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ACE
angiotensin I converting enzyme

The human orthologue of this gene is associated
with the following human diseases:

Gene

Official Symbol	ACE
Official Full Name	angiotensin I converting enzyme
CGNC ID	306
also known as	DCP1, angiotensin-converting enzyme\|angiotensin I converting enzyme (peptidyl-dipeptidase A) 1\|dipeptidyl carboxypeptidase I\|kininase II
gene type	protein-coding

Genomic Map

Sequence Information

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.3781

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly
Human	1636	ENSG00000159640	MIM:104300	MIM:106180
Mouse	11421	ENSMUSG00000020681	All phenotypic alleles (14):Targeted, knock-out(6) Targeted, other(8)	MGI:87874
Xenopus	100144634			479788
Zebrafish	565980	ENSDARG00000079166	ZDB-GENE-030131-1826	ZFIN:ZDB-GENE-030131-1826

Gene Ontology

Molecular Function	carboxypeptidase activity, metal ion binding, metallopeptidase activity, peptidyl-dipeptidase activity
Biological Process	proteolysis
Cellular Component	integral component of membrane

Links to other databases

GEISHA Id	ACE.Savary.2005	Data Source	Publication
Complete cDNA Template Probe	show CGCTGGGGCACTCCTGGAGTATTTCAGCCCTGTCACCACCTGGTTGCAGGAGCAGAACAACAAGACCAATGAGGTGCTG GGCTGGCCTGAGTTTGACTGGCGTCCCCCCATCCCTGAAGGCTACCCTGAAGGCATCGACAAAATAGTAGATGAAGCAC AAGCTAAAGAGTTCTTGTCCGAGTACAACAGCACAGCTGAGGTGGTGTGGAATGCTTACACTGAGGCATCTTGGGAGTA CAACACCAACATCACTGACCACAACAAGGAAGTCATGCTGGAGAAGAACTTGGCCATGTCCAAGCACACCATTGAGTAT GGCATGAGAGCCCGGCAGTTCGACCCCTCGGACTTCCAGGACGAAACTGTCACCCGCATCCTCAATAAGCTGAGTGTGC TTGAGAGGGCAGCCCTGCCAGAGGATGAGCTGAAGGAGTACAACACCCTCCTCTCAGATATGGAGACCACATACAGCGT AGCCAAGGTCTGCAGGGAGAACAACACTTGCCACCCCTTGGATCCTGACCTCACGGACATCCTGGCTACCTCACGAGAC TACAACGAGCTCCTCTTTGCCTGGAAGGGCTGGCGGGATGCTTCTGGGGCGAAAATCAAGGACAAATACAAGCGATACG TGGAACTGAGCAACAAGGCAGCTGTGCTCAATGGATACACAGACAATGGGGCTTACTGGAGATCCCTGTATGAGACACC CACCTTTGAGGAAGATCTGGAGAGGCTGTACCTGCAGCTGCAGCCCCTGTACCTCAACTTGCATGCCTACGTACGTCGT GCCCTGTACAACAAATATGGAGCAGAGCACATAAGCCTGAAGGGTCCCATTCCTGCTCACTTGCTGGGCAACATGTGGG CCCAGTCGTGGTCC
Citation	Savary K, Michaud A, Favier J, Larger E, Corvol P, Gasc JM. Role of the renin-angiotensin system in primitive erythropoiesis in the chick embryo. Blood. 2005 Jan 1;105(1):103-10. Epub 2004 Sep 14.
Copyright	Copyright © 2012 by American Society of Hematology
Comments	The probe was amplified by PCR using the following primers: 5′- CGC TGG GGC ACT CCT GGA GTA TT-3′ and 5′-GGA CCA TGA CTG GGC CCA CAT-3′ and was extracted from NCBI Acc# NM_001167732.1.