GEISHA - A Chicken Embryo Gene Expression Database
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PTHLH
parathyroid hormone like hormone

The human orthologue of this gene is associated
with the following human disease:
Gene
Official SymbolPTHLH
Official Full Nameparathyroid hormone like hormone
CGNC ID12993
also known asPTHrP, parathyroid hormone-related protein|PTH-rP
gene typeprotein-coding
Genomic Map
 Ensembl
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
RNANM_001174106
PolypeptideNP_001167577
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST ProfileGga.2626
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly
Human5744ENSG00000087494MIM:613382MIM:168470
Mouse19227ENSMUSG00000048776All phenotypic alleles (8):Targeted, knock-out(3) Targeted, other(5) MGI:97800
Xenopus100462910959053
Zebrafish554221, 100536439ENSDARG00000031737ZDB-GENE-050119-9, ZDB-GENE-110411-206ZFIN:ZDB-GENE-050119-9, ZFIN:ZDB-GENE-110411-206
Gene Ontology
Molecular Functionhormone activity, peptide hormone receptor binding
Biological Processadenylate cyclase-activating G-protein coupled receptor signaling pathway, more...positive regulation of cAMP biosynthetic process, regulation of chondrocyte differentiation, regulation of gene expression, skeletal system development
Cellular Componentcytoplasm, extracellular region, nucleus
Links to other databases
Entrez Gene396281
Ensembl GeneENSGALG00000017295
KEGGgga:396281

Entry 1

GEISHA IdPTHLP.Roddy.2011Data SourcePublication
Complete cDNA Template Probeshow
GGTTTAAGCCCCGGAGGATATGATGTTCACGAAACTCTTTCAGCAGTGGAGTTTCGCGGTGTTTCTTCTGAGTTATTCT
GTGCCCTCCTACGGAAGATCAGTAGAGGGGATCAGCCGCAGACTCAAACGGGCCGTATCAGAGCACCAGCTACTGCATG
ACAAGGGCAAATCAATCCAAGACTTACGAAGAAGGATATTCCTTCAAAATTTAATTGAAGGTGTCAACACTGCAGAAAT
CCGTGCAACTTCAGAGGTCTCACCTAACCCTAAGCCTGCTACCAACACAAAGAACTACCCTGTCCGTTTTGGCAGTGAA
GATGAGGGCAGATACTTAACTCAGGAGACAAACAAATCACAGACCTACAAGGAACAGCCCCTGAAGGTATCAGGGAAGA
AAAAGAAAGCGAAGCCTGGAAAACGTAAAGAACAAGAGAAGAAAAAGAGGCGAGCTCGCTCAGCTTGGCTAAATTCTGG
CATGTATGGAAGCAATGTAACTGAGAGCCCAGTCTTGGACAACTCTGTTACTACACATAATCATATTTTAAGGAGGCGC
TGATATTTTCAGCAAGACAGCTTTGGAAGACATATTGCAGTATTCTGTAATAGTGAACATAGAACATATGGGAAGTATA
AAAATATTTATTACCTGTAAATATTGTAAATGCTC
CitationRoddy KA, Prendergast PJ, Murphy P. Mechanical influences on morphogenesis of the knee joint revealed through morphological, molecular and computational analysis of immobilised embryos. PLoS One. 2011 Feb 28;6(2):e17526.
CopyrightPLoS One is an open access journal.
CommentsThe cDNA template used to generate the probe was obtained from EST - ChEST533c1 as described.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
25-27
stage 27
stage 27
stage 27
Leg Mesenchyme
par, periarticular
par, periarticular

Entry 2

GEISHA IdPTHrP.Zou.1997Data SourceGEISHA ISH Analysis
Complete cDNA Template Probeshow
ACTAGCGTACAATTAACATCATTAGGAATCAGCCCTCCAGCTAACAGAGGAACTGCGACGAACAACGGTTTAAGCCCCG
GAGGATATGATGTTCACGAAACTCTTTCAGCAGTGTATTTTCGCGGTGTTTCTTCTGAGTTATTCTGTGCCCTCCTACG
GAAGATCAGTAGAGGGGATCAGCCGCAGACTCAAACGGGCCGTATCAGAGCACCAGCTACTGCATGACAAGGGCAAATC
AATCCAAGACTTACGAAGAAGGATATTCCTTCAAAATTTAATTGAAGGTGTCAACACTGCAGAAATCCGTGCAACTTCA
GAGGTCTCACCTAACCCTAAGCCTGCTACCAACACAAAGAACTACCCTGTCCGTTTTGGCAGTGAAGATGAGGGCAGAT
ACCTAACTCAGGAGACAAACAAATCACAGACCTACAAGGAACAGCCCCTGAAGGTATCAGGGAAGAAAAAGAAAGCAAA
GCCTGGAAAACGTAAAGAACAAGAGAAGAAAAAGAGGCGAGCTCGCTCAGCTTGGCTAAATTCTGGCATGTATGGAAGC
AATGTAACTGAGAGCCCAGTCTTGGACAACTCTGTTACTACACATAATCATATTTTAAGGAGGCGCTGATATTTTCAGC
AAGACAACTTTGGAAGACATATTGCAGTATTCTGTAATAGTGAACATAGAACATATGGGAAGTATTAAAATATTTATTA
CCTGTAAATATTGTAAATGCTCAGAATAAAACCTTTTTGCCCCATTGC
CitationZou H, Wieser R, Massagué J, Niswander L. Distinct roles of type I bone morphogenetic protein receptors in the formation and differentiation of cartilage. Genes Dev 1997 Sep 1;11(17):2191-203.
CopyrightCopyright © 1997, Cold Spring Harbor Laboratory Press
CommentsThe sequence below was obtained from NCBI (acc # NM_001174106.1 ) using the information provided in the publication as described in Schermer et al. 1991.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
25-30
stage 30
Leg
tarsal region
31-34
stage 34
Wing
carpal region

Entry 3

GEISHA IdPTHRP.Zhang.2003Data SourcePublication
Complete cDNA Template Probeshow
ACTAGCGTACAATTAACATCATTAGGAATCAGCCCTCCAGCTAACAGAGGAACTGCGACGAACAACGGTTTAAGCCCCG
GAGGATATGATGTTCACGAAACTCTTTCAGCAGTGTATTTTCGCGGTGTTTCTTCTGAGTTATTCTGTGCCCTCCTACG
GAAGATCAGTAGAGGGGATCAGCCGCAGACTCAAACGGGCCGTATCAGAGCACCAGCTACTGCATGACAAGGGCAAATC
AATCCAAGACTTACGAAGAAGGATATTCCTTCAAAATTTAATTGAAGGTGTCAACACTGCAGAAATCCGTGCAACTTCA
GAGGTCTCACCTAACCCTAAGCCTGCTACCAACACAAAGAACTACCCTGTCCGTTTTGGCAGTGAAGATGAGGGCAGAT
ACCTAACTCAGGAGACAAACAAATCACAGACCTACAAGGAACAGCCCCTGAAGGTATCAGGGAAGAAAAAGAAAGCAAA
GCCTGGAAAACGTAAAGAACAAGAGAAGAAAAAGAGGCGAGCTCGCTCAGCTTGGCTAAATTCTGGCATGTATGGAAGC
AATGTAACTGAGAGCCCAGTCTTGGACAACTCTGTTACTACACATAATCATATTTTAAGGAGGCGCTGATATTTTCAGC
AAGACAACTTTGGAAGACATATTGCAGTATTCTGTAATAGTGAACATAGAACATATGGGAAGTATTAAAATATTTATTA
CCTGTAAATATTGTAAATGCTCAGAATAAAACCTTTTTGCCCCATTGC
CitationZhang D, Schwarz EM, Rosier RN, Zuscik MJ, Puzas JE, O'Keefe RJ.ALK2 functions as a BMP type I receptor and induces Indian hedgehog in chondrocytes during skeletal development. J Bone Miner Res. 2003 Sep; 18(9):1593-604
CopyrightCopyright © 1999 - 2018 John Wiley & Sons, Inc.
CommentsInsufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (Acc. # NM_001174106.1).
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
19-23
stage 23
Wing
 

Entry 4

GEISHA IdPTHRP.Singh.2016Data SourcePublication
Complete cDNA Template Probeshow
ACTAGCGTACAATTAACATCATTAGGAATCAGCCCTCCAGCTAACAGAGGAACTGCGACGAACAACGGTTTAAGCCCCG
GAGGATATGATGTTCACGAAACTCTTTCAGCAGTGTATTTTCGCGGTGTTTCTTCTGAGTTATTCTGTGCCCTCCTACG
GAAGATCAGTAGAGGGGATCAGCCGCAGACTCAAACGGGCCGTATCAGAGCACCAGCTACTGCATGACAAGGGCAAATC
AATCCAAGACTTACGAAGAAGGATATTCCTTCAAAATTTAATTGAAGGTGTCAACACTGCAGAAATCCGTGCAACTTCA
GAGGTCTCACCTAACCCTAAGCCTGCTACCAACACAAAGAACTACCCTGTCCGTTTTGGCAGTGAAGATGAGGGCAGAT
ACCTAACTCAGGAGACAAACAAATCACAGACCTACAAGGAACAGCCCCTGAAGGTATCAGGGAAGAAAAAGAAAGCAAA
GCCTGGAAAACGTAAAGAACAAGAGAAGAAAAAGAGGCGAGCTCGCTCAGCTTGGCTAAATTCTGGCATGTATGGAAGC
AATGTAACTGAGAGCCCAGTCTTGGACAACTCTGTTACTACACATAATCATATTTTAAGGAGGCGCTGATATTTTCAGC
AAGACAACTTTGGAAGACATATTGCAGTATTCTGTAATAGTGAACATAGAACATATGGGAAGTATTAAAATATTTATTA
CCTGTAAATATTGTAAATGCTCAGAATAAAACCTTTTTGCCCCATTGC
CitationSingh PN, Ray A, Azad K, Bandyopadhyay A. A comprehensive mRNA expression analysis of developing chicken articular cartilage. Gene Expr Patterns. 2016 Jan;20(1):22-31.
CopyrightCopyright © 2015 Elsevier B.V. All rights reserved.
CommentsInsufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_001174106). Pthrp is also known as PTHLH in NCBI.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
25-30
stage 28
Limb Buds
 
31-38
stage 31
stage 34
stage 36
stage 38
Limb Buds
 
all
 
  
 Data from NCBI Unigene EST Profile
Unigene ID: Gga.2626

Mouse

Emage
EurexpressMGI:97800
MGI GXDMGI:97800

Frog

Xenbase959053

Fruit Fly

BDGP

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-050119-9, ZDB-GENE-110411-206
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