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HPGDS
hematopoietic prostaglandin D synthase

Gene

Official Symbol	HPGDS
Official Full Name	hematopoietic prostaglandin D synthase
CGNC ID	49518
also known as	H-PGDS, PGDS, hematopoietic prostaglandin D synthase\|GST class-sigma\|glutathione S-transferase\|glutathione-dependent PGD synthase\|glutathione-dependent PGD synthetase\|glutathione-requiring prostaglandin D synthase\|prostaglandin-D synthase\|prostaglandin-H2 D-isomerase
gene type	protein-coding

Genomic Map

Sequence Information

Gene Expression

In Situ Hybridization

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly	36927			FBgn0010226
Human	27306	ENSG00000163106		MIM:602598
Mouse	54486	ENSMUSG00000029919	All phenotypic alleles (3):Targeted, knock-out(1) Targeted, other(2)	MGI:1859384
Xenopus	448666, 379417, 398969			944777
Zebrafish

Gene Ontology

Molecular Function	calcium ion binding, glutathione transferase activity, magnesium ion binding, more...
Biological Process	prostaglandin biosynthetic process, prostaglandin metabolic process
Cellular Component	cytoplasm, nucleus

Links to other databases

GEISHA Id	HPGDS.Anderson.2021	Data Source	Direct Submission
Complete cDNA Template Probe	show AGGGATCACACACCGCTGCACCCAAGGACCCATCATGCCCAACTACAAGCTGACGTACTTCAATCTGCGAGGAAGAGCA GAAATCTGCCGCTACCTGTTTGCCTATGCAGGCATAAAGTATGAAGACCACAGGTTGGAAGGAGCAGACTGGCCCAAAA TTAAACCAACTATCCCATTTGGCAAAGTTCCTATTCTGGAAGTAGATGGAGTGATCATTCACCAGAGCCTAGCAATTGC GAGATACCTCGCCAGAGAATCAGGTCTGGCAGGTCAGACTCCAGTGGAGCAGGCATTGGCTGATGCCATTGTGGACACC ATTGATGATTTCATGATGCTGTTCCCCTGGGCAGAGAAAAATCAGGATGTGAAGGAGAAAGCTTTTAATGACATCCTCA CCAACAAGGCCCCCGAGCTGCTAAAAGATTTGGATACTTTCTTAGGGGACAAGAAGTGGTTTGTAGGGAAATCTGTAAC ATGGGCTGATTTCTACTGGGATGTGTGCAGCACAACGCTCCTGTCCTACAAAGCTGACCTGGCAGACAAGTACCCCAGG CTGTTGGCTCTCAGGGACAGAGTGGAAGCACTGCCCGCTATTGCAGCCTGGATCCAGAAAAGACCAAAGACAGCAATTT AGACTGGCTGTTCAGTGGAAAAACAAATGCATGTTTTTTGGTTTTCAGACATTACAAGTGTGCTAAGTTATTAATTTTA GAATCATTTAAATTAATTTCAGGTGGATATGAAGTACCAAATCAGAATCTAGTAGAGTAGAGCCTGGGTAGAGGTGCCA TTCCAACTGCATTCCCTTCATCGCTAATAAAGTGTTTGGAAAA
Comments	Images and probe sequence provided by Claire Anderson. The probe was synthesized from cDNA clone ChEST153g19. Related paper: Anderson C, Hill B, Lu HC, Moverley A, Yang Y, Oliveira NMM, Baldock RA, Stern CD. A 3D molecular atlas of the chick embryonic heart. Dev Biol. 2019 Dec 1;456(1):40-46. doi: 10.1016/j.ydbio.2019.07.003. Epub 2019 Jul 5.

Stage

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7-12

stage 12

GEISHA Id	HPGDS.Anderson.2019	Data Source	Publication
Complete cDNA Template Probe	show GTGAAGGGATCACACACCGCTGCACCCAAGGACCCATCATGCCCAACTACAAGCTGACGTACTTCAATCTGCGAGGAAG AGCAGAAATCTGCCGCTACCTGTTTGCCTATGCAGGCATAAAGTATGAAGACCACAGGTTGGAAGGAGCAGACTGGCCC AAAATTAAACCAACTATCCCATTTGGCAAAGTTCCTATTCTGGAAGTAGATGGAGTGATCATTCACCAGAGCCTAGCAA TTGCGAGATACCTCGCCAGAGAATCAGGTCTGGCAGGTCAGACTCCAGTGGAGCAGGCATTGGCTGATGCCATTGTGGA CACCATTGATGATTTCATGATGCTGTTCCCCTGGGCAGAGAAAAATCAGGATGTGAAGGAGAAAGCTTTTAATGACATC CTCACCAACAAGGCCCCCGAGCTGCTAAAAGATTTGGATACTTTCTTAGGGGACAAGAAGTGGTTTGTAGGGAAATCTG TAACATGGGCTGATTTCTACTGGGATGTGTGCAGCACAACGCTCCTGTCCTACAAAGCTGACCTGGCAGACAAGTACCC CAGGCTGTTGGCTCTCAGGGACAGAGTGGAAGCACTGCCCGCTATTGCAGCCTGGATCCAGAAAAGACCAAAGACAGCA ATTTAGACTGGCTGTTCAGTGGAAAAACAAATGCATGTTTTTTGGTTTTCAGACATTACAAGTGTGCTAAGTTATTAAT TTTAGAATCATTTAAATTAATTTCAGGTGGATATGAAGTACCAAATCAGAATCTAGTAGAGTAGAGCCTGGGTAGAGGT GCCATTCCAACTGCATTCCCTTTCATCGCTAATAAAGTGTTTGGAAAAACGAAAA
Citation	Anderson C, Hill B, Lu HC, Moverley A, Yang Y, Oliveira NMM, Baldock RA, Stern CD. A 3D molecular atlas of the chick embryonic heart. Dev Biol. 2019 Dec 1;456(1):40-46. doi: 10.1016/j.ydbio.2019.07.003. Epub 2019 Jul 5.
Copyright	Copyright © 2019 Elsevier Inc. All rights reserved.
Comments	The complete cDNA template sequence was obtained from the information from the publication as described in Anderson et al. 2019.