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ATP2A2
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2

The human orthologue of this gene is associated
with the following human diseases:

Gene

Official Symbol	ATP2A2
Official Full Name	ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
CGNC ID	49809
also known as	SERCA2, sarcoplasmic/endoplasmic reticulum calcium ATPase 2\|ATPase, Ca++ transporting, cardiac muscle, slow twitch 2\|SR Ca(2+)-ATPase 2\|calcium pump 2\|calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform\|endoplasmic reticulum class 1/2 Ca(2+) ATPase, Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 calcium pump 2 (SERCA2), SR Ca(2+)-ATPase 2, Endoplasmic reticulum class 1/2 Ca(2+) ATPase, Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform
gene type	protein-coding

Genomic Map

Sequence Information

Gene Expression

In Situ Hybridization

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly
Human	488	ENSG00000174437	MIM:101900	MIM:108740
Mouse	11938	ENSMUSG00000029467	All phenotypic alleles (5):Targeted, knock-out(2) Targeted, other(3)	MGI:88110
Xenopus	100489059, 446229			1012932
Zebrafish	393940, 568265	ENSDARG00000029439, ENSDARG00000005122	ZDB-GENE-040426-702, ZDB-GENE-030131-867	ZFIN:ZDB-GENE-040426-702, ZFIN:ZDB-GENE-030131-867

Gene Ontology

Molecular Function	ATP binding, S100 protein binding, calcium-transporting ATPase activity, enzyme binding, metal ion binding, more...protein C-terminus binding
Biological Process	ER-nucleus signaling pathway, calcium ion transmembrane transport, calcium ion transport, more...
Cellular Component	integral component of membrane, sarcoplasmic reticulum, sarcoplasmic reticulum membrane

Links to other databases

GEISHA Id	ATP2A2.UApcr	Data Source	GEISHA ISH Analysis
Forward cDNA Template Primer	5’-GCCCCTGCATTGAAGAAAGC-3’
Reverse cDNA Template Primer	5’-AATTAACCCTCACTAAAGGTTGCGTCACGTTTAAAGGCG-3’	cDNA Template Length	777
Complete cDNA Template Probe	show GCCCCTGCATTGAAGAAAGCGGAAATTGGGATCGCTATGGGCTCTGGTACTGCAGTGGCTAAAACTGCTTCTGAAATGG TTTTAGCAGATGATAATTTTTCAACTATTGTAGCTGCTGTGGAAGAAGGGCGTGCAATTTACAACAACATGAAGCAGTT CATCCGTTACTTGATTTCTTCCAATGTTGGAGAAGTTGTTTGCATCTTCTTGACTGCTGCCCTGGGTTTTCCTGAAGCT CTGATCCCTGTCCAGCTGTTATGGGTGAACCTTGTGACGGATGGTCTCCCTGCTACTGCTCTGGGCTTTAATCCTCCTG ATCTCGATATCATGAACAAACCACCCCGCAACCCTAAGGAGCCACTGATCAGTGGGTGGCTCTTCTTCCGCTACCTGGC AATTGGATGTTACGTTGGTGCTGCCACTGTGGGTGCTGCTGCTTGGTGGTTTATTGCTGCTGATGGTGGTCCAAGAGTT ACCTTTTACCAGCTGAGCCATTTTCTGCAGTGCAAAGAGGACAACCCAGACTTTTCTGGTGTCGACTGTGTGGTTTTTG AGTCTCCATATCCAATGACAATGGCTCTCTCTGTACTTGTCACCATAGAGATGTGCAATGCCCTCAACAGTCTGTCAGA AAATCAGTCCCTAATGAGGATGCCTCCATGGGAGAATATCTGGCTGGTGGGAGCGATTTGCTTGTCCATGTCACTCCAC TTCCTTATCCTCTATGTGGAACCGCTGCCGATTATCTTCCAGATCACGCCTTTAAACGTGACGCAA