at the University of Arizona