Geisha

home

contact

A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

Quick Search

Data Class

Enter Text:

Gene Family QuickSearch

	Transcription Factors
	Growth Factors
	Receptors
	MicroRNAs

Human Disease Gene Search

	Downloads
	Protocols
	About GEISHA
	Contact Us

	Transgenic Birds
	Model Organism Databases
	Gene Expression Databases
	Genomic Resources
	Anatomical Atlases
	Chicken Stage Series

GLUL
glutamate-ammonia ligase

The human orthologue of this gene is associated
with the following human disease:

Glutamine deficiency, congenital

Gene

Official Symbol	GLUL
Official Full Name	glutamate-ammonia ligase
CGNC ID	2689
also known as	p42, glutamine synthetase\|GS\|glutamate decarboxylase\|glutamate-ammonia ligase (glutamine synthase)\|glutamate-ammonia ligase (glutamine synthetase), Glutamine synthetase, Glutamate--ammonia ligase, GLUL
gene type	protein-coding

Genomic Map

	Ensembl
	NCBI
	UCSC
	Gallus-Browse

Sequence Information

Genomic
RNA	NM_205493
Polypeptide	NP_990824
Sequence Clusters/ESTs	Unigene

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.2464

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly	32087			FBgn0001145
Human	2752	ENSG00000135821	MIM:610015	MIM:138290
Mouse	14645	ENSMUSG00000026473	All phenotypic alleles (5):Targeted, other(5)	MGI:95739
Xenopus	394915, 444294, 398556			5923224
Zebrafish	336473, 321969	ENSDARG00000017339	ZDB-GENE-030131-8417, ZDB-GENE-030131-688	ZFIN:ZDB-GENE-030131-8417, ZFIN:ZDB-GENE-030131-688

Gene Ontology

Molecular Function	ATP binding, glutamate-ammonia ligase activity, glutamate decarboxylase activity
Biological Process	glutamine biosynthetic process
Cellular Component	mitochondrion

Links to other databases

Entrez Gene	396489
Ensembl Gene	ENSGALG00000003678
KEGG	gga:396489

Entry 1

GEISHA Id	GLUL.Domowicz.2008	Data Source	Publication
Complete cDNA Template Probe	show GGGCGCGGCCCCCGGGAGCCGAGCGTGGGAGCCCCGCGCCGAGCCCCTGCCCGCAGCCCAGCCCAGGACAGCCCTCGCC AGCTCCGCAGCCATGGCCACCTCGGCGAGCTCCCACCTGAGCAAAGCCATCAAGCACATGTACATGAAGCTGCCGCAGG GTGAGAAGGTCCAAGCCATGTACATCTGGATCGACGGGACTGGGGAGCACCTCCGCTGCAAAACCCGCACTCTGGACCA CGAACCCAAGAGCCTGGAAGATCTCCCCGAGTGGAACTTTGATGGCTCCAGCACCTTCCAAGCCGAAGGCTCCAACAGC GACATGTACCTGCGACCTGCTGCCATGTTCCGGGACCCTTTTCGCAAGGATCCCAACAAATTAGTTCTCTGTGAGGTCT TCAAATACAACCGCCAGTCTGCAGACACAAATCTTCGGCACACCTGTAGGCGGATTATGGATATGGTGTCCAACCAGCA CCCCTGGTTTGGGATGGAGCAGGAGTACACCCTTCTGGGAACAGATGGTCATCCGTTTGGCTGGCCTTCCAATTGCTTC CCTGGACCCCAAGGTCCGTACTACTGCGGTGTAGGAGCTGACAAAGCCTATGGCAGAGACATTGTGGAGGCCCACTACC GAGCGTGCCTGTATGCTGGTGTGAAAATTGGAGGAACCAACGCAGAAGTGATGCCAGCCCAGTGGGAGTTCCAGGTGGG ACCGTGCGAAGGGATTGAGATGGGGGATCACCTCTGGATAGCACGTTTCATCCTCCACCGGGTGTGCGAAGACTTTGGT GTCATTGTGTCCTTCGATCCCAAACCCATCCCTGGGAACTGGAACGGTGCTGGCTGTCACACCAACTTCAGCACCAAGA ACATGAGGGAAGATGGAGGTCTCAAGCACATCGAGGAGGCCATCGAGAAGCTGAGCAAGCGCCACCAGTACCACATCCG TGCCTACGACCCCAAAGGAGGGCTGGACAACGCCCGGCGCCTGACGGGCTTCCACGAGACGTCCAGCATCCACGAGTTC TCCGCCGGCGTGGCCAACCGCGGCGCCAGCATCCGCATCCCACGCAACGTGGGCCATGAGAAGAAAGGCTACTTCGAGG ACCGCGGGCCTTCAGCCAACTGCGATCCCTACGCCGTGACGGAGGCCCTGGTCCGTACGTGTCTCCTCAACGAAACCGG GGACGAGCCTTTTGAGTACAAGAACTAAGTGGACTCGTGCCCACAGACACCGCCTTCCCCCTCCCCCCACCCCCCCCGT GCTCCCCGTACCCCTAAACTTCCCTTCTAGTTGTAATCCTGAGGGTACAAGATAACACCTTCGTGTCTCAGTAACTCTT GTTGTTTTGAGGTGGGGGAGGAGGGCAGGTTTAGTTTTATTAATGTCTGTTTGTCATTGACTCTTCAAAAGGCGAGAGG AGGAGGGGGGTGGGGGGGGGGTAGATGATTTTTAACCACTGTTTTGTTTTGGTTTTTTTTTTTGTCTAATTCATCTGTA CATCTGGTGGGATCCAGTGGCTTCAGGGACAGGCTACACACAAAGCCAGCAGACGAGAGGAAAGTGGAAAATTATGGCC GACTTCCCCAAATTTGATTGTTAGGCCCAGCGCTGGGGGGCTCTCTCCCAGCGGCTGATGGTTCTCAAGGCATAGCATC CCAAGAAGGGCAGGCAGGGACTGGGATGGAACCCAGCTCTGTCCCGTGGTGTGATGGGGAAGTCTTCAGCCTATTGGCA CTGTCACATTTCTAGGCTCCTTCTTGGCATCGAGCGTGTGGTGTAGGAGCACCTAGGAGAGCTCCTCGTCCTGTCATTG GAAGTCAGGCGATCTCCCGCTCATAACACAGAGTGAAGTAGTATTTTTCTATTTAAATGTAAAAACGAACAAAAAAAAT TATATATGGAAGCGGAGGGGGGGAGGGGGGGGGAGGTTGTGTTTCTAGTTTTTGGGGTTTTTTTTTTTTTTTCTTTTAA AGAAGAAAAAGATGCTGTCCCAGGGGCTCGACCACAACAGTGGCAGAGCTGATGGGGATCGCGTTCAGAGGGCCTCCAG GTGGGACTGAGGGAGAGCTTGGAGGGCTCAGTGGGGAAGACTCAGAGGAATGGAGCTTGCAGGAGGCAATTCCCAGACC TGGGAAGCCCACGGGGACGTTTATCACTGTAACTCAAGTAGCCATGAAGTGCTCGTGTGGATGAGGGTGAGGAAGGCGT TTGGAACTAGGAGTTGGCTGGTCAACTTCANCACGTTCTGGACCAGAGCTGTGGGTGCTTCACTTTCCAGTGAGGTTTG CACGTCACTAAAGCAGGGCTTTTGATGGGTGAAATTTTAGATGACTTTTTTTTTTTTCTTTTTTCTTGTAATGTACTTA GTTTCTAAAAACTGAGTGGTTTTACAGAGACCGTCAATGTCACTGTTGTGTCCTGGCCGTGGGACTGCCTGCCTCCGCT GATGGTGGCTGGGAGAAAGGGGAAGGATCCATCCCTCCCAGGCAGCCCTGTGCTTCCCAGCTCGGGTTGGGGGGTACAA ACGTTCCAGGATCTTTGGGTATCTTAGCTGGTGCCAGTTATATTCCGTTGCATTTGAACCTTCTTCCAAATAGTTTTTT TTTAATAATTAAAAAAAAAAGAGAGATGGAAATGTTAATTCTGACTTTTTCCTCCTTTCTGTGCTTCCTGGCAACTTCT TTTGTACGTGTTTTGTCTTTACTTAAAGGTAATTTTATCCTG
Citation	Domowicz MS, Sanders TA, Ragsdale CW, Schwartz NB. Aggrecan is expressed by embryonic brain glia and regulates astrocyte development. Dev Biol. 2008 Mar 1;315(1):114-24. Epub 2008 Jan 22.
Copyright	Copyright © 2008 Published by Elsevier Inc.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. The sequence below was obtained from NCBI (acc #NM_205493.1)

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

31-44

stage 38

stage 44

Hindbrain
Mesencephalon
Metencephalon
Midbrain

Cerebullum

Entry 2

GEISHA Id	GLUL.Gotoh.2011	Data Source	Publication
Complete cDNA Template Probe	show TCTCCCCGAGTGGAACTTTGATGGCTCCAGCACCTTCCAAGCCGAAGGCTCCAACAGCGACATGTACCTGCGACCTGCT GCCATGTTCCGGGACCCTTTTCGCAAGGATCCCAACAAATTAGTTCTCTGTGAGGTCTTCAAATACAACCGCCAGTCTG CAGACACAAATCTTCGGCACACCTGTAGGCGGATTATGGATATGGTGTCCAACCAGCACCCCTGGTTTGGGATGGAGCA GGAGTACACCCTTCTGGGAACAGATGGTCATCCGTTTGGCTGGCCTTCCAATTGCTTCCCTGGACCCCAAGGTCCGTAC TACTGCGGTGTAGGAGCTGACAAAGCCTATGGCAGAGACATTGTGGAGGCCCACTACCGAGCGTGCCTGTATGCTGGTG TGAAAATTGGAGGAACCAACGCAGAAGTGATGCCAGCCCAGTGGGAGTTCCAGGTGGGACCGTGCGAAGGGATTGAGAT GGGGGATCACCTCTGGATAGCACGTTTCATCCTCCACCGGGTGTGCGAAGACTTTGGTGTCATTGTGTCCTTCGATCCC AAACCCATCCCTGGGAACTGGAACGGTGCTGGCTGTCACACCAACTTCAGCACCAAGAACATGAGGGAAGATGGAGGTC TCAAGCACATCGAGGAGGCCATCGAGAAGCTGAGCAAGCGCCACCAGTACCACATCCGTGCCTACGACCCCAAAGGAGG GCTGGACAACGCCCGGCGCCTGACGGGCTTCCACGAGACGTCCAGCATCCACGAGTTCTCCGCCGGCGTGGCCAACCGC GGCGCCAGCATCCGCATCCCACGCAACGTGGGCCATGAGAAGAAAGGCTACTTCGAGGACCGCGGGCCTTCAGCCAACT GCGATCCCTACGCCGTGACGGAGGCCCTGGTCCGTACGTGTCTCCT
Citation	Gotoh H, Ueda T, Uno A, Ohuchi H, Ikenaka K, Ono K. Expression of myelin genes in the developing chick retina. Gene Expr Patterns. 2011 Dec;11(8):471-5. Epub 2011 Aug 19.
Copyright	Copyright © 2011 Elsevier B.V. All rights reserved.
Comments	NM_205493.1; nt 259-1173