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Human Disease Gene Search
BMPR1A The human orthologue of this gene is associated
Gene Summary Expression Transcript Levels Other Species Expression JBrowse Gene Official Symbol BMPR1A Official Full Name bone morphogenetic protein receptor type 1A CGNC ID 1421 also known as ALK-3, BMPR-1, BRK-1, bone morphogenetic protein receptor type-1A|BMP receptor 1|bone morphogenetic protein receptor, type IA|bone morphogenic protein receptor 1|protein kinase, bone morphogenetic protein receptor, type IA, BMPR1A gene type protein-coding
Genomic Map Sequence Information Gene Expression Orthology Gene Ontology Molecular Function Biological Process Cellular Component
Links to other databases
Entry 1 GEISHA Id BMPR1A.UApcr Data Source GEISHA ISH Analysis Forward cDNA Template Primer AGGAAATGGGGTAACGCTCG Reverse cDNA Template Primer ATTAACCCTCACTAAAGGCAGAGTATGCCAGTTTGAGGAG cDNA Template Length 886 Forward cDNA Template Probe show AGTGCTACTGCTCAGGACATTGTCCAGATGATGCTATTAATAACACATGCATAACTAATGGGCATTGCTTTGCTATCAT
Entry 2 GEISHA Id BMPR-1A.McPherson.2000 Data Source Publication Complete cDNA Template Probe show ATGACTCGACTGAGAGTCTGTGAGCGATTGCTTGGAGCCTACCTGCTTCTCATTCTCCATGTTCAAGGACAAAATCTAG
Citation McPherson CE, Varley JE, Maxwell GD. Expression and regulation of type I BMP receptors during early avian sympathetic ganglion development. Dev Biol. 2000 May 1;221(1):220-32. Copyright Reprinted with permission from Elsevier.
Copyright © 2000 Elsevier B.V. All rights reserved.
Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (AF189777). Thus probe shown is from quail, but it is mapped to its homolog in chick.
Entry 3 GEISHA Id BmprIA.Ashique.2002 Data Source Publication Complete cDNA Template Probe show GGCGCGGCCTGCGTAGGCAACGGAGAGCGGCTTTCTCCTGCTTCGCCTTCTCTCCCTCCGCAAAGGATGAGGAGCCCCC
Citation Ashique AM, Fu K, Richman JM. Signalling via type IA and type IB bone morphogenetic protein receptors (BMPR) regulates intramembranous bone formation, chondrogenesis and feather formation in the chicken embryo. Int J Dev Biol. 2002 Mar;46(2):243-53. Copyright "Reprinted from Int. J. Dev. Biol., 46, Ashique AM, Fu K, Richman JM, Signalling via type IA and type IB bone morphogenetic protein receptors (BMPR) regulates intramembranous bone formation, chondrogenesis and feather formation in the chicken embryo, 243-53, Copyright (2002), with permission from Copyright © 2002 UBC Press". All rights reserved. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc #NM_205357).
Entry 4 GEISHA Id BMPR-1A.Hyre.2003 Data Source Publication Complete cDNA Template Probe show GGCGCGGCCTGCGTAGGCAACGGAGAGCGGCTTTCTCCTGCTTCGCCTTCTCTCCCTCCGCAAAGGATGAGGAGCCCCC
Citation Hyer J, Kuhlman J, Afif E, Mikawa T. Optic cup morphogenesis requires pre-lens ectoderm but not lens differentiation. Dev Biol. 2003 Jul 15;259(2):351-63. Copyright Copyright © 2003 Elsevier Science (USA) All rights reserved. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_205357).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 7-11 stage 11
stage 11
Eye Forebrain
Entry 5 GEISHA Id BMPR1A.Huber.2008 Data Source Publication Complete cDNA Template Probe show GGCGCGGCCTGCGTAGGCAACGGAGAGCGGCTTTCTCCTGCTTCGCCTTCTCTCCCTCCGCAAAGGATGAGGAGCCCCC
Citation Huber K, Franke A, Brühl B, Krispin S, Ernsberger U, Schober A, von Bohlen und Halbach O, Rohrer H, Kalcheim C, Unsicker K. Persistent expression of BMP-4 in embryonic chick adrenal cortical cells and its role in chromaffin cell development. Neural Dev. 2008 Oct 22;3:28. Copyright © 2008 Huber et al; licensee BioMed Central Ltd. (requested from Dr. Unsicker)
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 31 stage 31
stage 31
Intermediate Mesoderm
Entry 6 GEISHA Id BMPR1A.Ishii.2010 Data Source Publication Complete cDNA Template Probe show GGCGCGGCCTGCGTAGGCAACGGAGAGCGGCTTTCTCCTGCTTCGCCTTCTCTCCCTCCGCAAAGGATGAGGAGCCCCC
Citation Ishii Y, Garriock RJ, Navetta AM, Coughlin LE, Mikawa T.. BMP Signals Promote Proepicardial Protrusion Necessary for Recruitment of Coronary Vessel and Epicardial Progenitors to the Heart. Dev Cell. 2010 August 17; 19(2): 307316. Copyright Copyright © 2010 Elsevier Inc. All rights reserved.
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 13-16 stage 16
stage 16
Proepicardium
Entry 7 GEISHA Id BMPR-1A.Zou.1997 Data Source GEISHA ISH Analysis Complete cDNA Template Probe show GGCGCGGCCTGCGTAGGCAACGGAGAGCGGCTTTCTCCTGCTTCGCCTTCTCTCCCTCCGCAAAGGATGAGGAGCCCCC
Citation Zou H, Wieser R, Massagué J, Niswander L. Distinct roles of type I bone morphogenetic protein receptors in the formation and differentiation of cartilage. Genes Dev 1997 Sep 1;11(17):2191-203. Copyright Copyright © 1997, Cold Spring Harbor Laboratory Press Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (Acc. # NM_205357.1).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 25-30 stage 30
Wing Mesenchyme 31-41 stage 32
stage 34
stage 41
Leg Wing
Entry 8 GEISHA Id BRK‐1.Belecky-Adams.2001 Data Source Publication Complete cDNA Template Probe show AAGCTTAACGATTGTCAAGCAGAAGGGCCACTTGCCTTGCACAGGAAGGATTAACAGTGAACAATGACTCGACTGAGAG
Citation Belecky-Adams T, Adler R. Developmental expression patterns of bone morphogenetic proteins, receptors, and binding proteins in the chick retina. J Comp Neurol. 2001 Feb 19;430(4):562-72. Copyright Copyright © 2001 Wiley‐Liss, Inc. Comments The complete cDNA template sequence was obtained from the information from the publication as described in Belecky-Adams et al. 2001. BRK-1 is also known as BMPR1A in NCBI.
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 13-18 stage 18
stage 18
Eye 31-44 stage 34
stage 34
stage 34
stage 44
stage 44
stage 44
stage 44
Retina
Entry 9 GEISHA Id BMPR1A.Sela-Donenfeld.2002 Data Source Publication Complete cDNA Template Probe show GGCGCGGCCTGCGTAGGCAACGGAGAGCGGCTTTCTCCTGCTTCGCCTTCTCTCCCTCCGCAAAGGATGAGGAGCCCCC
Citation Sela-Donenfeld D, Kalcheim C. Localized BMP4-noggin interactions generate the dynamic patterning of noggin expression in somites. Dev Biol. 2002 Jun 15;246(2):311-28. Copyright Copyright © 2002 Elsevier Science (USA). Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence was obtained from NCBI (NM_205357.1)
Data from NCBI Unigene EST ProfileGga.755
Mouse Frog Fruit Fly Zebra Finch Zebrafish
