| |
 | AXIN1
axin 1 | The human orthologue of this gene is associated
with the following human diseases: |
| Gene | | Official Symbol | AXIN1 | | Official Full Name | axin 1 | | CGNC ID | 49477 | | also known as | AXIN, AXIN1-RGS, axin-1, axin-1|axis inhibition protein 1 | | gene type | protein-coding |
| | Genomic Map | | | Sequence Information | | | Gene Expression | | | Orthology | | | Gene Ontology | | Molecular Function | armadillo repeat domain binding, beta-catenin binding, GTPase activator activity, more...protein homodimerization activity, protein kinase binding, signal transducer activity | | Biological Process | activation of JUN kinase activity, axial mesoderm formation, more...canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation, cell death, cellular response to organic cyclic compound, cytoplasmic microtubule organization, determination of left/right symmetry, dorsal/ventral axis specification, embryonic eye morphogenesis, embryonic skeletal joint morphogenesis, forebrain anterior/posterior pattern specification, muscle cell development, negative regulation of canonical Wnt signaling pathway, negative regulation of fat cell differentiation, olfactory placode formation, optic placode formation, positive regulation of GTPase activity, positive regulation of JNK cascade, regulation of catenin import into nucleus, termination of G-protein coupled receptor signaling pathway, Wnt-activated signaling pathway involved in forebrain neuron fate commitment, Wnt signaling pathway involved in somitogenesis | | Cellular Component | cell cortex, cytoplasm, cytoplasmic membrane-bounded vesicle, cytoplasmic microtubule, plasma membrane, more...postsynaptic density |
| | Links to other databases | |
Entry 1| GEISHA Id | AXIN1.UApcr | Data Source | GEISHA ISH Analysis | | Forward cDNA Template Primer | 5’-TCCGACTTGGATCTGGGCTA-3’ | | Reverse cDNA Template Primer | 5’-AATTAACCCTCACTAAAGGTGTGAGCGACATCGTATCCG-3’ | cDNA Template Length | 819 | | Complete cDNA Template Probe | show TCCGACTTGGATCTGGGCTACGAACCCGAGGGGAGCGCTTCGCCAACTCCACCCTACCTGAAGTGGGCCGAGTCGCTGC
ACTCCTTGCTGGACGATCAAGACGGTATCAATCTCTTCAGGACTTTCCTGAAACAGGAGGACTGTGCGGATCTGCTGGA
CTTCTGGTTTGCCTGCAGCGGCTTCAGGAAGCTGGAGCCGTGTGTGTCCAATGAGGAAAAAAGACTCAAACTGGCAAAA
GCCATTTACAAAAAGTACATTCTCGACAACAACGGCATTGTGTCCCGGCAGATCAAACCAGCCACAAAAAGCTTCATAA
AAGACTGTGTCATGAAACTGCAGATTGACCCTGACATGTTTGACCAGGCCCAAACTGAGATTCAGTGCATGATAGAAGA
CAATACCTACCCTTTGTTCCTTAAGTCGGATATTTATTTGGAATACACAAGGACAGGTGGGGAAAGTCCAAAAATTTAT
AGCGATCCGAGCTCAGGGTCTGGGACAGGTAAAGGGCTACCTGGTTATCTGCCTACTCTGAATGAGGACGAGGAGTGGA
AATGTGACCAAGACACCGAGCCTGAGGCCAGCAGGGACTCCGCGCCCTCAAGCAGGCTCACCCAGAAGCTGCTTTTGGA
GACTGCAACCCAGCGTGCCACCTCGACCCGGCGGTACAGCGAGGGCAGGGAGTTCAGGCATGGGTCATGGAGAGAACCT
GTTAACCCTTACTATGTCAACACGGGATATGCCATGGCACCAGCCACCAGTGCCAACGACAGCGAGCAGCAGAGCATGT
CCAGTGATGCGGATACGATGTCGCTCACA |
Entry 2| GEISHA Id | AXIN1.Quinlan.2009 | Data Source | Publication | | Complete cDNA Template Probe | show TCACCACATCCATCACCACAGCATGATGAAACCAAAAGAGCAAATTGAGGCCGAGGCCACGCAGAGGGTGCAGAACAGC
TTTGCTTGGAATGTAGATTCACATAACTATGCAACAAAGTCAAGAAACTACTCTGAAAACTTGGGCATGGCCCCTGTCC
CCATGGACTCTTTAGGCTACAGTGGGAAAGCAAGTCTGCTCTCAAAAAGAAATATTAAGAAGACCGATTCAGGGAAAAG
TGATGGTGCCAACTATGAGATGCCAGGATCTCCTGAAGACGTGGAGAGAAACCAGAAGATCCTTCAGTGGATCATAGAA
GGAGAGAAGGAGATCAGCAGGCATAAGAAAACAAACCATGGCTCTTCAGGTGCTAAGAAGCAGCTGTCCCATGACGTGG
TCCGACCCCTCTCCATCGAGCGGCCTGTTGCAGTGCATCCGTGGGTCAGTGCCCAGCTTCGGAACGTCGTCCAGCCTTC
ACACCCTTTCATCCAAGATCCTACCATGCCACCCAACCCAGCGCCCAACCCACTCACCCAGCTGGAAGAAGCTCGCAGG
AGGTTGGAGGAGGAGGAAAAGAGAGCTGGAAAACTCCCACTGAAACAAAGGTTGAAGCCCCAGAAGAGACCGGGCAGTG
GTGCTTCCCAGCCGTGTGAGAACATCGTGGTTGCTTACTACTTCTGTGGAGAGCCCATCCCGTACCGTACCCTCGTCAA
AGGGCGCGTGGTGACACTGGGACAGTTCAAGGAGCTGCTGACCAAGAAAGGGAACTACAGGTATTACTTTAAGAAAGTG
AGTGATGAGTTCGACTGCGGTGTGGTCTTTGAGGAGGTGCGGGAGGAACGACACCA | | Citation | Quinlan R, Graf M, Mason I, Lumsden A, Kiecker C. Complex and dynamic patterns of Wnt pathway gene expression in the developing chick forebrain. Neural Dev. 2009 Sep 4;4:35. | | Copyright | Copyright © 2009 Quinlan et al; licensee BioMed Central Ltd. [This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.] | | Comments | Authors said probe came from ChEST175L2; the sequence below was obtained from NCBI (acc # BU409223.1). |
| | Data from NCBI Unigene EST Profile
Unigene ID: Gga.464 |
MouseFrogFruit FlyZebra FinchZebrafish |
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