Geisha

home

contact

A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

Quick Search

Data Class

Enter Text:

Gene Family QuickSearch

	Transcription Factors
	Growth Factors
	Receptors
	MicroRNAs

Human Disease Gene Search

	Downloads
	Protocols
	About GEISHA
	Contact Us

	Transgenic Birds
	Model Organism Databases
	Gene Expression Databases
	Genomic Resources
	Anatomical Atlases
	Chicken Stage Series

TTR
transthyretin

The human orthologue of this gene is associated
with the following human diseases:

Gene

Official Symbol	TTR
Official Full Name	transthyretin
CGNC ID
also known as	transthyretin\|TBPA\|prealbumin, Transthyretin, Prealbumin, Ttr, TBPA
gene type	protein-coding

Genomic Map

	Ensembl
	NCBI
	UCSC
	Gallus-Browse

Sequence Information

Genomic
RNA	NM_205335
Polypeptide	NP_990666
Sequence Clusters/ESTs	Unigene

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.2620

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly
Human	7276	ENSG00000118271	MIM:176300	MIM:176300
Mouse	22139	ENSMUSG00000061808	All phenotypic alleles (7):Targeted, knock-out(2) Targeted, other(5)	MGI:98865
Xenopus	100125183, 397787			479394
Zebrafish	449556	ENSDARG00000037191	ZDB-GENE-040927-14	ZFIN:ZDB-GENE-040927-14

Gene Ontology

Molecular Function	binding, hormone activity, identical protein binding, protein binding, protein domain specific binding
Biological Process	oocyte growth, protein complex assembly, response to virus, transport
Cellular Component	clathrin-coated vesicle, extracellular space, macromolecular complex, yolk

Links to other databases

Entrez Gene	396277
Ensembl Gene	ENSGALG00000015143
KEGG	gga:396277

Entry 1

GEISHA Id	Transthyretin.Yanai.2005	Data Source	Publication
Complete cDNA Template Probe	show CCACAACTCACTAACAGCAAACAGAATGGCCTTTCACTCTACTCTTCTTGTTTTCTTAGCTGGACTGGTATTTCTCTCC GAAGCTGCACCACTGGTCTCCCATGGCTCTGTTGATTCCAAATGCCCTCTCATGGTGAAAGTGCTGGATGCAGTCAGAG GAAGTCCTGCAGCTAACGTAGCTGTTAAAGTCTTTAAAAAGGCTGCAGATGGAACCTGGCAGGACTTTGCTACTGGGAA AACCACAGAGTTCGGTGAAATCCATGAGCTCACAACAGAAGAACAGTTTGTAGAAGGAGTATACAGAGTTGAGTTTGAC ACCAGTTCTTACTGGAAGGGACTTGGCCTTTCCCCATTCCATGAATATGCTGATGTGGTGTTCACTGCTAATGATTCTG GCCACCGCCATTATACCATCGCTGCTCTCCTCAGTCCTTTCTCTTACTCAACAACTGCTGTTGTCAGTGATCCCCAGGA ATGAAAACATACTGTCAATAGATATATATACCCTCCTCTGCTAGGACTATTATAGGTTTTTAGGAGGAAGGTTTTTCCG ATTGCTAATGCATATCCTTTTGCTACATTAGTTGTTATTTGTTTTTCATTTTGTAACCTGGCAAAAATTCAGACAAGTC AATAAAATGTAACTTCTTTAAAACAAAAAAAAAAAAAA
Citation	Yanai M, Tatsumi N, Endo F, Yokouchi Y. Analysis of gene expression patterns in the developing chick liver. Dev Dyn. 2005 Jul;233(3):1116-22.
Copyright	Wiley-Liss, Inc. 2005
Comments	Authors indicate probe information can be found in (Duan et al., 1991), which is unavailable online. The sequence below was obtained from NCBI (acc # NM_205335).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

7-12

stage 12

Anterior Intestinal Portal
Endoderm, early
Yolk Sack or Stalk

13-18

stage 17

Liver
Pancreas
Yolk Sack or Stalk

19-24

stage 22

Liver
Pancreas
Yolk Sack or Stalk

25-30

stage 25

stage 30

Anterior Intestinal Portal
Liver
Pancreas

31-42

stage 42

Liver

Entry 2

GEISHA Id	Ttr.vonFrowein.2006	Data Source	GEISHA ISH Analysis
Complete cDNA Template Probe	show CCACAACTCACTAACAGCAAACAGAATGGCCTTTCACTCTACTCTTCTTGTTTTCTTAGCTGGACTGGTATTTCTCTCC GAAGCTGCACCACTGGTCTCCCATGGCTCTGTTGATTCCAAATGCCCTCTCATGGTGAAAGTGCTGGATGCAGTCAGAG GAAGTCCTGCAGCTAACGTAGCTGTTAAAGTCTTTAAAAAGGCTGCAGATGGAACCTGGCAGGACTTTGCTACTGGGAA AACCACAGAGTTCGGTGAAATCCATGAGCTCACAACAGAAGAACAGTTTGTAGAAGGAGTATACAGAGTTGAGTTTGAC ACCAGTTCTTACTGGAAGGGACTTGGCCTTTCCCCATTCCATGAATATGCTGATGTGGTGTTCACTGCTAATGATTCTG GCCACCGCCATTATACCATCGCTGCTCTCCTCAGTCCTTTCTCTTACTCAACAACTGCTGTTGTCAGTGATCCCCAGGA ATGAAAACATACTGTCAATAGATATATATACCCTCCTCTGCTAGGACTATTATAGGTTTTTAGGAGGAAGGTTTTTCCG ATTGCTAATGCATATCCTTTTGCTACATTAGTTGTTATTTGTTTTTCATTTTGTAACCTGGCAAAAATTCAGACAAGTC AATAAAATGTAACTTCTTTAAAACAAAAAAAAAAAAAA
Comments	Authors said: Plasmid templates were used to generate digoxygenin antisense riboprobes: Ttr (M. Wassef) (Duan et al., 1991). As information provided was insufficient to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # NM_205335).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

25-28

stage 28

choroid plexus

Entry 3

GEISHA Id	TTR.Barron.1998	Data Source	Publication
Complete cDNA Template Probe	show `TTCTCTCCGAAGCTGCACCACTGGTCTCCCATGGCTCTGTTGATTCCAAATGCCCTCTCATGGTGAAAGTGCTGGATGC AGTCAGAGGAAGTCCTGCAGCTAACGTAGCTGTTAAAGTCTTTAAAAAGGCTGCAGATGGAACCTGGCAGGACTTTGCT ACTGGGAAAACCACAGAGTTTGGTGAAATCCATGAGCTCACAACAGAAGAACAGTTTGTAGAAGGAGTATACAGAGTTG AGTTTGACACCAGTTCTTACTGGAAGGGACTTGGCCTTTCCCCATTCCATGAATATGCTGATGTGGTGTTCACTGCTAA TGATTCTGGCCACCGCCATTATACCATCGCTGCTCTCCTCAGTCCT`
Citation	Barron M, McAllister D, Smith SM, Lough J. Expression of retinol binding protein and transthyretin during early embryogenesis. Dev Dyn. 1998 Jul;212(3):413-22.
Copyright	Copyright © 1998 Wiley‐Liss, Inc.
Comments	The complete cDNA template sequence was obtained from the information from the publication as described in Barron al. 1998.