GEISHA - A Chicken Embryo Gene Expression Database
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DIO3
iodothyronine deiodinase 3

Gene
Official SymbolDIO3
Official Full Nameiodothyronine deiodinase 3
CGNC ID49561
also known asthyroxine 5-deiodinase|5DIII|DIOIII|deiodinase, iodothyronine type III|type 3 DI|type III iodothyronine deiodinase|type-III 5'-deiodinase
gene typeprotein-coding
Genomic Map
 Ensembl ID not known
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
RNANM_001122648
PolypeptideNP_001116120
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST ProfileGga.552
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly
Human1735ENSG00000197406MIM:601038
Mouse107585ENSMUSG00000075707All phenotypic alleles (2):Targeted, knock-out(2) MGI:1306782
Xenopus100038242, 397779487489
Zebrafish100538339ZDB-GENE-070705-53, ZDB-GENE-120406-7ZFIN:ZDB-GENE-070705-53, ZFIN:ZDB-GENE-120406-7
Gene Ontology
Molecular Functionthyroxine 5-deiodinase activity, thyroxine 5'-deiodinase activity
Biological Processhormone biosynthetic process
Cellular Componentendosome membrane, integral component of membrane, plasma membrane
Links to other databases
Entrez Gene395939
Ensembl Gene
KEGGgga:395939
GEISHA IdDIO3.Roy.2013Data SourcePublication
Complete cDNA Template Probeshow
ATGCTCCACTCGCTGGGCGCTCACACCTTGCAGCTGCTCACCCAGGCGGCCGCCTGCATCCTCCTCTTTCCCCGCTTCC
TGCTCACCGCTGTGATGCTCTGGCTCCTGGATTTTCTGTGCATTCGCAAGAAGATGCTGACGATGCCCACGGCGGAGGA
GGCGGCCGGAGCCGGCGAGGGGCCGCCCCCCGACGACCCTCCGGTCTGCGTGTCCGACTCCAACCGCATGTTCACGCTG
GAGTCGCTCAAGGCCGTGTGGCACGGGCAGAAGCTGGACTTCTTCAAGTCGGCGCACGTGGGCTCGCCTGCCCCCAACC
CCGAGGTGATCCAGCTGGACGGGCAGAAGAGGCTCCGCATCCTCGACTTCGCCCGCGGCAAGAGGCCCCTCATCCTCAA
CTTCGGCAGCTGCACCTGACCCCCGTTCATGGCCCGCCTGAGGTCCTTCCGGCGCCTGGCCGCGCACTTCGTGGACATT
GCCGACTTCCTGCTGGTGTACATCGAAGAAGCGCACCCCTCCGACGGCTGGGTCAGCTCGGACGCTGCCTACAGCATCC
CCAAGCACCAGTGCCTCCAGGACAGGCTGCGGGCGGCGCAGCTGATGCGGGAAGGGGCGCCCGATTGCCCCCTGGCCGT
GGACACCATGGACAACGCTTCCAGCGCTGCCTACGGCGCCTACTTCGAGCGGCTCTACGTCATCCAGGAGGAGAAGGTG
ATGTACCAGGGCGGCCGAGGACCGGAGGGCTACAAGATCTCGGAGCTGCGGAGCTGGCTAGACCAGTACAAAACCCGGC
TCCAGAGCCCCGGCGCGGTGGTCATCCAAGTGTAAAAAGGACCCGGCAGAAGGCGCGGGGGGAGAGGGGAGGGCGGGCG
GAGGAACGCGGGGGGGCTCCGCGCCGGGGCTGCGTGCGGGCGAGATGTGCCATAGTCCTTTCTCTATTCAAATCATGTT
GATTTGCCAGCCACGCTCTGTCAATACTGTATTTCCATGTGCGTTTTGTAAATAACTCCTTTTTTTTTCTTTTTTCTTT
TTTTTTTTTTTCTTTCCTTTTGAGAAGCGTTTACTATTTTTTAAGGAGGCTCTCTTCCTTCGGGATCTGTTCCCAGCTG
CGTGTGTGCGCGGGTGTGTGTCTGAAAAGTTGTGTACAAGTGCTCCGTGCTGCCTAGCAAGTGCTAACTGGGATTTCTA
GTATTTCTTTGTGATGACCGATTTTGAAATGGGTTTCTCTAATGCCAGGAAATCGTGTCTGATGTTGTCAAGTACTAGA
ACTGCCAATAGCCAGAGCTGAACGGAATGTCCTATTTATGGGGGGGGTTTTGTAAGACGTTCGTTCACCTTTTTTTTTT
TTAATGAATTTTTTAAAATAATAAAGGTTGAGTAAATACATAAAAAAAAAAAAAAAAAAAAAAAAA
CitationRoy P, Kumar B, Shende A, Singh A, Meena A, Ghosal R, Ranganathan M, Bandyopadhyay A. A Genome-Wide Screen Indicates Correlation between Differentiation and Expression of Metabolism Related Genes. PLoS One. 2013 May 22;8(5):e63670
CopyrightThis is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
CommentsAs insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI NM_001122648.1
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
13-18
stage 18
stage 18
Eye
Mesonephros
 
19-22
stage 22
stage 22
Cranial PNS
Eye
Somites
Spinal Ganglia and Nerves
 
 Data from NCBI Unigene EST Profile
Unigene ID: Gga.552

Mouse

EmageMGI:1306782
EurexpressMGI:1306782
MGI GXDMGI:1306782

Frog

Xenbase487489

Fruit Fly

BDGP

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-070705-53, ZDB-GENE-120406-7
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