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| SLC11A1 solute carrier family 11 member 1 | The human orthologue of this gene is associated with the following human diseases: |
Gene | Official Symbol | SLC11A1 | Official Full Name | solute carrier family 11 member 1 | CGNC ID | 8689 | also known as | BCG, NRAMP1, natural resistance-associated macrophage protein 1|NRAMP 1|natural resistant-associated macrophage protein 1|solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1|solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 | gene type | protein-coding |
| Genomic Map | | Sequence Information | | Gene Expression | | Orthology | | Gene Ontology | Molecular Function | manganese ion transmembrane transporter activity, metal ion:hydrogen antiporter activity, more...protein homodimerization activity, transition metal ion transmembrane transporter activity | Biological Process | activation of protein kinase activity, antigen processing and presentation of peptide antigen, more...cadmium ion transmembrane transport, cellular cadmium ion homeostasis, cellular iron ion homeostasis, defense response to Gram-negative bacterium, defense response to protozoan, divalent metal ion export, inflammatory response, interleukin-2 production, interleukin-3 production, iron ion transport, L-arginine import, macrophage activation, MHC class II biosynthetic process, mRNA stabilization, multicellular organismal iron ion homeostasis, negative regulation of cytokine production, nitrite transport, phagocytosis, positive regulation of dendritic cell antigen processing and presentation, positive regulation of interferon-gamma production, positive regulation of phagocytosis, positive regulation of T-helper 1 type immune response, positive regulation of transcription from RNA polymerase II promoter, protein import into nucleus, translocation, respiratory burst, response to interferon-gamma, T cell cytokine production, T cell proliferation involved in immune response, vacuolar acidification, wound healing | Cellular Component | cell outer membrane, endosome membrane, integral component of membrane, late endosome, lysosome, more...phagocytic vesicle membrane, plasma membrane, tertiary granule membrane |
| Links to other databases | |
No expression data available.
| Data from NCBI Unigene EST Profile Unigene ID: Gga.477 |
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