GEISHA - A Chicken Embryo Gene Expression Database
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MYD88
myeloid differentiation primary response 88

The human orthologue of this gene is associated
with the following human disease:
Gene
Official SymbolMYD88
Official Full Namemyeloid differentiation primary response 88
CGNC ID4445
also known asmyeloid differentiation primary response protein MyD88|myeloid differentiation primary response gene (88)
gene typeprotein-coding
Genomic Map
 Ensembl
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
RNANM_001030962
PolypeptideNP_001026133
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST ProfileGga.17397
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly
Human4615ENSG00000172936MIM:612260MIM:602170
Mouse17874ENSMUSG00000032508All phenotypic alleles (13):Chemically induced(5) Targeted, knock-out(4) Targeted, other(4) MGI:108005
Xenopus549591, 394321, 734302486649
Zebrafish403145ENSDARG00000010169ZDB-GENE-040219-3ZFIN:ZDB-GENE-040219-3
Gene Ontology
Molecular Functionmolecular_function, TIR domain binding
Biological Processactivation of MAPK activity involved in innate immune response, more...defense response to Gram-positive bacterium, immunoglobulin mediated immune response, inflammatory response, innate immune response, lipopolysaccharide-mediated signaling pathway, MyD88-dependent toll-like receptor signaling pathway, negative regulation of growth of symbiont in host, positive regulation of chemokine biosynthetic process, positive regulation of I-kappaB kinase/NF-kappaB signaling, positive regulation of interleukin-17 production, positive regulation of interleukin-23 production, positive regulation of interleukin-6 production, positive regulation of JNK cascade, positive regulation of lymphocyte proliferation, positive regulation of NF-kappaB import into nucleus, positive regulation of NF-kappaB transcription factor activity, positive regulation of tumor necrosis factor production, regulation of inflammatory response, response to molecule of fungal origin, response to peptidoglycan, response to virus, toll-like receptor 15 signaling pathway, toll-like receptor 21 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 7 signaling pathway, toll-like receptor signaling pathway, type I interferon biosynthetic process
Cellular Componentcytoplasm, cytosol, nucleus, plasma membrane
Links to other databases
Entrez Gene420420
Ensembl GeneENSGALG00000005947
KEGGgga:420420
No expression data available.
 Data from NCBI Unigene EST Profile
Unigene ID: Gga.17397

Mouse

EmageMGI:108005
EurexpressMGI:108005
MGI GXDMGI:108005

Frog

Xenbase486649

Fruit Fly

BDGP

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-040219-3
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