GEISHA - A Chicken Embryo Gene Expression Database
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THRB
thyroid hormone receptor beta

The human orthologue of this gene is associated
with the following human diseases:
Gene
Official SymbolTHRB
Official Full Namethyroid hormone receptor beta
CGNC ID49800
also known asCTR BETA 2, TR-BETA, thyroid hormone receptor beta|beta-thyroid hormone receptor|nuclear receptor subfamily 1 group A member 2|thyroid hormone receptor beta 2|thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)
gene typeprotein-coding
Genomic Map
 Ensembl
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
RNANM_001252221
PolypeptideNP_001239150
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST ProfileGga.609
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly
Human7068ENSG00000151090MIM:188570MIM:190160
Mouse21834ENSMUSG00000021779All phenotypic alleles (14):Targeted, knock-out(3) Targeted, other(11) MGI:98743
Xenopus734147, 779054, 3977346070708
Zebrafish30607ENSDARG00000021163ZDB-GENE-990415-268ZFIN:ZDB-GENE-990415-268
Gene Ontology
Molecular Functionprotein binding, sequence-specific DNA binding, steroid hormone receptor activity, thyroid hormone binding, more...thyroid hormone receptor activity, zinc ion binding
Biological Processintracellular receptor signaling pathway
Cellular Componentnucleus
Links to other databases
Entrez Gene396431
Ensembl GeneENSGALG00000011294
KEGGgga:396431
GEISHA IdTSHBeta.Murchow.2005Data SourcePublication
Complete cDNA Template Probeshow
GAATTCCGCCGGGCCGCGCTTCCCCCCGCCCCGCGCCCCCTCCCGGCGACCCTCTCCGCGGCGGAGGGGCCGTTGCGTA
ACGCGTCCGCACGGCGCCGGGGCCGGCAGCGGGCGAGGCGCGCGGTGGCCGCGGCCGGAGTGAGAGAACAGAAAATGAA
GCTCTAGTAAGGTGGCAGTGGTGACAGAAGAAGAACAAGAATGATTACGTATCTGTAACTCTCAGCAGTATGTCAGGGT
ATATACCCAGTTACTTAGACAAGGATGAGCTATGTGTAGTATGTGGGGACAAAGCCACCGGATATCATTATCGCTGCAT
CACTTGTGAAGGTTGCAAGGGATTTTTCAGAAGAACCATTCAGAAAAACCTCCATCCAACCTATTCCTGTAAATATGAA
GGAAAATGTGTGATAGACAAAGTAACAAGAAATCAGTGCCAGGAATGTCGCTTCAAAAAATGTATCTTTGTTGGCATGG
CAACAGATTTGGTGTTGGATGACAGCAAGAGGCTGGCAAAGAGGAAGCTGATAGAAGAAAATCGAGAGAAGAGGCGTCG
GGAAGAGCTGCAGAAAACGATGGTTCACAAACCAGAACCAACAGATGAGGAATGGGAGCTGATCAAAATTGTCACTGAA
GCACATGTGGCCACCAATGCACAAGTAAGCCACTGGAAGCAGAAAAGGAAATTTCTGCCAGAAGACATTGGGCAAGCAC
CAATAGTTAATGCCCCAGAAGGGGGGAAAGTGGATTTAGAAGCCTTCAGCCAGTTTACAAAAATTATCACACCAGCGAT
TACAAGAGTGGTGGATTTTGCCAAAAAGTTACCTATGTTTTTGGAGCTGCCATGTGAAGACCAGATCATCCTTCTGAAA
GTCTGCTGTATGGAGATAATGTCCCTCCGAGCAGCAGTTCGCTATGACCCCGAGAGTGAGACTTTAACGCTAAATGGGG
AGATGGCGGTGACAAGGGGCCAGCTGAAAAATGGGGGTCTTGGCGTAGTTTCTGATGCCATTTTTGACCTGGGCATGTC
TCTTTCTTCATTTAACCTGGATGACACCGAGGTTGCCCTTCTCCAGGCTGTCCTGCTCATGTCATCAGATCGCCCAGGC
CTTGTTTGCGTCGAGAGAATAGAAAAGTGTCAAGAGGGTTTCCTCCTGGCATTTGAACACTACATTAATTACAGAAAAC
ACCATGTTGCACATTTTTGGCCAAAACTGCTGATGAAAGTGACAGATCTGCGAATGATTGGAGCCTGCCATGCCAGCCG
CTTCCTGCACATGAAGGTGGAGTGCCCCACAGAACTCTTCCCTCCATTGTTCCTGGAGGTGTTTGAGGATTAGAGAGAC
TGGAGCGGTCCTCTGCACCCCTGTCGCACTACTGGCTGTCATTCCATTCCATTGCCCAGCTCTTCTCACACCTGTTTGT
TCTTCTTTTGTTATCTTCTGATTCTTGAGGTGGGGTTGGGCTTTTGTTTGAGTTTTTCTCTGGGGTTGCTGGGGGCAGT
TGTATCACTGGATGAAAACATCCTTCTAAACATCCCTTTCTGCTGGTACTTGTGACTATTGCAATTTGTTCTTCAGTCC
TTTGATTGAGCAAATAGAGCCAGCCTACATGGAGGCTCTTCAATGTCACGAAGCATTTAAAGACTTATTTCCAAAGGCC
TGTCTCACAGTACCTCCAAAAGCCCTAGACATCCCATTGTGTTTATATTCTCATGAAATTATGGGCATAACCCCTAAGG
ATAACATCAATGCTCAACACTCACCATGGGTACATATGATATCAAAGAACAGGCACAAGAATTCCATAACCCTGACAAT
AGAGCCAATAGCACTCCAAACACTTCATCAATGTTAAAGGGAAACGGAGGTGAAAATAATTTAATCCCTGGCACAAAGA
TACTGTGCTCCACCTATATATTTTCCTGATATCATGATCTTATGAGGGGACAAATATATAACATATGGGTTTGAACATG
GGGCATGAGCTTTGAAAATCAACACATCAGTTCTAACAGTGCCCACTGAGTTGCCAGGCAAATGTATCAATGAATAACA
GAGACACAAACTGGTACAAATGAATGCACAACGCAAAAGAATGCGGGATCTGAGGAAGTGCAAAACAGGGAATTC
CitationMuchow M, Bossis I, Porter TE. Ontogeny of pituitary thyrotrophs and regulation by endogenous thyroid hormone feedback in the chick embryo. J Endocrinol. 2005 Feb;184(2):407-16.
CopyrightCopyright © 2012 by the Society for Endocrinology
CommentsAs insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # NM_205447.1).
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
31-44
stage 44
stage 44
Pituitary (Rudiment)
 
 Data from NCBI Unigene EST Profile
Unigene ID: Gga.609

Mouse

EmageMGI:98743
EurexpressMGI:98743
MGI GXDMGI:98743

Frog

Xenbase6070708

Fruit Fly

BDGP

Zebra Finch

ZEBrATHRB

Zebrafish

ZFINZDB-GENE-990415-268
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