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NPM1
nucleophosmin

The human orthologue of this gene is associated
with the following human disease:

Gene

Official Symbol	NPM1
Official Full Name	nucleophosmin
CGNC ID	49698
also known as	NO38, nucleophosmin\|NPM\|nucleolar phosphoprotein B23\|nucleolar protein NO38\|nucleophosmin (nucleolar phosphoprotein B23, numatrin)\|numatrin, Nucleophosmin (NPM), Nucleolar phosphoprotein B23, Numatrin, Nucleolar protein NO38
gene type	protein-coding

Genomic Map

Sequence Information

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.4847

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly
Human	4869	ENSG00000181163	MIM:601626	MIM:164040
Mouse	18148	ENSMUSG00000057113	All phenotypic alleles (5):Targeted, knock-out(1) Targeted, other(2) Gene trapped(2)	MGI:106184
Xenopus	394478, 379194			1019570
Zebrafish	266985, 553507	ENSDARG00000014329	ZDB-GENE-021028-1, ZDB-GENE-080723-7	ZFIN:ZDB-GENE-021028-1, ZFIN:ZDB-GENE-080723-7

Gene Ontology

Molecular Function	NF-kappaB binding, RNA binding, unfolded protein binding
Biological Process	cell aging, centrosome cycle, DNA repair, negative regulation of cell proliferation, more...
Cellular Component	centrosome, cytoplasm, nucleolus, nucleoplasm, nucleus

Links to other databases

GEISHA Id	V23	Data Source	GEISHA ISH Analysis
Forward cDNA Template Probe	show GGTCCGCAGCGCCGCATCCCGTACAGCTCCTCCCGCGCGAGCAGGCCGAGAAGATGGAGGACAGCGCCATGGACATGGA GAGCATGGGCCCGCTGCGCCCGCAGACCTTCCTCTTCGGCTGCGAGCTTAAAGCAGAGAAGGAATATCAGTTCAAAGTA GATGATGAGGAAAACGAGCATCAGCTGTCCTTGAGAACGGTTACATTAGGGGCTGGAGCCAAAGACGAATTACATGTTG TAGAAGCAGAAGCACTGGACTATGAAGGCAACCCAACTAAAGTAGTACTGGCATCTCTGAAAATGTCTGTGCAGCCTAC AGTTTCACTAGGTGGATTTGAGATCACACCACCAGTTGTCCTGAGGTTAAAATGTGGTTCGGGGCCTGTTTATGTCAGT GGTCAGCATCTTGTAGCATTAGAGGAAGAGCCAGAATCAGAGGATGAGGAGGAGGATACAAAAATAGGGAATGCTTCAA CAAAGAGACCAGCAAGTGGAGGAGGAGCTAAAACACCACAGAAAAAACCAAAATTATCAGAAGATGATGAGGACGATGA TT
Comments	no specific expression detected, stages 4-9, ubiquitous

no images

GEISHA Id	B33	Data Source	GEISHA ISH Analysis
Forward cDNA Template Probe	show `GGTCCGCAGCGCCGCATCCCGTACAGCTCCTCCCGCGCGAGCAGGCCGAGAAGATGGAGGACAGCGCCATGGACATGGA GAGCATGGGCCCGCTGCGCCCGCAGACCTTCCTCTTCGGCTGCGAGCTTAAAGCAGAGAAGGAATATCAGTTCAAAGTA GATGATGAGGAAAACGAACATCAGCTGTCCTTGAGAACGGTTACATTAGGGGCTGGAGCCAAAGACGAATTACATGTTG TAGAAGCAGAAGCACTGGACTACGAAGGCAACCCAACTAAAGTAGTACTGGCATCTCTGAAAATGTCTGTGCAGCCTAC AGTTTCACTAGGTGGATTTGAGATCACACCACCAGTTGTCTTGAGGTTAAAATGTGGTTCGGGGCCTGTTTATGTCAGT GGTCAGCATCTTGTAGCATTAGAGGAAGAGCCAGAATCAGAGGATGAGGAGGAGGATACAAAAATAGGGAATG`

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

13-15

stage 15

Data from NCBI Unigene EST Profile
Unigene ID: Gga.4847