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 | TGFBR2
transforming growth factor beta receptor 2 | The human orthologue of this gene is associated
with the following human diseases: |
| Gene | | Official Symbol | TGFBR2 | | Official Full Name | transforming growth factor beta receptor 2 | | CGNC ID | 8694 | | also known as | TGF-beta receptor type-2|TGF-beta receptor type II|TGF-beta type II receptor|TGFR-2|tbetaR-II|transforming growth factor, beta receptor II (70/80kDa)|transforming growth factor-beta receptor type II|transforming growth factor-beta type II receptor | | gene type | protein-coding |
| | Genomic Map | | | Sequence Information | | | Gene Expression | | | Orthology | | | Gene Ontology | | Molecular Function | ATP binding, metal ion binding, protein binding, more...receptor signaling protein serine/threonine kinase activity, SMAD binding, transforming growth factor beta binding, transforming growth factor beta receptor activity, type II, type I transforming growth factor beta receptor binding | | Biological Process | activation of protein kinase activity, brain development, bronchus morphogenesis, more...cardiac epithelial to mesenchymal transition, cartilage development, cell activation, cell migration, embryo development, embryonic cranial skeleton morphogenesis, embryonic hemopoiesis, eye development, gastrulation, heart development, in utero embryonic development, lens development in camera-type eye, lens fiber cell apoptotic process, lung development, lung lobe morphogenesis, mammary gland morphogenesis, mesenchymal cell differentiation, myeloid dendritic cell differentiation, negative regulation of cell adhesion, negative regulation of cell-cell adhesion, palate development, patterning of blood vessels, positive regulation of B cell tolerance induction, positive regulation of cell migration, positive regulation of epithelial cell migration, positive regulation of epithelial to mesenchymal transition, positive regulation of mesenchymal cell proliferation, positive regulation of NK T cell differentiation, positive regulation of T cell tolerance induction, positive regulation of tolerance induction to self antigen, regulation of gene expression, regulation of growth, response to cholesterol, smoothened signaling pathway, trachea formation, transforming growth factor beta receptor signaling pathway, vasculogenesis | | Cellular Component | cell, external side of plasma membrane, integral component of membrane, receptor complex |
| | Links to other databases | |
| GEISHA Id | TGFBR2.UApcr | Data Source | GEISHA ISH Analysis | | Forward cDNA Template Primer | GGAAAAGAAGGAT GATGGGGG | | Reverse cDNA Template Primer | AATTAA CCCTCACTAAAGGTCTCCA ACACCGTTACAGCGAG | cDNA Template Length | 1026 | | Complete cDNA Template Probe | show TTTTTAAAAAATGGCCCCGAATATGGAAAAGAAGGATGAGGGAATGTTTGTGTTCCTGGTACAGGGTGAAGAGTGCAAC
GATGTTCTTATTTTTTCTGCAGTTCCCCATAAGCCAGAGGAGAAAGATGAAATTTCCAAAGTCACAATCATAAGTCTTG
TCCCTTTATTGGTGATTTCTGTTGCTGTGATTGTTATCTTTTATGCCTACCGCACTCACAAGAAGAGGAAGCTCAACAA
GGCCTGGGAGAAGAATGTCAAGCCCAAGAAACATAAAGACTGCAGCGATGTTTGTGCTATTATGTTGGATGATGACCAC
TCAGACATCAGCTCTACCTGTGCCAACAACATCAACCACAACACAGAATTGCTGCCCATTGAACTGGACATTGTTGTTG
GCAAAGGAAGGTTTGCTGAAGTGTATAAAGCCAAATTGAAGCAAAACACATCTGAGCAGTATGAAACTGTGGCAGTAAA
GATCTTCCCCTATGAAGAATATGCCTCCTGGAAGACCGAGAAAGACATTTTTTCAGATGTAAATCTTAAGCATGAGAAC
ATCCTCCAATTCTTGACCGCAGAGGAGCGTAAGACAGATCTTGGTAAACAGTATTGGTTGATCACTGCCTTCCATGCTA
GAGGAAACTTGCAGGAATACCTCACACGGCATATTATCAGCTGGGAAGACCTCTGGAAACTGGGAGGATCCTTGGCCCG
AGGGATTGCCCATCTGCACAGTGATCATACACCTTGTGGTCGCCCTAAAACCCCTATTGTGCACAGAGACCTAAAGAGT
TCCAACATCCTGGTGAAAAATGATTTAACTTGCTGTCTCTGTGACTTTGGGTTATCCCTGAGACTGGACCCTTCTCTCT
CTGTGGATGACTTGGCCAACAGTGGTCAGGTTGGCACAGCAAGGTACATGGGCCCCTGAGGTTCTGGAGTCCAGGATGA
ACCTTGAGAACCATGGAGTCCTTTAAACAAACAGATGTGTACTCCATGGCTTTGGTCCCTCTGGGAAATGACTTCGCTG
TACGTGTTGGAAACCTTAGTGGGTATTTTAAA |
| | Data from NCBI Unigene EST Profile
Unigene ID: Gga.2645 |
MouseFrogFruit FlyZebra FinchZebrafish |
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