GEISHA - A Chicken Embryo Gene Expression Database
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PTPN11
protein tyrosine phosphatase, non-receptor type 11

The human orthologue of this gene is associated
with the following human diseases:
Gene
Official SymbolPTPN11
Official Full Nameprotein tyrosine phosphatase, non-receptor type 11
CGNC ID
also known asSYP, tyrosine-protein phosphatase non-receptor type 11|SH-PTP2|cSH-PTP2
gene typeprotein-coding
Genomic Map
 Ensembl
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
RNANM_204968
PolypeptideNP_990299
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST ProfileGga.482
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly45278FBgn0000382
Human5781ENSG00000179295MIM:151100MIM:176876
Mouse19247ENSMUSG00000043733All phenotypic alleles (19):Targeted, knock-out(4) Targeted, other(15) MGI:99511
Xenopus548434, 444193, 3992916054494
Zebrafish100330785, 333979, 393426ENSDARG00000020334, ENSDARG00000012340ZDB-GENE-030131-5911, ZDB-GENE-040426-1158ZFIN:ZDB-GENE-030131-5911, ZFIN:ZDB-GENE-040426-1158
Gene Ontology
Molecular Functioninsulin receptor binding, non-membrane spanning protein tyrosine phosphatase activity, more...peptide hormone receptor binding, receptor tyrosine kinase binding, SH3/SH2 adaptor activity
Biological Processactivation of MAPK activity, atrioventricular canal development, axonogenesis, brain development, more...DNA damage checkpoint, ephrin receptor signaling pathway, ERBB signaling pathway, face morphogenesis, genitalia development, glucose homeostasis, hormone-mediated signaling pathway, hormone metabolic process, inner ear development, multicellular organismal reproductive process, negative regulation of cortisol secretion, negative regulation of growth hormone secretion, negative regulation of insulin secretion, neurotrophin TRK receptor signaling pathway, organ growth, positive regulation of glucose import in response to insulin stimulus, positive regulation of hormone secretion, regulation of cell adhesion mediated by integrin, regulation of multicellular organism growth, regulation of protein export from nucleus, triglyceride metabolic process
Cellular Componentcytoplasm, nucleus
Links to other databases
Entrez Gene395815
Ensembl GeneENSGALG00000004821
KEGGgga:395815
No expression data available.
 Data from NCBI Unigene EST Profile
Unigene ID: Gga.482

Mouse

Emage
EurexpressMGI:99511
MGI GXDMGI:99511

Frog

Xenbase6054494

Fruit Fly

BDGPFBgn0000382

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-030131-5911, ZDB-GENE-040426-1158
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