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 | STAT3
signal transducer and activator of transcription 3 | The human orthologue of this gene is associated
with the following human disease: |
| Gene | | Official Symbol | STAT3 | | Official Full Name | signal transducer and activator of transcription 3 | | CGNC ID | 2374 | | also known as | signal transducer and activator of transcription 3|signal transducer and activator of transcription 3 (acute-phase response factor), STAT3, Signal transducer and activator of transcription 3 | | gene type | protein-coding |
| | Genomic Map | | | Sequence Information | | | Gene Expression | | | Orthology | | | Gene Ontology | | Molecular Function | DNA binding, RNA polymerase II repressing transcription factor binding, calcium ion binding, more...ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, protein dimerization activity, protein kinase binding, protein phosphatase binding, sequence-specific DNA binding, signal transducer activity, transcription factor binding, transcription regulatory region DNA binding | | Biological Process | JAK-STAT cascade involved in growth hormone signaling pathway, astrocyte differentiation, more...cell proliferation, eating behavior, eye photoreceptor cell differentiation, glucose homeostasis, interleukin-6-mediated signaling pathway, negative regulation of neuron migration, phosphorylation, positive regulation of Notch signaling pathway, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-templated, protein import into nucleus, radial glial cell differentiation, regulation of multicellular organism growth, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-templated, sexual reproduction, stem cell maintenance, temperature homeostasis, transcription from RNA polymerase II promoter | | Cellular Component | cytoplasm, nucleus, plasma membrane |
| | Links to other databases | |
| GEISHA Id | ChEST622p14 | Data Source | GEISHA ISH Analysis | | Forward cDNA Template Probe | show GCGGCTCGAGCCGCCCCGCCCGGGACCGCCGGGTTCCGGAGCCGGCCAGGATGGCGCAGTGGAACCAACTGCAGCAGCT
CGACACGCGGTACCTGGAGCAGCTCCACCAGCTTTACAGCGACAGCTTCCCCATGGAGCTGCGGCAGTTCCTGGCCCCG
TGGATTGAGAGCCAGGACTGGGCATACGCTGCCAACAAGGAGTCGCATGCCACACTGGTGTTCCACAACCTGCTGGGGG
AGATCGACCAGCAGTACAGCCGCTTCCTGCAGGAATCCAATGTCTTGTACCAGCACAACCTGCGGCGCATCAAGCAGTT
CCTGCAGAGCAGATATTTGGAGAAGCCGATGGAAATAGCCCGCATTGTGGCTCGCTGCCTGTGGGAAGAGTCACGGCTC
CTCCAGACAGCTGCCACTGCAGCCCAGCAAGGGGGACAGGCGACACATCCAACAGCAGCTGTAGTGACAGAAAAGCAGC
AGATGCTGGAACAGCATCTGCAGGATGTAAGGAAGAGAGTGCAGGATCTGGAGCAGAAGATGAAAGTGGTGGAGAATCT
CCAGGATGACTTTGATTTTAACTACAAGACTTTGAAAAGCCAAGGAGACATGCAGGTCCATCAGCTGCGCAGGGAGCCA
GGGCAGCACCAAAGGCAGCATCCCCCTGTGCCCCCTCACTGGGGGGAGGGGACTGCAGCCCCTGGGCAGCACCGGGCAC
GGTGTGAGGGCAGAACAGGGGTCTGGGGGCTGCCCACGGGCACAGGAAATCGGCCCCCTGCAGTCGGTAGATGCTCAG | | Comments | No specific expression detected stages 5-25. |
no images MouseFrogFruit FlyZebra FinchZebrafish |
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