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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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GJA8
gap junction protein alpha 8

The human orthologue of this gene is associated
with the following human diseases:

Gene

Official Symbol	GJA8
Official Full Name	gap junction protein alpha 8
CGNC ID	11546
also known as	Cx45.6, Cx50, connexin-45.6, gap junction alpha-8 protein\|connexin 45.6\|connexin 50
gene type	protein-coding

Genomic Map

	Ensembl
	NCBI
	UCSC

Sequence Information

Genomic
RNA	NM_204997
Polypeptide	NP_990328

Gene Expression

In Situ Hybridization

GEISHA

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly
Human	2703		MIM:600897	MIM:600897
Mouse	14616		All phenotypic alleles (10):Spontaneous(1) Chemically induced(3) Targeted, knock-out(2) Targeted, other(4)	MGI:99953
Xenopus	100490617, 100381091			493229
Zebrafish	114403	ENSDARG00000015076	ZDB-GENE-050616-14, ZDB-GENE-010607-3	ZFIN:ZDB-GENE-050616-14, ZFIN:ZDB-GENE-010607-3

Gene Ontology

Molecular Function	protein binding
Biological Process	cell communication
Cellular Component	connexon complex, integral component of membrane

Links to other databases

Entrez Gene	395846
Ensembl Gene	ENSGALG00000015488
KEGG	gga:395846

Entry 1

GEISHA Id	GJA8.UApcr	Data Source	GEISHA ISH Analysis
Forward cDNA Template Primer	5’-TATGGCTTCCGCATTCTCCC-3’
Reverse cDNA Template Primer	5’-AATTAACCCTCACTAAAGGTCACATCGGTGGCAAGTTCA-3’	cDNA Template Length	619
Complete cDNA Template Probe	show TATGGCTTCCGCATTCTCCCCCTTTACCGCTGTGGGCGGTGGCCCTGTCCCAACCTAGTGGACTGTTTTGTCTCCAGGC CCACAGAGAAGACCATCTTTATTATGTTCATGCTCGTGGTGGCTGCTGTGTCCCTCTTCCTCAACCTGGTGGAGATCAG CCACTTGATCCTGAAAAGGATCCGGAGGGCTCTGAGAAGACCAGCAGAGGAGCAGATGGGGGAGGTGCCAGAGAAGCCC CTCCATGCTATTGCAGTGTCCTCCATCCCGAAGGCCAAAGGCTACAAGCTGCTAGAAGAAGAAAAGCCAGTGTCCCACT ATTTCCCTCTCACGGAAGTAGGGGTTGAGCCCAGTCCCCTTCCATCAGCCTTCAATGAGTTTGAGGAGAAGATTGGGAT GGGGCCACTGGAAGATCTCTCCAGGGCATTTGATGAGAGGTTACCATCGTATGCACAAGCGAAGGAACCGGAAGAGGAG AAGGTAAAAGCAGAGGAGGAAGAGGAACAAGAAGAGGAGCAGCAAGCACCTCAGGAAGAGCCAGGGGTGAAGAAAGCAG AGGAGGAGGTGGTGAGCGATGAAGTGGAAGGGCCTTCAGCACCTGCTGAACTTGCCACCGATGTGA

Stage

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Comments (click to highlight)

7-12

stage 12

Unlabeled

13-18

stage 16

stage 17

stage 18

Eye
Lens
Outflow Tract
Sinus Venosus
Ventricles

19-24

stage 23

stage 24

Eye

25-26

stage 26

Eye
Foregut
Head Mesenchyme
Lung
Sclerotome
Spinal Cord

Entry 2

GEISHA Id	CX45.6.Reza.2007	Data Source	Publication
Complete cDNA Template Probe	show ATGGGTGACTGGAGTTTCTTGGGGAACATTTTAGAGCAGGTGAACGAGCAGTCCACTGTCATCGGGAGAGTTTGGCTCA CGGTGCTCTTCATTTTCCGCATCCTGATCCTGGGAACAGCTGCTGAACTAGTATGGGGAGATGAACAGTCAGACTTTGT GTGCAACACCCAGCAACCTGGTTGTGAGAACGTCTGCTATGATGAGGCCTTCCCCATCTCCCACATCCGGCTCTGGGTC CTACAGATCATTTTTGTATCCACGCCTTCGCTAGTGTACTTTGGGCATGCGGTGCACCATGTCCGCATGGAGGAGAAGA GGAAAGAGAGGGAGGAAGCTGAGAGGCGTCAGCAAGCTGAGGTGGATGAAGAGAAGCTGCCCCTAGCTCCAAATCAAAA CAAGGGCAACAACCCAGATGGGACCAAGAAGTTTCGCCTGGAGGGGACCCTCCTGAGAACCTACATCCTCCACATCATT TTCAAAACTCTCTTTGAAGTGGGATTCATTGTTGGCCAGTATTTCCTGTATGGCTTCCGCATTCTCCCCCTTTACCGCT GTGGGCGGTGGCCCTGTCCCAACCTAGTGGACTGTTTTGTCTCCAGGCCCACAGAGAAGACCATCTTTATTATGTTCAT GCTCGTGGTGGCTGCTGTGTCCCTCTTCCTCAACCTGGTGGAGATCAGCCACTTGATCCTGAAAAGGATCCGGAGGGCT CTGAGAAGACCAGCAGAGGAGCAGATGGGGGAGGTGCCAGAGAAGCCCCTCCATGCTATTGCAGTGTCCTCCATCCCGA AGGCCAAAGGCTACAAGCTGCTAGAAGAAGAAAAGCCAGTGTCCCACTATTTCCCTCTCACGGAAGTAGGGGTTGAGCC CAGTCCCCTTCCATCAGCCTTCAATGAGTTTGAGGAGAAGATTGGGATGGGGCCACTGGAAGATCTCTCCAGGGCATTT GATGAGAGGTTACCATCGTATGCACAAGCGAAGGAACCGGAAGAGGAGAAGGTAAAAGCAGAGGAGGAAGAGGAACAAG AAGAGGAGCAGCAAGCACCTCAGGAAGAGCCAGGGGTGAAGAAAGCAGAGGAGGAGGTGGTGAGCGATGAAGTGGAAGG GCCTTCAGCACCTGCTGAACTTGCCACCGATGTGAGATCCCTCAGCAGGCTAAGTAAAGCCAGCAGCCGGGCCAGGTCA GACGATCTGACTGTATGA
Citation	Reza HM, Urano A, Shimada N, Yasuda K. Sequential and combinatorial roles of maf family genes define proper lens development. Mol Vis. 2007 Jan 16;13:18-30.
Copyright	This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Comments	As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc #NM_204997.1 )