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TGFB2
transforming growth factor beta 2| Gene | | Official Symbol | TGFB2 | | Official Full Name | transforming growth factor beta 2 | | BirdBase ID | BB-GG18504 | | CGNC ID | 51471 | | also known as | TGF-beta-2, transforming growth factor beta-2 proprotein|TGF beta2|transforming growth factor-beta2 | | gene type | protein-coding |
| | Genomic Map | | | Sequence Information | | | Gene Expression | | In Situ Hybridization | GEISHA | | EST Profile | |
| | Orthology | | | Gene Ontology | | Molecular Function | beta-amyloid binding, growth factor activity, protein homodimerization activity, receptor binding, more...receptor signaling protein serine/threonine kinase activity, transforming growth factor beta receptor binding, type II transforming growth factor beta receptor binding | | Biological Process | activation of protein kinase activity, cardiac epithelial to mesenchymal transition, more...cardiac muscle cell proliferation, cardioblast differentiation, cartilage development, cell-cell junction organization, cell cycle arrest, cell death, cell growth, cell migration, cell morphogenesis, collagen fibril organization, dopamine biosynthetic process, embryo development, embryo development ending in birth or egg hatching, embryonic digestive tract development, endothelial cell activation, epithelial to mesenchymal transition, epithelial to mesenchymal transition involved in endocardial cushion formation, extrinsic apoptotic signaling pathway, eye development, glial cell migration, gonad development, heart development, heart morphogenesis, hemopoiesis, lung development, negative regulation of alkaline phosphatase activity, negative regulation of cell adhesion, negative regulation of cell proliferation, negative regulation of epithelial cell proliferation, negative regulation of macrophage cytokine production, nervous system development, neural tube development, neuron development, neutrophil chemotaxis, organ development, pathway-restricted SMAD protein phosphorylation, positive regulation of cardioblast differentiation, positive regulation of catagen, positive regulation of cell adhesion mediated by integrin, positive regulation of cell cycle, positive regulation of cell division, positive regulation of cell growth, positive regulation of cell proliferation, positive regulation of epithelial cell migration, positive regulation of epithelial to mesenchymal transition, positive regulation of heart contraction, positive regulation of immune response, positive regulation of integrin biosynthetic process, positive regulation of neuron apoptotic process, positive regulation of phosphatidylinositol 3-kinase signaling, positive regulation of protein secretion, positive regulation of stress-activated MAPK cascade, protein phosphorylation, regulation of cell differentiation, regulation of cell proliferation, regulation of growth, regulation of transforming growth factor beta2 production, response to drug, response to hypoxia, response to progesterone, signal transduction by phosphorylation, skeletal muscle tissue development, SMAD protein import into nucleus, somatic stem cell division, somitogenesis, spleen development, transforming growth factor beta receptor signaling pathway, wound healing | | Cellular Component | axon, extracellular matrix, extracellular region, extracellular space, neuronal cell body |
| | Links to other databases | |
Entry 1| GEISHA Id | TGFB2.UApcr | Data Source | GEISHA ISH Analysis | | Forward cDNA Template Primer | CGGCGATGGAGAAAAATGC | | Reverse cDNA Template Primer | AATTAA CCCTCACTAAAGGATGTAGTAGAGGATGGTGAGGGC | cDNA Template Length | 775 | | Complete cDNA Template Probe | show GTCCACTTGGTGAGGCTGAGTTCAGGGTCTTCCGCCTGCAGAACTCAAAGGCGCGGGTCTCGGAGCAGCGGATAGAGCT
GTACCAGGTTCTGAAATCCAAAGAATTATCATCACCAGGACAGCGTTACATTGACAGCAAAGTGGTTAAAACAAGAGCT
GAAGGAGAATGGTTGTCTTTTGATGTCACTGAGGCTGTACATGAATGGCTCCATCACAGAGACAGGAACCTTGGATTTA
AGATAAGCTTACATTGTCCATGCTGCACCTTTGTGCCTTCCAATAATTATATCATCCCAAATAAAAGTGAGGAGCTTGA
AGCAAGATTTGCAGGTATTGATGACTACACATATTCCAGTGGTGATGTGAAAGCTTTAAAGTCCAATAGGAAAAAATAC
AGTGGGAAGACCCCACATCTTCTGCTAATGTTGTTACCCTCCTACAGACTTGAGTCGCAACAGCCCAGTCGGCGGAAGA
AGCGTGCTCTAGATGCTGCCTATTGTTTTAGGAATGTGCAGGATAATTGCTGCCTGCGTCCACTTTATATTGACTTCAA
GAGGGATCTTGGCTGGAAATGGATTCATGAACCTAAAGGATATCATGCCAATTTCTGTGCAGGAGCCTGCCCATATTTA
TGGAGCTCAGATACTCAGCACAGCAGAGTACTCAGCTGTATAACACCATAAATCCAGAAGCTTCTGCCTCTCCGTGCTG
CGTGTCCCAGGATTTAGG |
Entry 2| GEISHA Id | TGFB2.Yamagishi.2012 | Data Source | Publication | | Complete cDNA Template Probe | show CTCTCAGCCTGTCTACCTGCAGCACCCTCGACATGGATCAGTTCATGCGCAAGAGGATCGAGGCGATCCGGGGGCAGAT
CCTGAGCAAGCTGAAGCTCACCAGCCCCCCGGACGAGTACCCCGAGCCCGAGGAGGTGCCCCCGGAGGTCATCTCCATC
TACAACAGCACCAGGGACCTGCTGCAGGAGAAAGCCAACCACAGAGCTGCCACTTGCGAGAGGGAGCGGAGCGACGAGG
AGTACTACGCCAAAGAAGTTTACAAAATAGACATGCAGCCTTTTTACCCCGAAAATGCCATCCCACCAAGCTATTACAG
CCTTTACTTCAGAATTGTTAGATTTGACGTCTCGGCGATGGAGAAAAATGCGTCCAACTTGGTGAAGGCTGAGTTCAGG
GTCTTCCGCCTGCAGAACTCAAAGGCGCGGGTCTCGGAGCAGCGGATAGAGCTGTACCAGGTTCTGAAATCCAAAGAAT
TATCATCACCAGGACAGCGTTACATTGACAGCAAAGTGGTTAAAACAAGAGCTGAAGGAGAATGGTTGTCTTTTGATGT
CACTGAGGCTGTACATGAATGGCTCCATCACAGAGACAGGAACCTTGGATTTAAGATAAGCTTACATTGTCCATGCTGC | | Citation | Yamagishi T, Ando K, Nakamura H, Nakajima Y.
Expression of the Tgfβ2 gene during chick embryogenesis.
Anat Rec (Hoboken). 2012 Feb;295(2):257-67. doi: 10.1002/ar.22400. Epub 2011 Dec 21.
| | Comments | The cDNA template used to generate the probe was obtained by PCR using the information provided in the publication. |
Entry 3| GEISHA Id | TGFBETA2.GarciaCampmany.2007 | Data Source | Publication | | Complete cDNA Template Probe | show TCTTTTTTTTTTTTAACTGCCGCTCTCTCCACCCCCGACTCTCACTAGGCTGCTTTTTTATTTTTTTGTATCACTATTG
GTATTTTTTCCACTGGCGACTCCCGTGCGTTTGTGGATTGCAAGCCGTCCTTGCAGTCCGGTTGTTCACTGCATTTTGT
CTGCAGATCCTCCCTTTGTTTGCACACATCCCCCTGTTATTTTTTAATATTAACCCCCCACCCCCCCACCCCCACCGTT
GTCGTTCGTGGTTAAAGTCACTCTTTTTTCGGGGGGCGCTGTATTTAAGCACTTAAGATGCACTGCTATCTCCTGAGCG
TGTTCCTCACCCTGGATCTGGCCGCCGTGGCTCTCAGCCTGTCTACCTGCAGCACCCTCGACATGGATCAGTTCATGCG
CAAGAGGATCGAGGCGATCCGGGGGCAGATCCTGAGCAAGCTGAAGCTCACCAGCCCCCCGGACGAGTACCCCGAGCCC
GAGGAGGTGCCCCCGGAGGTCATCTCCATCTACAACAGCACCAGGGACCTGCTGCAGGAGAAAGCCAACCACAGAGCTG
CCACTTGCGAGAGGGAGCGGAGCGACGAGGAGTACTACGCCAAAGAAGTTTACAAAATAGACATGCAGCCTTTTTACCC
CGAAAATGCCATCCCACCAAGCTATTACAGCCTTTACTTCAGAATTGTTAGATTTGACGTCTCGGCGATGGAGAAAAAT
GCGTCCAACTTGGTGAAGGCTGAGTTCAGGGTCTTCCGCCTGCAGAACTCAAAGGCGCGGGTCTCGGAGCAGCGGATAG
AGCTGTACCAGGTTCTGAAATCCAAAGAATTATCATCACCAGGACAGCGTTACATTGACAGCAAAGTGGTTAAAACAAG
AGCTGAAGGAGAATGGTTGTCTTTTGATGTCACTGAGGCTGTACATGAATGGCTCCATCACAGAGACAGGAACCTTGGA
TTTAAGATAAGCTTACATTGTCCATGCTGCACCTTTGTGCCTTCCAATAATTATATCATCCCAAATAAAAGTGAGGAGC
TTGAAGCAAGATTTGCAGGTATTGATGACTACACATATTCCAGTGGTGATGTGAAAGCTTTAAAGTCCAATAGGAAAAA
ATACAGTGGGAAGACCCCACATCTTCTGCTAATGTTGTTACCCTCCTACAGACTTGAGTCGCAACAGCCCAGTCGGCGG
AAGAAGCGTGCTCTAGATGCTGCCTATTGTTTTAGGAATGTGCAGGATAATTGCTGCCTGCGTCCACTTTATATTGACT
TCAAGAGGGATCTTGGCTGGAAATGGATTCATGAACCTAAAGGATATCATGCCAATTTCTGTGCAGGAGCCTGCCCATA
TTTATGGAGCTCAGATACTCAGCACAGCAGAGTACTCAGCTTGTATAACACCATAAATCCAGAAGCTTCTGCCTCTCCG
TGCTGCGTGTCCCAGGATTTAGAGCCCCTCACCATCCTCTACTACATTGGCAAAACACCCAAAATCGAACAGCTGTCCA
ACATGATTGTAAAGTCTTGCAAATGCAGCTAAAGGATACCCCAGAAACAGCGTGACGTGTGTGTATCAAAAAAAAAAAA
AGTAAAAAATAAAAATAATAACCAAGGAAAAAAAGAAAGAGAGAGCGAGGAGGAAAGAAAGCAAAACGAAAACCCAGGT
TCATCAGTGTTAAAAGGGGAAAAAAAAACAAAGAAGAAAAAAAAGCGGTACTAGTCTGAACTGTTTGAAAGTTTGTTTT
TGTCTTTTTGTTTTTAAACTGGCATCTGAAGCAAAACATTGAAGGCCTTTATCTTACATTTCACCTACACATAGTGTGA
GATAGACAAGAAGCAAAGTTAAAGCAAAAAAAAAAGAAACCTTTTAAAAAATAAACACTGGAAGAAATTTGTTAGTGTT
ACTATGTGAAAGGAAAAAAACAGGAAAATCCCATGAAGTGGAGTTGCTGTATCTGTCCCGTGCCTTACTTGATCTCTCT
GTATTGTTATGCAATAGGCATCCTACCCATTCCTCTTAGTTGTAGAGTTAACAGTGCATTATTTATTTGTGTGTAAAAA
CTATCAAATGAACATTTCCATATCGCCATTGGAAAAGGAAAACCAGCAAATGTGGACAAAATGGAGACCAAATAAGCTG
CCAGAAACACATAGAAAGCCTAAAGGAACGCAAGCTCAAAAGTGTCAGAAAGTAATGGTTAGTTTAGTTGGATTTAAAT
AGAAATCAGTTATTACACTATTGAGAAACTCTGCCTTTAAAATACCTTATTTTTCATGCCAGCTGCCTGGAGAGGCTTC
TTGTAAGGTCTCAAACCCTTGTTTTAAATACTGAATAACTTACTAATAAAGGACACTCTGTTTCAGTCTCAAAGACAAG
TCTATAAGATTTTTTTTTTTTTTACTGTAAATGATTTAAATGTCAGTTTAGTAAACCAGTGAAATATTTAACATGTACT
GGTCTAATCTTCAGACCTTAATATGTTGCTGTATAGCTATGCTATGGGATTTTTTGTTCTTTTGGTATATGTAACCATA
CCTAGAGTATTGCAATAGGTGGGTAGTAAAAGCCAGCTTAATTGGAAACATATCTGTAGATCTCTATTTGTAAACTATT
AAAAAATTAAGTACTTTATGTGTAATGTGTAAATTTTCACCATATTTTTGTACTCTGTAATACTGTCAGCTCTCATGAG
TTTGAATTTGAATTTGGGGCTCTTTTTGATCACTCAGAATCACGTGTTTCCCTCTAGCTGGCCAGTATGAGTAGAGTCC
CTATATTTTGACTTGCACTACAAATACATGTTTTATAATAATTGCTATACATGTGCTTTGTATATTGTTCATCATTATG
ACATAAGCTACCTGACTCCATTTGTGGTTTTTTTTTTTTCTGTTTTGTTTTGTTTTATAAAAAAAGGATGGATTAAAGT
GCTCTCTCCTCCCCTCCTTCCCTTCCTCCTCTCTCATCCCCATTTGTAACACTTGAATCGCAATGCGGTTCAGAGGCAG
AGGGTGACACCCACTCCTGTGCAAAGGGCTGGTACAGAGTATCTGCCTCAGCAATGCCTTTGCATGGGGCATGCATGGG
AGCAGGCTGCCCTGGGCTCGCACACAGCAGGACTTGCCCTGCCGTTAAGCTGTGGGGCTGATCCTGCTCCTAACACAGT
AACAGAGGCTTGCCTTTAACTTCTGCAGTGGCATGGCAGGATTTGCAGGATCAGACTCTTGATTTTTTTTGAGTTTTCA
AACCTATCAAAAGAAAAAAACGGAAAAAGAAATATGGGGTCTCTAGAGCTTTGTTGCTGTTACGCATTTGAATATTGTA
GAGGGAGTTGAAAAATAATCCACATCATACATTTCTTTTCTAAAAAGTTTAAATTGGCAAAAAAAAGTCATGAAGAAGA
CGCAATCATATGATGAATGGTTTTGCATGGCAAAGCTTGAAAACTGCGTTAGAAACACGCAACTTGGATGAGAAGGACA
TTTTCTGTCATTGACCTGAGTGGTGTCAGGAGGATGCTCCCAAGCTTTACGTTGTCAGCTCCAGTTCTAAGATGTGCAA
TTTCTTTGACTTCAGCAGAACACTGATGCAAAGCTGAAGTACCGCAGTGGCTTGCACCCGCCGCTCCTCGGGACTTCAG
CAGAGTCTATGCTTATTGCCTACATGGACACGTAGCCCCACAGATGATCTAATCCCACCCATTGACTCAGCACAGAGGA
GGAGGTACGTTAGACTTCTGATTTATTTAGTGAGTTGAGATGAACAAGTGAAAAATCTGTCCTGCTAACACTTGCTTGA
GCCAGACTTACTCCAGTGAGAAGATGCACTGAACTCAGTGAAACTCCTCAGGGTAGTAAATACTCTGGATTTTGCTGCA
TACAGCAGCAAAATTAGTTTTATCAGGTTCAGTATGAGAACTGTATTTTTGTTGGACAGGAAGGGAGACGTGGATGAAC
ATATTTCAAAAGACTTAAGAACATTTTTGCAATTCTCTGCTAAGGGAATGCAACTCAGAGTGGATTTGAAGCTTTGGAA
AAGTGGAATACAAGATAGCATAGTTGTCCAATTATACTCACTATGCGCTGGACGCAGCTGAAGATTTTGGTTTGGGTTT
GGAGTTTTTGTTGTCTAAATTTAAATAAAAAGCCTTATTTCTGTAAATCATTACTGCAAGATCAGATACTTTTTTTGGT
TTTGTTTTTTTTTTTTTACTTTTTCTCAAAATGCACTGATAGTATTTGAAATATTCTTATAAAGCTCCTACAACTTTTT
TTTTCTCCACTTTATTAGGCATGTATTTCCCTTAATTACCAGTGACGCTATTAGACCTGATCCTACAGTGTGCAGAACT
CATGGGTGAAACACCCCTCTATAGAGTGGTGTGATGTGAGGCCAAACACCACTCAGGTCTGATGTCGATTACCACCCCC
CTCCCCCCCCCAATCAAATGATGTTTAGATGGGACTGCAACAGTTCAAAGACTGACACAATAAGTAGGTAGCTGTTACC
ATCTCAGCAAAGTCCCTGAGCATTGGTGATGCCCAGCACCTGGCAGGAAATGTTCCGCACTTTGAAAGGTCAGACCCAA
AGGAGCTGTGTGAGCCTGAGGGGGGTCTTAGCACTTAGCTGAGTGGGTTAGGACAGCATTTTTTATGTGTTTAGCAACA
ACACAATTGTATGGTTGGCATGGTTTAAAAGAAAAAAAAAAAAAAGGAACTTAAAGGACAGCTGTGTTGTACTTTGGTG
ATCGATTACTCTGTATTTTAACACATTGTATGTCTGTTTTTGTGGTGCTCTAGTGGTAAATAAATTATTTCAATTATA | | Citation | García-Campmany L, Martí E. The TGFbeta intracellular effector Smad3 regulates neuronal differentiation and cell fate specification in the developing spinal cord. Development. 2007 Jan;134(1):65-75. Epub 2006 Nov 30. | | Copyright | Copyright by the authors. Published by the Company of Biologists Ltd. | | Comments | As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI XM_003640970.2 |
MouseFrogFruit FlyZebra FinchZebrafish |
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