Geisha

home

contact

Quick Search

Data Class

Enter Text:

Gene Family QuickSearch

HMGCL
3-hydroxymethyl-3-methylglutaryl-CoA lyase

The human orthologue of this gene is associated
with the following human disease:

Gene

Official Symbol	HMGCL
Official Full Name	3-hydroxymethyl-3-methylglutaryl-CoA lyase
CGNC ID	49749
also known as	HL, hydroxymethylglutaryl-CoA lyase, mitochondrial\|3-hydroxy-3-methylglutarate-CoA lyase\|3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase\|HMG-CoA lyase
gene type	protein-coding

Genomic Map

Sequence Information

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.2537

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly	33978			FBgn0031877
Human	3155	ENSG00000117305	MIM:246450	MIM:613898
Mouse	15356	ENSMUSG00000028672	All phenotypic alleles (1):Targeted, knock-out(1)	MGI:96158
Xenopus	100494904, 432233			1002068
Zebrafish	394190	ENSDARG00000021220	ZDB-GENE-040426-958	ZFIN:ZDB-GENE-040426-958

Gene Ontology

Molecular Function	hydroxymethylglutaryl-CoA lyase activity, metal ion binding
Biological Process	ketone body biosynthetic process
Cellular Component	mitochondrial matrix, peroxisome

Links to other databases