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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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BMPR1A
bone morphogenetic protein receptor type 1A

The human orthologue of this gene is associated
with the following human diseases:

Gene

Official Symbol	BMPR1A
Official Full Name	bone morphogenetic protein receptor type 1A
CGNC ID	1421
also known as	ALK-3, BMPR-1, BRK-1, bone morphogenetic protein receptor type-1A\|BMP receptor 1\|bone morphogenetic protein receptor, type IA\|bone morphogenic protein receptor 1\|protein kinase, bone morphogenetic protein receptor, type IA, BMPR1A
gene type	protein-coding

Genomic Map

	Ensembl
	NCBI
	UCSC
	Gallus-Browse

Sequence Information

Genomic
RNA	NM_205357
Polypeptide	NP_990688
Sequence Clusters/ESTs	Unigene

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.755

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly	33753			FBgn0003716
Human	657		MIM:612242	MIM:601299
Mouse	12166	ENSMUSG00000021796	All phenotypic alleles (7):Targeted, knock-out(2) Targeted, other(4) Gene trapped(1)	MGI:1338938
Xenopus	734017, 397712			485615
Zebrafish	58145, 447846	ENSDARG00000019728, ENSDARG00000045097	ZDB-GENE-000502-1, ZDB-GENE-040912-150	ZFIN:ZDB-GENE-000502-1, ZFIN:ZDB-GENE-040912-150

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Links to other databases

Entrez Gene	396308
Ensembl Gene	ENSGALG00000002003
KEGG	gga:396308

Entry 1

GEISHA Id	BMPR1A.UApcr	Data Source	GEISHA ISH Analysis
Forward cDNA Template Primer	AGGAAATGGGGTAACGCTCG
Reverse cDNA Template Primer	ATTAACCCTCACTAAAGGCAGAGTATGCCAGTTTGAGGAG	cDNA Template Length	886
Forward cDNA Template Probe	show AGTGCTACTGCTCAGGACATTGTCCAGATGATGCTATTAATAACACATGCATAACTAATGGGCATTGCTTTGCTATCAT TGAGGAAGATGAACATGGGGAACCAACACTTGCTTCTGGCTGCATGAAGTATGAAGGTTCAGACTTCCAGTGCAAGGAT TCACCAAAAGCACAATTACGTCGGACAATTGAGTGCTGTCGGACTGATTTCTGCAATCAGGATTTACAGCCGACATTAC CACCGCTTGATAGTACAGATGGACTTTTTGATGGCAGCATTCGTTGGATGGCAGTCTTAATTTCTATGGCAGTCTGCAT AATTGTTATGATCATCTTATTTAGCTGCTTTTGTTACAAGCATTATTGTAAGTCAATGGCAAAGAGACACTGTTATAAT CGTGACCTGGAACAAGATGAAGCATTCATTCCAGCTGGGGAGTCGTTAAAAGACCTCATTGACCAGTCGCAAAGTTCTG GCAGTGGCTCAGGGCTACCATTGCTGGTTCAGCGCACGATTGCCAAACAAATTCAGATGGTGAGGCAAGTTGGAAAGGG ACGATATGGTGAAGTGTGGATGGGCAAATGGAGAGGTGAAAAAGTTGCAGTCAAATTGTTTTTCACCACAGAAGAAGCC AGCTGGTTCCGAGAAACAGAGATTTACCAAACTGTTTTAATGCGTCATGAAAACATCCTTGGTTTTATAGCTGCAGATA TTAAAGGCACTGGATCCTGGACACAGCTTTACTTGATTACAGATTATCATGAAAATGGATCACTATATGATTTTCTGAA GTGCACTACACTAGACAACAGGGCTCTCCTCAAACTGGCATACTCTGCTGCATG

Stage

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7-12

stage 7

stage 9

stage 10

stage 11

Anterior Intestinal Portal
Eye
Forebrain
Head Mesenchyme
Heart
Hindbrain
Intermediate Mesoderm
Lateral Plate Mesoderm
Midbrain
Neural Plate/Tube
Notochord
Somites
Unlabeled

13-18

stage 17

Eye
Head Mesenchyme
Pharyngeal Arches and Clefts
Somites
Spinal Cord

19-21

stage 20

stage 21

Ear/Otic Placode
Eye
Gut
Head Mesenchyme
Limb Buds
Midgut
Pharyngeal Arches and Clefts
Somites

Entry 2

GEISHA Id	BMPR-1A.McPherson.2000	Data Source	Publication
Complete cDNA Template Probe	show ATGACTCGACTGAGAGTCTGTGAGCGATTGCTTGGAGCCTACCTGCTTCTCATTCTCCATGTTCAAGGACAAAATCTAG ACAGCATGCTCCATGGCACGGGAATGAAGACAAATCCTGACCAAAAGAAACAAGCCAATGGGGTAACGCTCGCTCCAGA AGACACCTTACCATTTCTTAAGTGCTACTGCTCAGGACATTGTCCAGATGATGCTATTAACAACACATGCATAACTAAT GGGCATTGCTTTGCTATCATTGAGGAAGATGAACATGGGGAACCAACACTTGCTTCTGGCTGCATGAAGTATGAAGGTT CAGACTTCCAGTGCAAGGATTCACCAAAAGCACAATTACGTCGGACAATTGAGTGCTGTCGGACTGACTTCTGCAATCA GGATTTACAGCCAACATTACCAACGCTTGATAGTACAGATGGGCTTTTTGATGGCAGCATTCGTTGGATGGCAGTCTTA ATTTCTATGGCAGTCTGCATAATTGTCATGGTCATCTTATTTAGCTGCTTTTGTTACAAGCACTATTGTAAGTCAATGG CAAAGAGACACTGTTATAATCGTGACCTGGAACAAGATGAAGCATTTATTCCAGCTGGGGAGTCATTAAAGGACCTCAT TGACCAGTCACAGAGTTCAGGCAGCGGCTCAGGACTACCATTGCTGGTTCAGCGCACGATTGCCAAACAAATTCAGATG GTGAGGCAAGTTGGAAAGGGAAGATATGGTGAAGTGTGGATGGGGAAATGGAGGGGTGAAAAAGTCGCAGTCAAAGTGT TTTTCACCACAGAAGAAGCCAGTTGGTTCCGAGAAACAGAGATTTACCAAACTGTTCTAATGCGTCATGAAAACATCCT TGGTTTTATAGCTGCAGATATTAAAGGCACTGGATCCTGGACACAGCTTTACTTGATTACAGATTATCATGAAAATGGA TCTCTATATGATTTTCTGAAGTGCACTACTCTAGATAACAGGGCGCTCCTCAAACTGGCATACTCTGCTGCATGTGGTC TGTGCCATCTACACACGGAAATCTATGGGACGCAAGGCAAGCCTGCTATTGCACACAGGGACCTGAAAAGTAAAAACAT TTTGATAAAGAAGAATGGGACGTGCTGTATTGCTGACTTGGGGCTCGCAGTGAAGTTTAACAGTGACACAAATGAAGTT GATGTTCCTTTGAATACCAGAGTGGGAACAAAACGTTACATGGCTCCAGAGGTCCTAGATGAAAGCCTGAATAAAAACC ATTTTCAACCATACATCATGGCTGACATATACAGTTTTGGGCTGATAATTTGGGAAATGGCTCGACGCTGTGTCGCAGG AGGTATTGTTGAAGAGTATCAGTTGCCATACTATGACATGGTGCCAAATGATCCATCTTATGAGGACATGAGGGAAGTG GTGTGTGTCAAACGTCTGCGCCCAGTAGTATCTAACAGATGGAATAGTGATGAATGTTTAAGAGCAATATTAAAATTAA TGTCTGAATGCTGGGCTCACAATCCTGCTTCAAGACTCACTGCCTTGAGGATCAAGAAGACACTTGCCAAGATGGTGGA ATCACAAGATGTAAAGATTTGA
Citation	McPherson CE, Varley JE, Maxwell GD. Expression and regulation of type I BMP receptors during early avian sympathetic ganglion development. Dev Biol. 2000 May 1;221(1):220-32.
Copyright	Reprinted with permission from Elsevier. Copyright © 2000 Elsevier B.V. All rights reserved.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (AF189777). Thus probe shown is from quail, but it is mapped to its homolog in chick.

Stage

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13-18

stage 16

stage 17

stage 18

Aorta
Dermomyotome
Spinal Ganglia and Nerves

Dorsal Aorta
Figure 4 compares the expressions of Cash-1, BMP-4, BMPR-IA, and BMPR-IB mRNA in stage 16, 17, and 18 quail embryos.
Quail
Sympathetic Ganglia

19-23

stage 23

Aorta
Spinal Ganglia and Nerves

Dorsal Aorta
Figure 2 compares the expressions of BMP-4, BMPR-IA, BMPR-IB, and TH mRNAs in stage HH23 quail embryos.
Quail
Sympathetic Ganglia

Entry 3

GEISHA Id	BmprIA.Ashique.2002	Data Source	Publication
Complete cDNA Template Probe	show GGCGCGGCCTGCGTAGGCAACGGAGAGCGGCTTTCTCCTGCTTCGCCTTCTCTCCCTCCGCAAAGGATGAGGAGCCCCC AGGAGCGATTAATAGAAATATGCGTTTCCATAATACCACCTTTGAACTAATGAAGTGGAAGTACAGATGAAAACAGTCT GGAGGAAGCTTGAAGTACAGTATAGTTTCATTCAGTTTCTTAATTCAAAGTAAGGAAACGAAGTTGGAAGAGTTACAGA ATCATCCTTGCAGTCTTGTATTAGGCTTCACCAAACAGACTAAGCTTAACGATTGTCAAGCAGAAGGGCCACTTGCCTT GCACAGGAAGGATTAACAGTGAACAATGACTCGACTGAGAGTTTGTGAGCGATTGCTTGGAGCCTATCTGCTTATCATT CTCCATGTTCAAGGACAAAATCTAGACAGCATGCTCCATGGCACAGGAATGAAGACAAATCCTGACCAAAAGAAACAAG GAAATGGGGTAACGCTCGCTCCAGAGGACACCTTACCATTCCTTAAGTGCTACTGCTCAGGACATTGTCCAGATGATGC TATTAATAACACATGCATAACTAATGGGCATTGCTTTGCTATCATTGAGGAAGATGAACATGGGGAACCAACACTTGCT TCTGGCTGCATGAAGTATGAAGGTTCAGACTTCCAGTGCAAGGATTCACCAAAAGCACAATTACGTCGGACAATTGAGT GCTGTCGGACTGATTTCTGCAATCAGGATTTACAGCCGACATTACCACCGCTTGATAGTACAGATGGACTTTTTGATGG CAGCATTCGTTGGATGGCAGTCTTAATTTCTATGGCAGTCTGCATAATTGTTATGATCATCTTATTTAGCTGCTTTTGT TACAAGCATTATTGTAAGTCAATGGCAAAGAGACACTGTTATAATCGTGACCTGGAACAAGATGAAGCATTCATTCCAG CTGGGGAGTCGTTAAAAGACCTCATTGACCAGTCGCAAAGTTCTGGCAGTGGCTCAGGGCTACCATTGCTGGTTCAGCG CACGATTGCCAAACAAATTCAGATGGTGAGGCAAGTTGGAAAGGGACGATATGGTGAAGTGTGGATGGGCAAATGGAGA GGTGAAAAAGTTGCAGTCAAATTGTTTTTCACCACAGAAGAAGCCAGCTGGTTCCGAGAAACAGAGATTTACCAAACTG TTTTAATGCGTCATGAAAACATCCTTGGTTTTATAGCTGCAGATATTAAAGGCACTGGATCCTGGACACAGCTTTACTT GATTACAGATTATCATGAAAATGGATCACTATATGATTTTCTGAAGTGCACTACACTAGACAACAGGGCTCTCCTCAAA CTGGCATACTCTGCTGCATGTGGTCTGTGCCATTTACACACAGAAATCTATGGGACGCAAGGCAAGCCTGCTATAGCAC ACAGGGACCTGAAAAGTAAAAACATTTTGATAAAGAAGAATGGGACATGCTGTATTGCTGACTTGGGTCTCGCAGTCAA GTTTAACAGTGATACAAATGAAGTTGATGTTCCCTTGAATACTAGAGTGGGAACAAAACGTTACATGGCTCCAGAGGTC CTTGATGAAAGCCTGAATAAAAACCATTTTCAACCATACATCATGGCTGACATATACAGTTTTGGGCTGATAATTTGGG AAATGGCTCGACGCTGTGTCACAGGAGGTATTGTTGAAGAGTACCAGTTGCCATACTATGACATGGTGCCAAATGATCC ATCTTATGAGGACATGAGAGAAGTGGTGTGTGTCAAACGTCTGCGCCCAGTAGTATCTAACAGATGGAATAGTGATGAA TGTTTAAGAGCAATATTAAAATTAATGTCTGAATGCTGGGCTCACAATCCTGCTTCAAGACTCACTGCCTTGAGGATCA AGAAGACGCTTGCCAAGATGGTGGAATCACAAGATGTAAAGATTTGACAAAGTAAATTGACATTAATTTTAAT
Citation	Ashique AM, Fu K, Richman JM. Signalling via type IA and type IB bone morphogenetic protein receptors (BMPR) regulates intramembranous bone formation, chondrogenesis and feather formation in the chicken embryo. Int J Dev Biol. 2002 Mar;46(2):243-53.
Copyright	"Reprinted from Int. J. Dev. Biol., 46, Ashique AM, Fu K, Richman JM, Signalling via type IA and type IB bone morphogenetic protein receptors (BMPR) regulates intramembranous bone formation, chondrogenesis and feather formation in the chicken embryo, 243-53, Copyright (2002), with permission from Copyright © 2002 UBC Press". All rights reserved.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc #NM_205357).

Stage

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25-30

stage 30

Face Mesenchyme
Surface Ectoderm

Egg tooth

31-44

stage 32

stage 44

Face Mesenchyme
Surface Ectoderm

Comparison with other genes
Egg tooth

Entry 4

GEISHA Id	BMPR-1A.Hyre.2003	Data Source	Publication
Complete cDNA Template Probe	show GGCGCGGCCTGCGTAGGCAACGGAGAGCGGCTTTCTCCTGCTTCGCCTTCTCTCCCTCCGCAAAGGATGAGGAGCCCCC AGGAGCGATTAATAGAAATATGCGTTTCCATAATACCACCTTTGAACTAATGAAGTGGAAGTACAGATGAAAACAGTCT GGAGGAAGCTTGAAGTACAGTATAGTTTCATTCAGTTTCTTAATTCAAAGTAAGGAAACGAAGTTGGAAGAGTTACAGA ATCATCCTTGCAGTCTTGTATTAGGCTTCACCAAACAGACTAAGCTTAACGATTGTCAAGCAGAAGGGCCACTTGCCTT GCACAGGAAGGATTAACAGTGAACAATGACTCGACTGAGAGTTTGTGAGCGATTGCTTGGAGCCTATCTGCTTATCATT CTCCATGTTCAAGGACAAAATCTAGACAGCATGCTCCATGGCACAGGAATGAAGACAAATCCTGACCAAAAGAAACAAG GAAATGGGGTAACGCTCGCTCCAGAGGACACCTTACCATTCCTTAAGTGCTACTGCTCAGGACATTGTCCAGATGATGC TATTAATAACACATGCATAACTAATGGGCATTGCTTTGCTATCATTGAGGAAGATGAACATGGGGAACCAACACTTGCT TCTGGCTGCATGAAGTATGAAGGTTCAGACTTCCAGTGCAAGGATTCACCAAAAGCACAATTACGTCGGACAATTGAGT GCTGTCGGACTGATTTCTGCAATCAGGATTTACAGCCGACATTACCACCGCTTGATAGTACAGATGGACTTTTTGATGG CAGCATTCGTTGGATGGCAGTCTTAATTTCTATGGCAGTCTGCATAATTGTTATGATCATCTTATTTAGCTGCTTTTGT TACAAGCATTATTGTAAGTCAATGGCAAAGAGACACTGTTATAATCGTGACCTGGAACAAGATGAAGCATTCATTCCAG CTGGGGAGTCGTTAAAAGACCTCATTGACCAGTCGCAAAGTTCTGGCAGTGGCTCAGGGCTACCATTGCTGGTTCAGCG CACGATTGCCAAACAAATTCAGATGGTGAGGCAAGTTGGAAAGGGACGATATGGTGAAGTGTGGATGGGCAAATGGAGA GGTGAAAAAGTTGCAGTCAAATTGTTTTTCACCACAGAAGAAGCCAGCTGGTTCCGAGAAACAGAGATTTACCAAACTG TTTTAATGCGTCATGAAAACATCCTTGGTTTTATAGCTGCAGATATTAAAGGCACTGGATCCTGGACACAGCTTTACTT GATTACAGATTATCATGAAAATGGATCACTATATGATTTTCTGAAGTGCACTACACTAGACAACAGGGCTCTCCTCAAA CTGGCATACTCTGCTGCATGTGGTCTGTGCCATTTACACACAGAAATCTATGGGACGCAAGGCAAGCCTGCTATAGCAC ACAGGGACCTGAAAAGTAAAAACATTTTGATAAAGAAGAATGGGACATGCTGTATTGCTGACTTGGGTCTCGCAGTCAA GTTTAACAGTGATACAAATGAAGTTGATGTTCCCTTGAATACTAGAGTGGGAACAAAACGTTACATGGCTCCAGAGGTC CTTGATGAAAGCCTGAATAAAAACCATTTTCAACCATACATCATGGCTGACATATACAGTTTTGGGCTGATAATTTGGG AAATGGCTCGACGCTGTGTCACAGGAGGTATTGTTGAAGAGTACCAGTTGCCATACTATGACATGGTGCCAAATGATCC ATCTTATGAGGACATGAGAGAAGTGGTGTGTGTCAAACGTCTGCGCCCAGTAGTATCTAACAGATGGAATAGTGATGAA TGTTTAAGAGCAATATTAAAATTAATGTCTGAATGCTGGGCTCACAATCCTGCTTCAAGACTCACTGCCTTGAGGATCA AGAAGACGCTTGCCAAGATGGTGGAATCACAAGATGTAAAGATTTGACAAAGTAAATTGACATTAATTTTAAT
Citation	Hyer J, Kuhlman J, Afif E, Mikawa T. Optic cup morphogenesis requires pre-lens ectoderm but not lens differentiation. Dev Biol. 2003 Jul 15;259(2):351-63.
Copyright	Copyright © 2003 Elsevier Science (USA) All rights reserved.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_205357).

Stage

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7-11

stage 11

Eye
Forebrain

Entry 5

GEISHA Id	BMPR1A.Huber.2008	Data Source	Publication
Complete cDNA Template Probe	show GGCGCGGCCTGCGTAGGCAACGGAGAGCGGCTTTCTCCTGCTTCGCCTTCTCTCCCTCCGCAAAGGATGAGGAGCCCCC AGGAGCGATTAATAGAAATATGCGTTTCCATAATACCACCTTTGAACTAATGAAGTGGAAGTACAGATGAAAACAGTCT GGAGGAAGCTTGAAGTACAGTATAGTTTCATTCAGTTTCTTAATTCAAAGTAAGGAAACGAAGTTGGAAGAGTTACAGA ATCATCCTTGCAGTCTTGTATTAGGCTTCACCAAACAGACTAAGCTTAACGATTGTCAAGCAGAAGGGCCACTTGCCTT GCACAGGAAGGATTAACAGTGAACAATGACTCGACTGAGAGTTTGTGAGCGATTGCTTGGAGCCTATCTGCTTATCATT CTCCATGTTCAAGGACAAAATCTAGACAGCATGCTCCATGGCACAGGAATGAAGACAAATCCTGACCAAAAGAAACAAG GAAATGGGGTAACGCTCGCTCCAGAGGACACCTTACCATTCCTTAAGTGCTACTGCTCAGGACATTGTCCAGATGATGC TATTAATAACACATGCATAACTAATGGGCATTGCTTTGCTATCATTGAGGAAGATGAACATGGGGAACCAACACTTGCT TCTGGCTGCATGAAGTATGAAGGTTCAGACTTCCAGTGCAAGGATTCACCAAAAGCACAATTACGTCGGACAATTGAGT GCTGTCGGACTGATTTCTGCAATCAGGATTTACAGCCGACATTACCACCGCTTGATAGTACAGATGGACTTTTTGATGG CAGCATTCGTTGGATGGCAGTCTTAATTTCTATGGCAGTCTGCATAATTGTTATGATCATCTTATTTAGCTGCTTTTGT TACAAGCATTATTGTAAGTCAATGGCAAAGAGACACTGTTATAATCGTGACCTGGAACAAGATGAAGCATTCATTCCAG CTGGGGAGTCGTTAAAAGACCTCATTGACCAGTCGCAAAGTTCTGGCAGTGGCTCAGGGCTACCATTGCTGGTTCAGCG CACGATTGCCAAACAAATTCAGATGGTGAGGCAAGTTGGAAAGGGACGATATGGTGAAGTGTGGATGGGCAAATGGAGA GGTGAAAAAGTTGCAGTCAAATTGTTTTTCACCACAGAAGAAGCCAGCTGGTTCCGAGAAACAGAGATTTACCAAACTG TTTTAATGCGTCATGAAAACATCCTTGGTTTTATAGCTGCAGATATTAAAGGCACTGGATCCTGGACACAGCTTTACTT GATTACAGATTATCATGAAAATGGATCACTATATGATTTTCTGAAGTGCACTACACTAGACAACAGGGCTCTCCTCAAA CTGGCATACTCTGCTGCATGTGGTCTGTGCCATTTACACACAGAAATCTATGGGACGCAAGGCAAGCCTGCTATAGCAC ACAGGGACCTGAAAAGTAAAAACATTTTGATAAAGAAGAATGGGACATGCTGTATTGCTGACTTGGGTCTCGCAGTCAA GTTTAACAGTGATACAAATGAAGTTGATGTTCCCTTGAATACTAGAGTGGGAACAAAACGTTACATGGCTCCAGAGGTC CTTGATGAAAGCCTGAATAAAAACCATTTTCAACCATACATCATGGCTGACATATACAGTTTTGGGCTGATAATTTGGG AAATGGCTCGACGCTGTGTCACAGGAGGTATTGTTGAAGAGTACCAGTTGCCATACTATGACATGGTGCCAAATGATCC ATCTTATGAGGACATGAGAGAAGTGGTGTGTGTCAAACGTCTGCGCCCAGTAGTATCTAACAGATGGAATAGTGATGAA TGTTTAAGAGCAATATTAAAATTAATGTCTGAATGCTGGGCTCACAATCCTGCTTCAAGACTCACTGCCTTGAGGATCA AGAAGACGCTTGCCAAGATGGTGGAATCACAAGATGTAAAGATTTGACAAAGTAAATTGACATTAATTTTAAT
Citation	Huber K, Franke A, Brühl B, Krispin S, Ernsberger U, Schober A, von Bohlen und Halbach O, Rohrer H, Kalcheim C, Unsicker K. Persistent expression of BMP-4 in embryonic chick adrenal cortical cells and its role in chromaffin cell development. Neural Dev. 2008 Oct 22;3:28.
Copyright	© 2008 Huber et al; licensee BioMed Central Ltd. (requested from Dr. Unsicker)

Stage

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stage 31

Intermediate Mesoderm

Adrenal Gland

Entry 6

GEISHA Id	BMPR1A.Ishii.2010	Data Source	Publication
Complete cDNA Template Probe	show GGCGCGGCCTGCGTAGGCAACGGAGAGCGGCTTTCTCCTGCTTCGCCTTCTCTCCCTCCGCAAAGGATGAGGAGCCCCC AGGAGCGATTAATAGAAATATGCGTTTCCATAATACCACCTTTGAACTAATGAAGTGGAAGTACAGATGAAAACAGTCT GGAGGAAGCTTGAAGTACAGTATAGTTTCATTCAGTTTCTTAATTCAAAGTAAGGAAACGAAGTTGGAAGAGTTACAGA ATCATCCTTGCAGTCTTGTATTAGGCTTCACCAAACAGACTAAGCTTAACGATTGTCAAGCAGAAGGGCCACTTGCCTT GCACAGGAAGGATTAACAGTGAACAATGACTCGACTGAGAGTTTGTGAGCGATTGCTTGGAGCCTATCTGCTTATCATT CTCCATGTTCAAGGACAAAATCTAGACAGCATGCTCCATGGCACAGGAATGAAGACAAATCCTGACCAAAAGAAACAAG GAAATGGGGTAACGCTCGCTCCAGAGGACACCTTACCATTCCTTAAGTGCTACTGCTCAGGACATTGTCCAGATGATGC TATTAATAACACATGCATAACTAATGGGCATTGCTTTGCTATCATTGAGGAAGATGAACATGGGGAACCAACACTTGCT TCTGGCTGCATGAAGTATGAAGGTTCAGACTTCCAGTGCAAGGATTCACCAAAAGCACAATTACGTCGGACAATTGAGT GCTGTCGGACTGATTTCTGCAATCAGGATTTACAGCCGACATTACCACCGCTTGATAGTACAGATGGACTTTTTGATGG CAGCATTCGTTGGATGGCAGTCTTAATTTCTATGGCAGTCTGCATAATTGTTATGATCATCTTATTTAGCTGCTTTTGT TACAAGCATTATTGTAAGTCAATGGCAAAGAGACACTGTTATAATCGTGACCTGGAACAAGATGAAGCATTCATTCCAG CTGGGGAGTCGTTAAAAGACCTCATTGACCAGTCGCAAAGTTCTGGCAGTGGCTCAGGGCTACCATTGCTGGTTCAGCG CACGATTGCCAAACAAATTCAGATGGTGAGGCAAGTTGGAAAGGGACGATATGGTGAAGTGTGGATGGGCAAATGGAGA GGTGAAAAAGTTGCAGTCAAATTGTTTTTCACCACAGAAGAAGCCAGCTGGTTCCGAGAAACAGAGATTTACCAAACTG TTTTAATGCGTCATGAAAACATCCTTGGTTTTATAGCTGCAGATATTAAAGGCACTGGATCCTGGACACAGCTTTACTT GATTACAGATTATCATGAAAATGGATCACTATATGATTTTCTGAAGTGCACTACACTAGACAACAGGGCTCTCCTCAAA CTGGCATACTCTGCTGCATGTGGTCTGTGCCATTTACACACAGAAATCTATGGGACGCAAGGCAAGCCTGCTATAGCAC ACAGGGACCTGAAAAGTAAAAACATTTTGATAAAGAAGAATGGGACATGCTGTATTGCTGACTTGGGTCTCGCAGTCAA GTTTAACAGTGATACAAATGAAGTTGATGTTCCCTTGAATACTAGAGTGGGAACAAAACGTTACATGGCTCCAGAGGTC CTTGATGAAAGCCTGAATAAAAACCATTTTCAACCATACATCATGGCTGACATATACAGTTTTGGGCTGATAATTTGGG AAATGGCTCGACGCTGTGTCACAGGAGGTATTGTTGAAGAGTACCAGTTGCCATACTATGACATGGTGCCAAATGATCC ATCTTATGAGGACATGAGAGAAGTGGTGTGTGTCAAACGTCTGCGCCCAGTAGTATCTAACAGATGGAATAGTGATGAA TGTTTAAGAGCAATATTAAAATTAATGTCTGAATGCTGGGCTCACAATCCTGCTTCAAGACTCACTGCCTTGAGGATCA AGAAGACGCTTGCCAAGATGGTGGAATCACAAGATGTAAAGATTTGACAAAGTAAATTGACATTAATTTTAAT
Citation	Ishii Y, Garriock RJ, Navetta AM, Coughlin LE, Mikawa T.. BMP Signals Promote Proepicardial Protrusion Necessary for Recruitment of Coronary Vessel and Epicardial Progenitors to the Heart. Dev Cell. 2010 August 17; 19(2): 307316.
Copyright	Copyright © 2010 Elsevier Inc. All rights reserved.

Stage

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13-16

stage 16

Proepicardium

Entry 7

GEISHA Id	BMPR-1A.Zou.1997	Data Source	GEISHA ISH Analysis
Complete cDNA Template Probe	show GGCGCGGCCTGCGTAGGCAACGGAGAGCGGCTTTCTCCTGCTTCGCCTTCTCTCCCTCCGCAAAGGATGAGGAGCCCCC AGGAGCGATTAATAGAAATATGCGTTTCCATAATACCACCTTTGAACTAATGAAGTGGAAGTACAGATGAAAACAGTCT GGAGGAAGCTTGAAGTACAGTATAGTTTCATTCAGTTTCTTAATTCAAAGTAAGGAAACGAAGTTGGAAGAGTTACAGA ATCATCCTTGCAGTCTTGTATTAGGCTTCACCAAACAGACTAAGCTTAACGATTGTCAAGCAGAAGGGCCACTTGCCTT GCACAGGAAGGATTAACAGTGAACAATGACTCGACTGAGAGTTTGTGAGCGATTGCTTGGAGCCTATCTGCTTATCATT CTCCATGTTCAAGGACAAAATCTAGACAGCATGCTCCATGGCACAGGAATGAAGACAAATCCTGACCAAAAGAAACAAG GAAATGGGGTAACGCTCGCTCCAGAGGACACCTTACCATTCCTTAAGTGCTACTGCTCAGGACATTGTCCAGATGATGC TATTAATAACACATGCATAACTAATGGGCATTGCTTTGCTATCATTGAGGAAGATGAACATGGGGAACCAACACTTGCT TCTGGCTGCATGAAGTATGAAGGTTCAGACTTCCAGTGCAAGGATTCACCAAAAGCACAATTACGTCGGACAATTGAGT GCTGTCGGACTGATTTCTGCAATCAGGATTTACAGCCGACATTACCACCGCTTGATAGTACAGATGGACTTTTTGATGG CAGCATTCGTTGGATGGCAGTCTTAATTTCTATGGCAGTCTGCATAATTGTTATGATCATCTTATTTAGCTGCTTTTGT TACAAGCATTATTGTAAGTCAATGGCAAAGAGACACTGTTATAATCGTGACCTGGAACAAGATGAAGCATTCATTCCAG CTGGGGAGTCGTTAAAAGACCTCATTGACCAGTCGCAAAGTTCTGGCAGTGGCTCAGGGCTACCATTGCTGGTTCAGCG CACGATTGCCAAACAAATTCAGATGGTGAGGCAAGTTGGAAAGGGACGATATGGTGAAGTGTGGATGGGCAAATGGAGA GGTGAAAAAGTTGCAGTCAAATTGTTTTTCACCACAGAAGAAGCCAGCTGGTTCCGAGAAACAGAGATTTACCAAACTG TTTTAATGCGTCATGAAAACATCCTTGGTTTTATAGCTGCAGATATTAAAGGCACTGGATCCTGGACACAGCTTTACTT GATTACAGATTATCATGAAAATGGATCACTATATGATTTTCTGAAGTGCACTACACTAGACAACAGGGCTCTCCTCAAA CTGGCATACTCTGCTGCATGTGGTCTGTGCCATTTACACACAGAAATCTATGGGACGCAAGGCAAGCCTGCTATAGCAC ACAGGGACCTGAAAAGTAAAAACATTTTGATAAAGAAGAATGGGACATGCTGTATTGCTGACTTGGGTCTCGCAGTCAA GTTTAACAGTGATACAAATGAAGTTGATGTTCCCTTGAATACTAGAGTGGGAACAAAACGTTACATGGCTCCAGAGGTC CTTGATGAAAGCCTGAATAAAAACCATTTTCAACCATACATCATGGCTGACATATACAGTTTTGGGCTGATAATTTGGG AAATGGCTCGACGCTGTGTCACAGGAGGTATTGTTGAAGAGTACCAGTTGCCATACTATGACATGGTGCCAAATGATCC ATCTTATGAGGACATGAGAGAAGTGGTGTGTGTCAAACGTCTGCGCCCAGTAGTATCTAACAGATGGAATAGTGATGAA TGTTTAAGAGCAATATTAAAATTAATGTCTGAATGCTGGGCTCACAATCCTGCTTCAAGACTCACTGCCTTGAGGATCA AGAAGACGCTTGCCAAGATGGTGGAATCACAAGATGTAAAGATTTGACAAAGTAAATTGACATTAATTTTAAT
Citation	Zou H, Wieser R, Massagué J, Niswander L. Distinct roles of type I bone morphogenetic protein receptors in the formation and differentiation of cartilage. Genes Dev 1997 Sep 1;11(17):2191-203.
Copyright	Copyright © 1997, Cold Spring Harbor Laboratory Press
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (Acc. # NM_205357.1).

Stage

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Location (click to highlight)

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25-30

stage 30

Wing Mesenchyme

31-41

stage 32

stage 34

stage 41

Leg
Wing

carpal region
tibia
ulna

Entry 8

GEISHA Id	BRK‐1.Belecky-Adams.2001	Data Source	Publication
Complete cDNA Template Probe	show AAGCTTAACGATTGTCAAGCAGAAGGGCCACTTGCCTTGCACAGGAAGGATTAACAGTGAACAATGACTCGACTGAGAG TTTGTGAGCGATTGCTTGGAGCCTATCTGCTTATCATTCTCCATGTTCAAGGACAAAATCTAGACAGCATGCTCCATGG CACAGGAATGAAGACAAATCCTGACCAAAAGAAACAAGGAAATGGGGTAACGCTCGCTCCAGAGGACACCTTACCATTC CTTAAGTGCTACTGCTCAGGACATTGTCCAGATGATGCTATTAATAACACATGCATAACTAATGGGCATTGCTTTGCTA TCATTGAGGAAGATGAACATGGGGAACCAACACTTGCTTCTGGCTGCATGAAGTATGAAGGTTCAGACTTCCAGTGCAA GGATTCACCAAAAGCACAATTACGTCGGACAATTGAGTGCTGTCGGACTGATTTCTGCAATCAGGATTTACAGCCGACA TTACCACCGCTTGATAGTACAGATGGACTTTTTGATGGCAGCATTCGTTGGATGGCAGTCTTAATTTCTATGGCAGTCT GCATAATTGTTATGATCATCTTATTTAGCTGCTTTTGTTACAAGCATTATTGTAAGTCAATGGCAAAGAGACACTGTTA TAATCGTGACCTGGAACAAGATGAAGCATTCATTCCAGCTGGGGAGTCGTTAAAAGACCTCATTGACCAGTCGCAAAGT TCTGGCAGTGGCTCAGGGCTACCATTGCTGGTTCAGCGCACGATTGCCAAACAAATTCAGATGGTGAGGCAAGTTGGAA AGGGACGATATGGTGAAGTGTGGATGGGCAAATGGAGAGGTGAAAAAGTTGCAGTCAAATTGTTTTTCACCACAGAAGA AGCCAGCTGGTTCCGAGAAACAGAGATTTACCAAACTGTTTTAATGCGTCATGAAAACATCCTTGGTTTTATAGCTGCA GATATTAAAGGCACTGGATCC
Citation	Belecky-Adams T, Adler R. Developmental expression patterns of bone morphogenetic proteins, receptors, and binding proteins in the chick retina. J Comp Neurol. 2001 Feb 19;430(4):562-72.
Copyright	Copyright © 2001 Wiley‐Liss, Inc.
Comments	The complete cDNA template sequence was obtained from the information from the publication as described in Belecky-Adams et al. 2001. BRK-1 is also known as BMPR1A in NCBI.

Stage

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13-18

stage 18

Eye

31-44

stage 34

stage 44

Retina

Entry 9

GEISHA Id	BMPR1A.Sela-Donenfeld.2002	Data Source	Publication
Complete cDNA Template Probe	show GGCGCGGCCTGCGTAGGCAACGGAGAGCGGCTTTCTCCTGCTTCGCCTTCTCTCCCTCCGCAAAGGATGAGGAGCCCCC AGGAGCGATTAATAGAAATATGCGTTTCCATAATACCACCTTTGAACTAATGAAGTGGAAGTACAGATGAAAACAGTCT GGAGGAAGCTTGAAGTACAGTATAGTTTCATTCAGTTTCTTAATTCAAAGTAAGGAAACGAAGTTGGAAGAGTTACAGA ATCATCCTTGCAGTCTTGTATTAGGCTTCACCAAACAGACTAAGCTTAACGATTGTCAAGCAGAAGGGCCACTTGCCTT GCACAGGAAGGATTAACAGTGAACAATGACTCGACTGAGAGTTTGTGAGCGATTGCTTGGAGCCTATCTGCTTATCATT CTCCATGTTCAAGGACAAAATCTAGACAGCATGCTCCATGGCACAGGAATGAAGACAAATCCTGACCAAAAGAAACAAG GAAATGGGGTAACGCTCGCTCCAGAGGACACCTTACCATTCCTTAAGTGCTACTGCTCAGGACATTGTCCAGATGATGC TATTAATAACACATGCATAACTAATGGGCATTGCTTTGCTATCATTGAGGAAGATGAACATGGGGAACCAACACTTGCT TCTGGCTGCATGAAGTATGAAGGTTCAGACTTCCAGTGCAAGGATTCACCAAAAGCACAATTACGTCGGACAATTGAGT GCTGTCGGACTGATTTCTGCAATCAGGATTTACAGCCGACATTACCACCGCTTGATAGTACAGATGGACTTTTTGATGG CAGCATTCGTTGGATGGCAGTCTTAATTTCTATGGCAGTCTGCATAATTGTTATGATCATCTTATTTAGCTGCTTTTGT TACAAGCATTATTGTAAGTCAATGGCAAAGAGACACTGTTATAATCGTGACCTGGAACAAGATGAAGCATTCATTCCAG CTGGGGAGTCGTTAAAAGACCTCATTGACCAGTCGCAAAGTTCTGGCAGTGGCTCAGGGCTACCATTGCTGGTTCAGCG CACGATTGCCAAACAAATTCAGATGGTGAGGCAAGTTGGAAAGGGACGATATGGTGAAGTGTGGATGGGCAAATGGAGA GGTGAAAAAGTTGCAGTCAAATTGTTTTTCACCACAGAAGAAGCCAGCTGGTTCCGAGAAACAGAGATTTACCAAACTG TTTTAATGCGTCATGAAAACATCCTTGGTTTTATAGCTGCAGATATTAAAGGCACTGGATCCTGGACACAGCTTTACTT GATTACAGATTATCATGAAAATGGATCACTATATGATTTTCTGAAGTGCACTACACTAGACAACAGGGCTCTCCTCAAA CTGGCATACTCTGCTGCATGTGGTCTGTGCCATTTACACACAGAAATCTATGGGACGCAAGGCAAGCCTGCTATAGCAC ACAGGGACCTGAAAAGTAAAAACATTTTGATAAAGAAGAATGGGACATGCTGTATTGCTGACTTGGGTCTCGCAGTCAA GTTTAACAGTGATACAAATGAAGTTGATGTTCCCTTGAATACTAGAGTGGGAACAAAACGTTACATGGCTCCAGAGGTC CTTGATGAAAGCCTGAATAAAAACCATTTTCAACCATACATCATGGCTGACATATACAGTTTTGGGCTGATAATTTGGG AAATGGCTCGACGCTGTGTCACAGGAGGTATTGTTGAAGAGTACCAGTTGCCATACTATGACATGGTGCCAAATGATCC ATCTTATGAGGACATGAGAGAAGTGGTGTGTGTCAAACGTCTGCGCCCAGTAGTATCTAACAGATGGAATAGTGATGAA TGTTTAAGAGCAATATTAAAATTAATGTCTGAATGCTGGGCTCACAATCCTGCTTCAAGACTCACTGCCTTGAGGATCA AGAAGACGCTTGCCAAGATGGTGGAATCACAAGATGTAAAGATTTGACAAAGTAAATTGACATTAATTTTAAT
Citation	Sela-Donenfeld D, Kalcheim C. Localized BMP4-noggin interactions generate the dynamic patterning of noggin expression in somites. Dev Biol. 2002 Jun 15;246(2):311-28.
Copyright	Copyright © 2002 Elsevier Science (USA).
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence was obtained from NCBI (NM_205357.1)