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TGFB2 Gene Summary Expression Other Species Expression JBrowse Gene Official Symbol TGFB2 Official Full Name transforming growth factor beta 2 CGNC ID 51471 also known as TGF-beta-2, transforming growth factor beta-2 proprotein|TGF beta2|transforming growth factor-beta2 gene type protein-coding
Genomic Map Sequence Information Gene Expression Orthology Gene Ontology Molecular Function beta-amyloid binding , growth factor activity , protein homodimerization activity , receptor binding , more... receptor signaling protein serine/threonine kinase activity , transforming growth factor beta receptor binding , type II transforming growth factor beta receptor binding Biological Process SMAD protein import into nucleus , activation of protein kinase activity , more... cardiac epithelial to mesenchymal transition , cardiac muscle cell proliferation , cardioblast differentiation , cartilage development , cell cycle arrest , cell death , cell growth , cell migration , cell morphogenesis , cell-cell junction organization , collagen fibril organization , dopamine biosynthetic process , embryo development , embryo development ending in birth or egg hatching , embryonic digestive tract development , endothelial cell activation , epithelial to mesenchymal transition , epithelial to mesenchymal transition involved in endocardial cushion formation , extrinsic apoptotic signaling pathway , eye development , glial cell migration , gonad development , heart development , heart morphogenesis , hemopoiesis , lung development , negative regulation of alkaline phosphatase activity , negative regulation of cell adhesion , negative regulation of cell proliferation , negative regulation of epithelial cell proliferation , negative regulation of macrophage cytokine production , nervous system development , neural tube development , neuron development , neutrophil chemotaxis , organ development , pathway-restricted SMAD protein phosphorylation , positive regulation of cardioblast differentiation , positive regulation of catagen , positive regulation of cell adhesion mediated by integrin , positive regulation of cell cycle , positive regulation of cell division , positive regulation of cell growth , positive regulation of cell proliferation , positive regulation of epithelial cell migration , positive regulation of epithelial to mesenchymal transition , positive regulation of heart contraction , positive regulation of immune response , positive regulation of integrin biosynthetic process , positive regulation of neuron apoptotic process , positive regulation of phosphatidylinositol 3-kinase signaling , positive regulation of protein secretion , positive regulation of stress-activated MAPK cascade , protein phosphorylation , regulation of cell differentiation , regulation of cell proliferation , regulation of growth , regulation of transforming growth factor beta2 production , response to drug , response to hypoxia , response to progesterone , signal transduction by phosphorylation , skeletal muscle tissue development , somatic stem cell division , somitogenesis , spleen development , transforming growth factor beta receptor signaling pathway , wound healing Cellular Component axon , extracellular matrix , extracellular region , extracellular space , neuronal cell body
Links to other databases
Entry 1 GEISHA Id TGFB2.UApcr Data Source GEISHA ISH Analysis Forward cDNA Template Primer CGGCGATGGAGAAAAATGC Reverse cDNA Template Primer AATTAA CCCTCACTAAAGGATGTAGTAGAGGATGGTGAGGGC cDNA Template Length 775 Complete cDNA Template Probe show GTCCACTTGGTGAGGCTGAGTTCAGGGTCTTCCGCCTGCAGAACTCAAAGGCGCGGGTCTCGGAGCAGCGGATAGAGCT
Entry 2 GEISHA Id TGFB2.Yamagishi.2012 Data Source Publication Complete cDNA Template Probe show CTCTCAGCCTGTCTACCTGCAGCACCCTCGACATGGATCAGTTCATGCGCAAGAGGATCGAGGCGATCCGGGGGCAGAT
Citation Yamagishi T, Ando K, Nakamura H, Nakajima Y.
Expression of the Tgfβ2 gene during chick embryogenesis.
Anat Rec (Hoboken). 2012 Feb;295(2):257-67. doi: 10.1002/ar.22400. Epub 2011 Dec 21.
Comments The cDNA template used to generate the probe was obtained by PCR using the information provided in the publication.
Entry 3 GEISHA Id TGFBETA2.GarciaCampmany.2007 Data Source Publication Complete cDNA Template Probe show TCTTTTTTTTTTTTAACTGCCGCTCTCTCCACCCCCGACTCTCACTAGGCTGCTTTTTTATTTTTTTGTATCACTATTG
Citation García-Campmany L, Martí E. The TGFbeta intracellular effector Smad3 regulates neuronal differentiation and cell fate specification in the developing spinal cord. Development. 2007 Jan;134(1):65-75. Epub 2006 Nov 30. Copyright Copyright by the authors. Published by the Company of Biologists Ltd. Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI XM_003640970.2
Entry 4 GEISHA Id Tgfβ2.Lorda-Diez.2014 Data Source Publication Complete cDNA Template Probe show TTTTTTTTCCTTTTTTTTTTTTTTTTTCTTTTGGGTTTTCCACCCTGCGCCGCCAGCTCGCTGCGAACAGACTCTTTTC
Citation Lorda-Diez CI, García-Porrero JA, Hurlé JM, Montero JA. Decorin gene expression in the differentiation of the skeletal connective tissues of the developing limb. Gene Expr Patterns. 2014 May;15(1):52-60. Epub 2014 Apr 24. DOI: 10.1016/j.gep.2014.04.003. Copyright Copyright © 2014 Elsevier B.V. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_001031045).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 25-30 stage 29
stage 30
stage 30
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