GEISHA - A Chicken Embryo Gene Expression Database
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ATP2A2
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2

The human orthologue of this gene is associated
with the following human diseases:
Gene
Official SymbolATP2A2
Official Full NameATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
CGNC ID49809
also known asSERCA2, sarcoplasmic/endoplasmic reticulum calcium ATPase 2|ATPase, Ca++ transporting, cardiac muscle, slow twitch 2|SR Ca(2+)-ATPase 2|calcium pump 2|calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform|endoplasmic reticulum class 1/2 Ca(2+) ATPase, Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 calcium pump 2 (SERCA2), SR Ca(2+)-ATPase 2, Endoplasmic reticulum class 1/2 Ca(2+) ATPase, Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform
gene typeprotein-coding
Genomic Map
 Ensembl
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
RNANM_001271973
PolypeptideNP_001258902
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST ProfileGga.42608
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly
Human488ENSG00000174437MIM:101900MIM:108740
Mouse11938ENSMUSG00000029467All phenotypic alleles (5):Targeted, knock-out(2) Targeted, other(3) MGI:88110
Xenopus100489059, 4462291012932
Zebrafish393940, 568265ENSDARG00000029439, ENSDARG00000005122ZDB-GENE-040426-702, ZDB-GENE-030131-867ZFIN:ZDB-GENE-040426-702, ZFIN:ZDB-GENE-030131-867
Gene Ontology
Molecular FunctionATP binding, calcium-transporting ATPase activity, enzyme binding, metal ion binding, more...protein C-terminus binding, S100 protein binding
Biological Processcalcium ion transmembrane transport, calcium ion transport, cellular calcium ion homeostasis, more...ER-nucleus signaling pathway, negative regulation of heart contraction, regulation of the force of heart contraction, response to drug
Cellular Componentintegral component of membrane, sarcoplasmic reticulum, sarcoplasmic reticulum membrane
Links to other databases
Entrez Gene396446
Ensembl GeneENSGALG00000003835
KEGGgga:396446
GEISHA IdATP2A2.UApcrData SourceGEISHA ISH Analysis
Forward cDNA Template Primer5’-GCCCCTGCATTGAAGAAAGC-3’
Reverse cDNA Template Primer5’-AATTAACCCTCACTAAAGGTTGCGTCACGTTTAAAGGCG-3’cDNA Template Length777
Complete cDNA Template Probeshow
GCCCCTGCATTGAAGAAAGCGGAAATTGGGATCGCTATGGGCTCTGGTACTGCAGTGGCTAAAACTGCTTCTGAAATGG
TTTTAGCAGATGATAATTTTTCAACTATTGTAGCTGCTGTGGAAGAAGGGCGTGCAATTTACAACAACATGAAGCAGTT
CATCCGTTACTTGATTTCTTCCAATGTTGGAGAAGTTGTTTGCATCTTCTTGACTGCTGCCCTGGGTTTTCCTGAAGCT
CTGATCCCTGTCCAGCTGTTATGGGTGAACCTTGTGACGGATGGTCTCCCTGCTACTGCTCTGGGCTTTAATCCTCCTG
ATCTCGATATCATGAACAAACCACCCCGCAACCCTAAGGAGCCACTGATCAGTGGGTGGCTCTTCTTCCGCTACCTGGC
AATTGGATGTTACGTTGGTGCTGCCACTGTGGGTGCTGCTGCTTGGTGGTTTATTGCTGCTGATGGTGGTCCAAGAGTT
ACCTTTTACCAGCTGAGCCATTTTCTGCAGTGCAAAGAGGACAACCCAGACTTTTCTGGTGTCGACTGTGTGGTTTTTG
AGTCTCCATATCCAATGACAATGGCTCTCTCTGTACTTGTCACCATAGAGATGTGCAATGCCCTCAACAGTCTGTCAGA
AAATCAGTCCCTAATGAGGATGCCTCCATGGGAGAATATCTGGCTGGTGGGAGCGATTTGCTTGTCCATGTCACTCCAC
TTCCTTATCCTCTATGTGGAACCGCTGCCGATTATCTTCCAGATCACGCCTTTAAACGTGACGCAA
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
4-6
stage 4
stage 5
Epiblast
Extraembryonic Mesoderm
Primitive Streak
 
7-12
stage 8
stage 10
Anterior Intestinal Portal
Forebrain
Head Mesenchyme
Heart Tube
Hindbrain
Lateral Plate Mesoderm
Midbrain
Neural Plate/Tube
Primitive Streak
Somites
extraembryonic mesoderm
 
13-18
stage 14
stage 18
stage 18
Forebrain
Foregut
Head Mesenchyme
Heart
Hindbrain
Midbrain
Myotome
Neural Plate/Tube
Pharyngeal Arches and Clefts
Proepicardium
Sclerotome
Sinus Venosus
Somites
Widespread Expression
Strong expression in heart and myotome, widespread expression
19-24
stage 19
stage 22
stage 23
stage 23
stage 23
stage 23
Atria
Eye
Liver
Myotome
Nephric Ducts
Neural Plate/Tube
Pharyngeal Arches and Clefts
Sclerotome
Sinus Venosus
Ventricles
Widespread Expression
Strong expression in myotome and heart; lesser widespread expression
25-26
stage 26
stage 26
stage 26
stage 26
stage 26
Atria
Ear/Otic Placode
Foregut
Head Mesenchyme
Leg Mesenchyme
Liver
Mesonephros
Myotome
Pharyngeal Arches and Clefts
Sinus Venosus
Spinal Cord
Spinal Ganglia and Nerves
Ventricles
Wing Mesenchyme
 
 Data from NCBI Unigene EST Profile
Unigene ID: Gga.42608

Mouse

EmageMGI:88110
EurexpressMGI:88110
MGI GXDMGI:88110

Frog

Xenbase1012932

Fruit Fly

BDGP

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-040426-702, ZDB-GENE-030131-867
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