GEISHA - A Chicken Embryo Gene Expression Database
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SYK
spleen associated tyrosine kinase

Gene
Official SymbolSYK
Official Full Namespleen associated tyrosine kinase
CGNC ID53036
also known astyrosine-protein kinase SYK|spleen tyrosine kinase
gene typeprotein-coding
Genomic Map
 Ensembl
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
RNANM_001031430
PolypeptideNP_001026601
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST ProfileGga.22529
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly
Human6850ENSG00000165025MIM:600085
Mouse20963ENSMUSG00000021457All phenotypic alleles (9):Targeted, knock-out(3) Targeted, other(6) MGI:99515
Xenopus100486846, 446500978183
Zebrafish405769ENSDARG00000008186ZDB-GENE-040702-3ZFIN:ZDB-GENE-040702-3
Gene Ontology
Molecular FunctionATP binding, integrin binding, non-membrane spanning protein tyrosine kinase activity, more...protein kinase binding, receptor signaling protein tyrosine kinase activity
Biological Processactivation of JUN kinase activity, adaptive immune response, B cell receptor signaling pathway, more...beta selection, blood vessel morphogenesis, cellular response to molecule of fungal origin, defense response to bacterium, enzyme linked receptor protein signaling pathway, innate immune response, integrin-mediated signaling pathway, leukocyte activation involved in immune response, leukocyte cell-cell adhesion, leukotriene biosynthetic process, lymph vessel development, macrophage activation involved in immune response, neutrophil activation involved in immune response, neutrophil chemotaxis, positive regulation of alpha-beta T cell differentiation, positive regulation of alpha-beta T cell proliferation, positive regulation of B cell differentiation, positive regulation of bone resorption, positive regulation of calcium-mediated signaling, positive regulation of cell adhesion mediated by integrin, positive regulation of cytokine secretion, positive regulation of gamma-delta T cell differentiation, positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, positive regulation of interleukin-3 biosynthetic process, positive regulation of mast cell degranulation, positive regulation of peptidyl-tyrosine phosphorylation, protein autophosphorylation, protein phosphorylation, regulation of arachidonic acid secretion, regulation of ERK1 and ERK2 cascade, regulation of neutrophil degranulation, regulation of phagocytosis, regulation of platelet activation, regulation of platelet aggregation, regulation of superoxide anion generation, serotonin secretion by platelet
Cellular ComponentB cell receptor complex, cytosol, early phagosome, T cell receptor complex
Links to other databases
Entrez Gene427272
Ensembl GeneENSGALG00000015216
KEGGgga:427272
No expression data available.
 Data from NCBI Unigene EST Profile
Unigene ID: Gga.22529

Mouse

Emage
EurexpressMGI:99515
MGI GXDMGI:99515

Frog

Xenbase978183

Fruit Fly

BDGP

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-040702-3
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