GEISHA - A Chicken Embryo Gene Expression Database
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NTRK2
neurotrophic receptor tyrosine kinase 2

The human orthologue of this gene is associated
with the following human disease:
Gene
Official SymbolNTRK2
Official Full Nameneurotrophic receptor tyrosine kinase 2
CGNC ID49676
also known asTRKB, BDNF/NT-3 growth factors receptor|neurotrophic tyrosine kinase, receptor, type 2|trk-B|trkB tyrosine kinase|tyrosine kinase receptor
gene typeprotein-coding
Genomic Map
 Ensembl ID not known
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
RNANM_205231
PolypeptideNP_990562
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST ProfileGga.681
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly
Human4915ENSG00000148053MIM:613886MIM:600456
Mouse18212ENSMUSG00000055254All phenotypic alleles (16):Targeted, knock-out(4) Targeted, other(12) MGI:97384
Xenopus780110, 779173, 379266922931
Zebrafish100331394, 65090, 570240ENSDARG00000059897, ENSDARG00000059645ZDB-GENE-010126-3, ZDB-GENE-010126-1, ZDB-GENE-010126-2ZFIN:ZDB-GENE-010126-3, ZFIN:ZDB-GENE-010126-1, ZFIN:ZDB-GENE-010126-2
Gene Ontology
Molecular FunctionATP binding, brain-derived neurotrophic factor-activated receptor activity, more...brain-derived neurotrophic factor binding, neurotrophin binding, protein homodimerization activity
Biological Processbrain-derived neurotrophic factor receptor signaling pathway, more...central nervous system neuron development, cerebral cortex development, learning, negative regulation of neuron apoptotic process, neuron differentiation, neuron migration, positive regulation of axonogenesis, positive regulation of cell proliferation, positive regulation of gene expression, positive regulation of MAPK cascade, positive regulation of neuron projection development, positive regulation of phosphatidylinositol 3-kinase signaling, protein autophosphorylation, regulation of Rac GTPase activity
Cellular Componentendosome membrane, integral component of plasma membrane
Links to other databases
Entrez Gene396157
Ensembl Gene
KEGGgga:396157

Entry 1

GEISHA IdNTRK2.UApcrData SourceGEISHA ISH Analysis
Forward cDNA Template PrimerTCCAAGAAGCCTTTTCGCC
Reverse cDNA Template PrimerATTAACCCTCACTAAAGGGGACCTTTCATCCCAAACTTAGAGcDNA Template Length1001
Forward cDNA Template Probeshow
AACTTCAGAATAATGGAGCATTATTACTAAGCCAGGTGCATACCAGTGCTGCAATTCCCACCACAACGTACACAGTGAT
GCTATCTTCATTCTCTTTGTTGGAAACATCCGGAGAAGTGATTTGATTACTGTTATTTGTGGTGTCTCCAAGATCATTA
GGCGTGGTTTCATATTCATAAACGTCTGGATCCACAATTGGGCCACTACCATCTCCAGGCACTGACATGAAATGAGCAT
CAACCCGCTTTTCATCCTCTCCATACTCATTCTTGGCCAGTAAGGTATAAGCACCATTGTTCAGGTGGGTAGGGTTGTC
CAGCTGAAGGCAGCCATGGTATTCACTTTGATTGATAACATGTATTTTAGTACAGATGTATTCAGACTCATTCAATATA
GCTCCTTCATAGAACCACTGCAATGTGGGCTTAGGGTTCCCTTTCACAGTGAATGGAATGCACCAGTGGTGGTCCGGGG
TTGGAGATTCAATAAAAGTGATATTTGGTGCAAAGAATACCGTCAGTTCGGCAGAGGTTTGGACCTCTCCCACAATGTT
CTCCGCCACACACGAAATCCACAGTCCGCTGTCCATGGACGAAACATTCTTTATGGTTAACGAGGCAGGATTCTTACTT
GTGTCACTCTCATGGTTTGAAACAAGGTTAGTGAGCACCCAGGACACATTAGGGGGTGGCCCTCCGGTTGTATCACAGT
ACAGTGTGATGCTCTTTCCTTCCACCACAGTGATGTTGTAATTGCTTAAGTTTGCTGATGGTAAGTCGCAGTTTGGGAC
CTTCATATCCATCAGGGCTATTCGCTTGTTATTGTCATCTACACAGTATATATCCTGAGCTTCTGTGTAAAACTTGGTC
TCTTGNAAATTTCTTAATCCACATAATTTCACAGGAACACTTGAATGGATTGTCCACCAGTATCAGATCANACAAACCC
AGATGGCGAAA
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
7-12
stage 9
stage 10
stage 11
Forebrain
Hindbrain
Midbrain
Rhombomeres
Spinal Cord
 
13-18
stage 14
stage 15
stage 15
stage 15
stage 16
stage 17
stage 17
stage 17
stage 17
stage 17
Head Mesenchyme
Heart
Hindbrain
Liver
Midbrain
Notochord
Oral Pharynx
Spinal Cord
 
19-24
stage 19
stage 19
stage 21
stage 21
stage 22
stage 22
stage 23
stage 23
stage 23
stage 23
Head Mesenchyme
Hindbrain
Hindgut
Liver
Mesonephros
Midbrain
Notochord
Oral Pharynx
Spinal Cord
Spinal Ganglia and Nerves
 
25-26
stage 26
stage 26
  

Entry 2

GEISHA IdTRKB.Yang.2010Data SourcePublication
Complete cDNA Template Probeshow
TTGTGCTGCCTGGTGCTGGGTTGCTGGCGGGGCGCGCTGGGCTGCCCCGCGTCCTGTCGCTGCAGTTCCTGGCGGATCT
GGTGCTCGGAGCCCGTGCCCGGCATCACCTCCTTCCCCGTGCCGCAGCGGAGCACCGAGGATGACAATGTCACCGAGAT
TTACATCGCAAACCAGCGAAAATTAGAAAGTATCAATGACAATGAAGTTGGATTTTACGTTGGACTTAAAAATCTGACT
GTGGTGGATTCAGGCTTAAGATTTGTGTCCCGTCAGGCATTTGTGAAAAACATCAACCTACAATACATCAATTTATCTA
GAAACAAGCTCTCAAGTTTGTCCAAGAAGCCTTTTCGCCATCTGGGTTTGTCTGATCTGATACTGGTGGACAATCCATT
CAAGTGTTCCTGTGAAATTATGTGGATTAAGAAATTTCAAGAGACCAAGTTTTACACAGAAGCTCAGGATATATACTGT
GTAGATGACAATAACAAGCGAATAGCCCTGATGGATATGAAGGTCCCAAACTGCGACTTACCATCAGCAAACTTAAGCA
ATTACAACATCACTGTGGTGGAAGGAAAGAGCATCACACTGTACTGTGATACAACCGGAGGGCCACCCCCTAATGTGTC
CTGGGTGCTCACTAACCTTGTTTCAAACCATGAGAGTGACACAAGTAAGAATCCTGCCTCGTTAACCATAAAGAATGTT
TCGTCCATGGACAGCGGACTGTGGATTTCGTGTGTGGCGGAGAACATTGTGGGAGAGGTCCAAACCTCTGCCGAACTGA
CGGTATTCTTTGCACCAAATATCACTTTTATTGAATCTCCAACCCCGGACCACCACTGGTGCATTCCATTCACTGTGAA
AGGGAACCCTAAGCCCACATTGCAGTGGTTCTATGAAGGAGCTATATTGAATGAGTCTGAATACATCTGTACTAAAATA
CATGTTATCAATCAAAGTGAATACCATGGCTGCCTTCAGCTGGA
CitationYang M, Cagle MC, Honig MG. Identification of cerebellin2 in chick and its preferential expression by subsets of developing sensory neurons and their targets in the dorsal horn. J Comp Neurol. 2010 Jul 15;518(14):2818-40.
CopyrightCopyright © 2010 Wiley-Liss, Inc.
CommentsThe cDNA template used to generate the probe was obtained by PCR as described in Yang et al.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
25-30
stage 30
stage 30
Spinal Cord
Spinal Ganglia and Nerves
 
 Data from NCBI Unigene EST Profile
Unigene ID: Gga.681

Mouse

EmageMGI:97384
EurexpressMGI:97384
MGI GXDMGI:97384

Frog

Xenbase922931

Fruit Fly

BDGP

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-010126-3, ZDB-GENE-010126-1, ZDB-GENE-010126-2
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