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HOXA2 Gene Summary Expression Transcript Levels Other Species Expression JBrowse Gene Official Symbol HOXA2 Official Full Name homeobox A2 CGNC ID 49629 also known as homeobox protein Hox-A2 gene type protein-coding
Genomic Map Sequence Information Gene Expression Orthology Entrez Gene Ensembl Gene Genetic Phenotypes MOD Fruit Fly Human Mouse Xenopus Zebrafish
Gene Ontology Molecular Function sequence-specific DNA binding , sequence-specific DNA binding transcription factor activity Biological Process anterior/posterior pattern specification , brain segmentation , cell fate determination , more... dorsal/ventral pattern formation , embryonic viscerocranium morphogenesis , middle ear morphogenesis , motor neuron axon guidance , negative regulation of neuron differentiation , negative regulation of transcription from RNA polymerase II promoter , osteoblast development , positive regulation of transcription from RNA polymerase II promoter , rhombomere 2 development , rhombomere 3 morphogenesis , segment specification , transcription, DNA-templated Cellular Component nucleus
Links to other databases
Entry 1 GEISHA Id HOXA1.Paxton.2010 Data Source Publication Complete cDNA Template Probe show ATGAATTTCGAATTCGAGCGAGAGATCGGTTTTATCAATAGTCAGCCATCGCTTGCTGAGTGCCTGACATCTTTTCCCC
Citation Paxton CN, Bleyl SB, Chapman SC, Schoenwolf GC.
Identification of differentially expressed genes in early inner ear development. Gene Expr Patterns. 2010 Jan;10(1):31-43. Epub 2009 Nov 11.
Copyright 2009 Elsevier B.V. All rights reserved. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc # XM_001234919).
Entry 2 GEISHA Id HOXA2.Paxton.2010 Data Source Publication Complete cDNA Template Probe show TCTTTTTTTCTCCTCTCTCTCCTTTTTCCCGGGCCTTCCCCCCCCGAGCCCCCGGCATCCGGGGGAACTTTTTCTCCGC
Citation Paxton CN, Bleyl SB, Chapman SC, Schoenwolf GC.
Identification of differentially expressed genes in early inner ear development. Gene Expr Patterns. 2010 Jan;10(1):31-43. Epub 2009 Nov 11.
Copyright 2009 Elsevier B.V. All rights reserved. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc # NM_205150.1).
Entry 3 GEISHA Id HOXA2.Tossell.2011 Data Source Publication Complete cDNA Template Probe show TCTTTTTTTCTCCTCTCTCTCCTTTTTCCCGGGCCTTCCCCCCCCGAGCCCCCGGCATCCGGGGGAACTTTTTCTCCGC
Citation Tossell K, Kiecker C, Wizenmann A, Lang E, Irving C.
Notch signalling stabilises boundary formation at the midbrain-hindbrain organiser. Development. 2011 Sep;138(17):3745-57. Epub 2011 Jul 27.
Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc # NM_205150.1).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 7-10 stage 10
stage 10
stage 10
stage 10
Isthmus/MHB Rhombomeres
Entry 4 GEISHA Id HOXA2.Lorente-Cánovas.2012 Data Source Publication Complete cDNA Template Probe show TCTTTTTTTCTCCTCTCTCTCCTTTTTCCCGGGCCTTCCCCCCCCGAGCCCCCGGCATCCGGGGGAACTTTTTCTCCGC
Citation Lorente-Cánovas B, Marín F, Corral-San-Miguel R, Hidalgo-Sánchez M, Ferrán JL, Puelles L, Aroca P. Multiple origins, migratory paths and molecular profiles of cells populating the avian interpeduncular nucleus. Dev Biol. 2012 Jan 1;361(1):12-26. Copyright Copyright © 2011 Elsevier Inc. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc # NM_205150.1).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 25-30 stage 26
stage 26
stage 26
Rhombomeres 31-38 stage 38
Isthmus/MHB Rhombomeres
Entry 5 GEISHA Id HOXA2.Giudicelli.2001 Data Source Publication Complete cDNA Template Probe show TCTTTTTTTCTCCTCTCTCTCCTTTTTCCCGGGCCTTCCCCCCCCGAGCCCCCGGCATCCGGGGGAACTTTTTCTCCGC
Citation Giudicelli F, Taillebourg E, Charnay P, Gilardi-Hebenstreit P. Krox-20 patterns the hindbrain through both cell-autonomous and non cell-autonomous mechanisms. Genes Dev. 2001 March 1; 15(5): 567580. Copyright Copyright © 2001, Cold Spring Harbor Laboratory Press Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # NM_205150.1).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 13-17 stage 17
stage 17
Rhombomeres
Entry 6 GEISHA Id HOXA2.Richardson.2011 Data Source Publication Complete cDNA Template Probe show TTTTTTTCTCCTCTCTCTCCTTTTTCCCGGGCCTTCCCCCCCCGAGCCCCCGGCATCCGGGGGAACTTTTTCTCCGCGG
Citation Richardson J, Shono T, Okabe M and Graham A. The presence of an embryonic opercular flap in amniotes. PLoS One. 2012; 7(9): e44903. Published online 2012 September 11. Copyright PLoS One. 2012; 7(9): e44903. Published online 2012 September 11. Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # NM_205150.2).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 25-26 stage 26
stage 26
Pharyngeal Arches and Clefts
Entry 7 GEISHA Id HoxA2.Martinez.2018 Data Source Publication Complete cDNA Template Probe show TTTTTTTCTCCTCTCTCTCCTTTTTCCCGGGCCTTCCCCCCCCGAGCCCCCGGCATCCGGGGGAACTTTTTCTCCGCGG
Citation Martinez D, Zuhdi N, Reyes M, Ortega B, Giovannone D, Lee VM, de Bellard ME. Screen for Slit/Robo signaling in trunk neural cells reveals new players. Gene Expr Patterns. 2018 Jun;28:22-33. Epub 2018 Feb 7. DIO: 10.1016/j.gep.2018.01.002. Copyright Copyright © 2018 The Authors. Published by Elsevier B.V. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence was obtained from NCBI (NM_205150)
Entry 8 GEISHA Id HOXA2.Anderson.2021 Data Source Direct Submission Complete cDNA Template Probe show GGAGAGGACGTCTTTAATTTCTCAGTAATTCAGATGCTGTAAGTCAATCGTGGTGAGCGTGTCTGTAAAAAAGTCAAAG
Comments Images and probe sequence provided by Claire Anderson. The probe was synthesized from cDNA clone ChEST671c8. Related paper: Anderson C, Hill B, Lu HC, Moverley A, Yang Y, Oliveira NMM, Baldock RA, Stern CD. A 3D molecular atlas of the chick embryonic heart. Dev Biol. 2019 Dec 1;456(1):40-46. doi: 10.1016/j.ydbio.2019.07.003. Epub 2019 Jul 5.
Entry 9 Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 7-12 stage 12
stage 12
Heart
Entry 10 GEISHA Id HOXA2.Trevers.2023 Data Source GEISHA ISH Analysis Complete cDNA Template Probe show AGGATGAAGCACAAGAGGCAGACCCAGTGCAAGGAGAACCAGAACGGCGAGGGGAAATTTAAGGGCTCGGAGGACCCCG
Comments The complete cDNA template sequence was obtained from the information from the publication as described in Trevers et al. 2023.
Data from NCBI Unigene EST ProfileGga.524
Mouse Frog Fruit Fly Zebra Finch Zebrafish
