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BCL2
BCL2, apoptosis regulator| Gene | | Official Symbol | BCL2 | | Official Full Name | BCL2, apoptosis regulator | | CGNC ID | 9759 | | also known as | BCL-2, PCKBCL2, apoptosis regulator Bcl-2|B-cell CLL/lymphoma 2 | | gene type | protein-coding |
| | Genomic Map | | | Sequence Information | | | Gene Expression | | | Orthology | | | Gene Ontology | | Molecular Function | BH3 domain binding, channel activity, channel inhibitor activity, protease binding, more...protein heterodimerization activity, protein homodimerization activity, protein phosphatase 2A binding, sequence-specific DNA binding, transcription factor binding, ubiquitin protein ligase binding | | Biological Process | actin filament organization, axonogenesis, axon regeneration, B cell homeostasis, B cell lineage commitment, more...B cell proliferation, B cell receptor signaling pathway, behavioral fear response, branching involved in ureteric bud morphogenesis, CD8-positive, alpha-beta T cell lineage commitment, cell aging, cell-cell adhesion, cell growth, cellular response to glucose starvation, cellular response to hypoxia, cellular response to organic substance, cochlear nucleus development, defense response to virus, developmental growth, digestive tract morphogenesis, ear development, endoplasmic reticulum calcium ion homeostasis, extrinsic apoptotic signaling pathway in absence of ligand, extrinsic apoptotic signaling pathway via death domain receptors, focal adhesion assembly, gland morphogenesis, glomerulus development, hair follicle morphogenesis, homeostasis of number of cells within a tissue, intrinsic apoptotic signaling pathway in response to DNA damage, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, intrinsic apoptotic signaling pathway in response to oxidative stress, lymphoid progenitor cell differentiation, male gonad development, melanin metabolic process, melanocyte differentiation, mesenchymal cell development, metanephros development, negative regulation of anoikis, negative regulation of apoptotic process, negative regulation of calcium ion transport into cytosol, negative regulation of cell growth, negative regulation of cell migration, negative regulation of cellular pH reduction, negative regulation of extrinsic apoptotic signaling pathway in absence of ligand, negative regulation of G1/S transition of mitotic cell cycle, negative regulation of intrinsic apoptotic signaling pathway, negative regulation of mitotic cell cycle, negative regulation of myeloid cell apoptotic process, negative regulation of neuron apoptotic process, negative regulation of ossification, negative regulation of osteoblast proliferation, negative regulation of retinal cell programmed cell death, neuron apoptotic process, oocyte development, organ growth, ossification, ovarian follicle development, peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation, pigment granule organization, positive regulation of B cell proliferation, positive regulation of catalytic activity, positive regulation of cell growth, positive regulation of melanocyte differentiation, positive regulation of multicellular organism growth, positive regulation of neuron maturation, positive regulation of peptidyl-serine phosphorylation, positive regulation of skeletal muscle fiber development, positive regulation of smooth muscle cell migration, post-embryonic development, protein dephosphorylation, protein polyubiquitination, reactive oxygen species metabolic process, regulation of cell-matrix adhesion, regulation of glycoprotein biosynthetic process, regulation of mitochondrial membrane permeability, regulation of mitochondrial membrane potential, regulation of nitrogen utilization, regulation of protein heterodimerization activity, regulation of protein homodimerization activity, regulation of protein localization, regulation of protein stability, regulation of transmembrane transporter activity, regulation of viral genome replication, release of cytochrome c from mitochondria, renal system process, response to acid, response to cytokine, response to drug, response to gamma radiation, response to glucocorticoid, response to hydrogen peroxide, response to iron ion, response to ischemia, response to nicotine, response to toxic substance, response to UV-B, spleen development, T cell differentiation in thymus, T cell homeostasis, thymus development | | Cellular Component | cytosol, endoplasmic reticulum membrane, mitochondrial outer membrane, mitochondrion, myelin sheath, more...nuclear membrane, pore complex |
| | Links to other databases | |
No expression data available.
| | Data from NCBI Unigene EST Profile
Unigene ID: Gga.42172 |
MouseFrogFruit FlyZebra FinchZebrafish |
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